KIT ligand

Synonym

C-kit ligand, Stem cell factor, KIT ligand, DKFZp686F2250, Kit ligand precursor, SCF, Mast cell growth factor, MGF, KITLG, KL-1, Kitl

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:21.30

cerebellum:50.40

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:17.60

artery/aorta:60

vein:66.60

lymphnode:20.20

peripheral blood:36.40

spleen:37.80

thymus:12.90

bone marrow:-

adipose:-

bone:-

skin:9.60

GeneChip

cerebrum:2.93

cerebellum:2.98

brain stem:2.94

corpus callosum/glia:2.97

pineal gland:-

peripheral nerve:2.76

spine:2.88

retina:-

eye:-

artery/aorta:2.85

vein:3.05

lymphnode:2.84

peripheral blood:-

spleen:2.78

thymus:3.04

bone marrow:3.01

adipose:2.94

bone:-

skin:2.96

CAGE

cerebrum:3.18

cerebellum:-

brain stem:2.31

corpus callosum/glia:2.65

pineal gland:5.09

peripheral nerve:-

spine:2.79

retina:-

eye:-

artery/aorta:3.26

vein:2.95

lymphnode:3.05

peripheral blood:-

spleen:2.00

thymus:1.74

bone marrow:-

adipose:3.42

bone:-

skin:-

RNA-seq

cerebrum:0.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.42

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.70

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:10.90

prostate:-

ovary:-

testis:34.60

heart:51.10

muscle:60.30

esophagus:-

stomach:21.20

intestine:32.40

colon:25.40

liver/hepato:21.10

lung:24.40

bladder:-

kidney:62.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:8.90

breast:9.30

salivary:-

GeneChip

uterus:2.97

placenta:2.79

prostate:2.86

ovary:2.89

testis:2.73

heart:2.87

muscle:3.01

esophagus:2.97

stomach:3.02

intestine:2.98

colon:2.95

liver/hepato:2.88

lung:2.97

bladder:-

kidney:2.84

pituitary:2.79

thyroid/parathyroid:2.81

adrenal gland:2.80

pancreas:3.19

breast:2.82

salivary:2.94

CAGE

uterus:3.73

placenta:2.64

prostate:4.20

ovary:2.86

testis:3.34

heart:3.40

muscle:2.40

esophagus:4.08

stomach:-

intestine:3.55

colon:4.17

liver/hepato:1.71

lung:4.49

bladder:3.75

kidney:4.29

pituitary:1.82

thyroid/parathyroid:2.02

adrenal gland:-

pancreas:1.21

breast:3.75

salivary:2.90

RNA-seq

uterus:-

placenta:-

prostate:1.21

ovary:1.02

testis:2.74

heart:0.39

muscle:0.50

esophagus:-

stomach:-

intestine:-

colon:1.07

liver/hepato:0.25

lung:2.53

bladder:-

kidney:3.38

pituitary:-

thyroid/parathyroid:0.12

adrenal gland:0.77

pancreas:-

breast:1.54

salivary:-

IDs

Refseq ID	NM_003994
Gene ID	4254
Unigene ID	Hs.104806
Probe set ID	207029_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000049130
GTEx ID	ENSG00000049130

Orthologous Gene

Mouse[4]	NM_013598
Rat [0]

Chromosomal Region

12q21.32 [88,885,885 - 88,974,628]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0007155	cell adhesion
GO:0008283	cell proliferation
GO:0035162	embryonic hemopoiesis
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0035234	germ cell programmed cell death
GO:0030097	hemopoiesis
GO:0045087	innate immune response
GO:0008584	male gonad development
GO:0033026	negative regulation of mast cell apoptosis
GO:0048011	nerve growth factor receptor signaling pathway
GO:0001755	neural crest cell migration
GO:0048015	phosphoinositide-mediated signaling
GO:0045740	positive regulation of DNA replication
GO:0043406	positive regulation of MAP kinase activity
GO:0070668	positive regulation of mast cell proliferation
GO:0045636	positive regulation of melanocyte differentiation
GO:0002763	positive regulation of myeloid leukocyte differentiation
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0046579	positive regulation of Ras protein signal transduction
GO:0007165	signal transduction

Cellular Component

GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0016021	integral to membrane
GO:0005886	plasma membrane

Molecular Function

GO:0005125	cytokine activity
GO:0008083	growth factor activity
GO:0005515	protein binding
GO:0005173	stem cell factor receptor binding

KIT ligand

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function