Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1

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Synonym

MSG1, Melanocyte-specific protein 1, CITED1, Cbp/p300-interacting transactivator 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:13 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:52.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:177.60
GeneChip cerebrum:5.89 cerebellum:5.40 brain stem:5.73 corpus callosum/glia:5.17 pineal gland:- peripheral nerve:5.02 spine:5.33 retina:- eye:- artery/aorta:5.21 vein:5.32 lymphnode:4.97 peripheral blood:- spleen:4.67 thymus:4.96 bone marrow:5.14 adipose:5.33 bone:- skin:5.28
CAGE cerebrum:1.75 cerebellum:- brain stem:0.94 corpus callosum/glia:1.01 pineal gland:3.20 peripheral nerve:- spine:0.92 retina:- eye:- artery/aorta:0.34 vein:0.18 lymphnode:0.03 peripheral blood:- spleen:0 thymus:0.18 bone marrow:- adipose:0.55 bone:- skin:-
RNA-seq cerebrum:0.78 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.13 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:10.90 prostate:11.30 ovary:- testis:47.60 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:463.90 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.11 placenta:5.01 prostate:6.06 ovary:5.03 testis:9.34 heart:5.06 muscle:5.50 esophagus:5.18 stomach:4.85 intestine:5.25 colon:5.26 liver/hepato:4.94 lung:5.09 bladder:- kidney:5.09 pituitary:8.65 thyroid/parathyroid:5.69 adrenal gland:5.12 pancreas:5.27 breast:5.74 salivary:4.93
CAGE uterus:1.31 placenta:0.37 prostate:1.58 ovary:0.32 testis:6.04 heart:0.24 muscle:0 esophagus:0.26 stomach:- intestine:0.48 colon:0.44     liver/hepato:0.14    lung:0.35 bladder:0.18 kidney:1.03 pituitary:5.67 thyroid/parathyroid:1.43 adrenal gland:- pancreas:0.58 breast:3.24 salivary:0
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:2.12 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.32 pituitary:- thyroid/parathyroid:1.69 adrenal gland:0.00 pancreas:- breast:0.61 salivary:-

Gene Information

IDs

Refseq ID NM_001144886
Gene ID 4435
Unigene ID Hs.40403
Probe set ID 207144_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000125931
GTEx ID ENSG00000125931

Orthologous Gene

Mouse[1]  NM_007709
Rat [0]  

Chromosomal Region

Xq13.1  [71,521,488  -  71,527,037]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8901575
9434189
9683535
9707553
9721210
10327051
10644012
10722728
11310794
11581164
11744733
12477932
15342556
15489334
15843474
16864582
17336183
17710162
17938205
21172805
21449767
22703800
22889411
23746764
23935526

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0007420  brain development
GO:0001658  branching involved in ureteric bud morphogenesis
GO:0008283  cell proliferation
GO:0000578  embryonic axis specification
GO:0060711  labyrinthine layer development
GO:0042438  melanin biosynthetic process
GO:0030318  melanocyte differentiation
GO:0060231  mesenchymal to epithelial transition
GO:0001656  metanephros development
GO:0003340  negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0043524  negative regulation of neuron apoptosis
GO:0045668  negative regulation of osteoblast differentiation
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0030178  negative regulation of Wnt receptor signaling pathway
GO:0006913  nucleocytoplasmic transport
GO:0043473  pigmentation
GO:0001890  placenta development
GO:0010628  positive regulation of gene expression
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0030511  positive regulation of transforming growth factor beta receptor signaling pathway
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0051591  response to cAMP
GO:0034097  response to cytokine stimulus
GO:0043627  response to estrogen stimulus
GO:0032868  response to insulin stimulus
GO:0034341  response to interferon-gamma
GO:0070555  response to interleukin-1
GO:0071105  response to interleukin-11
GO:0070669  response to interleukin-2
GO:0070670  response to interleukin-4
GO:0070741  response to interleukin-6
GO:0071104  response to interleukin-9
GO:0032496  response to lipopolysaccharide
GO:0071107  response to parathyroid hormone stimulus
GO:0060395  SMAD protein signal transduction
GO:0060712  spongiotrophoblast layer development
GO:0006351  transcription, DNA-dependent
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0001570  vasculogenesis

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005634  nucleus

Molecular Function

GO:0003682  chromatin binding
GO:0070410  co-SMAD binding
GO:0044212  DNA regulatory region binding
GO:0050693  LBD domain binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0042803  protein homodimerization activity
GO:0003713  transcription coactivator activity
GO:0003700  transcription factor activity