ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide

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Synonym

FHM2, ATP1A2, Na+/K+ ATPase 2, MGC59864, KIAA0778, Sodium pump 2, MHP2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:572.40

cerebellum:1259.40

brain stem:-

corpus callosum/glia:87.50

pineal gland:148.30

peripheral nerve:797.50

spine:336.90

retina:-

eye:105.80

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:12.90

bone marrow:78.70

adipose:40.30

bone:-

skin:48

GeneChip

cerebrum:10.66

cerebellum:9.54

brain stem:10.52

corpus callosum/glia:10.19

pineal gland:-

peripheral nerve:9.63

spine:10.90

retina:-

eye:-

artery/aorta:7.75

vein:7.33

lymphnode:5.13

peripheral blood:-

spleen:4.55

thymus:4.37

bone marrow:5.10

adipose:6.67

bone:-

skin:6.35

CAGE

cerebrum:6.32

cerebellum:-

brain stem:6.06

corpus callosum/glia:6.11

pineal gland:4.91

peripheral nerve:-

spine:6.83

retina:-

eye:-

artery/aorta:4.34

vein:4.25

lymphnode:2.05

peripheral blood:-

spleen:0.71

thymus:0.18

bone marrow:-

adipose:4.52

bone:-

skin:-

RNA-seq

cerebrum:7.61

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.96

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.26

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:3.60

prostate:56.30

ovary:-

testis:-

heart:38.30

muscle:361.60

esophagus:-

stomach:-

intestine:32.40

colon:-

liver/hepato:10.60

lung:14.70

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:152.40

pancreas:-

breast:18.60

salivary:-

GeneChip

uterus:5.86

placenta:4.45

prostate:6.56

ovary:5.43

testis:5.45

heart:8.12

muscle:10.17

esophagus:8.19

stomach:6.12

intestine:6.26

colon:6.69

liver/hepato:5.04

lung:5.39

bladder:-

kidney:5.31

pituitary:7.11

thyroid/parathyroid:4.91

adrenal gland:5.21

pancreas:5.99

breast:6.40

salivary:5.37

CAGE

uterus:3.10

placenta:1.08

prostate:3.89

ovary:2.78

testis:2.79

heart:4.71

muscle:6.81

esophagus:4.21

stomach:-

intestine:2.78

colon:3.85

liver/hepato:0.14

lung:2.15

bladder:4.04

kidney:1.63

pituitary:3.30

thyroid/parathyroid:2.85

adrenal gland:-

pancreas:0

breast:3.09

salivary:2.12

RNA-seq

uterus:-

placenta:-

prostate:4.61

ovary:2.32

testis:4.17

heart:5.73

muscle:8.30

esophagus:-

stomach:-

intestine:-

colon:4.87

liver/hepato:0.17

lung:1.83

bladder:-

kidney:1.53

pituitary:-

thyroid/parathyroid:5.07

adrenal gland:2.87

pancreas:-

breast:3.84

salivary:-

IDs

Refseq ID	NM_000702
Gene ID	477
Unigene ID	Hs.34114
Probe set ID	203295_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000018625
GTEx ID	ENSG00000018625

Orthologous Gene

Mouse[4]	NM_178405
Rat [0]

Chromosomal Region

1q23.2 [160,085,549 - 160,113,381]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

LRG_6 [5,001 - 32,834]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR006069	ATPase, P-type cation exchange, alpha subunit
IPR005775	ATPase, P-type cation exchange, alpha subunit, eukaryotic
IPR001757	ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter

Gene Ontology (GO ID)

Biological Process

GO:0008344	adult locomotory behavior
GO:0006754	ATP biosynthetic process
GO:0015991	ATP hydrolysis coupled proton transport
GO:0071260	cellular response to mechanical stimulus
GO:0034220	ion transmembrane transport
GO:0040011	locomotion
GO:0045822	negative regulation of heart contraction
GO:0045988	negative regulation of striated muscle contraction
GO:0001504	neurotransmitter uptake
GO:0006813	potassium ion transport
GO:0051481	reduction of cytosolic calcium ion concentration
GO:0008217	regulation of blood pressure
GO:0002087	regulation of respiratory gaseous exchange by neurological system process
GO:0006940	regulation of smooth muscle contraction
GO:0006942	regulation of striated muscle contraction
GO:0002026	regulation of the force of heart contraction
GO:0019229	regulation of vasoconstriction
GO:0035094	response to nicotine
GO:0006814	sodium ion transport
GO:0055085	transmembrane transport
GO:0008542	visual learning

Cellular Component

GO:0005901	caveola
GO:0005737	cytoplasm
GO:0043197	dendritic spine
GO:0005768	endosome
GO:0005886	plasma membrane
GO:0005890	sodium:potassium-exchanging ATPase complex
GO:0045202	synapse
GO:0030315	T-tubule

Molecular Function

GO:0005524	ATP binding
GO:0046872	metal ion binding
GO:0005391	sodium:potassium-exchanging ATPase activity

ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function