nodal homolog (mouse)

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Synonym

NODAL, MGC138230, mouse, nodal homolog (mouse), Nodal homolog precursor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:8.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:4.80
GeneChip nodata
CAGE cerebrum:0.18 cerebellum:- brain stem:0.17 corpus callosum/glia:0.52 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0.18 lymphnode:0 peripheral blood:- spleen:0 thymus:0.06 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.39 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.02 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.62 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:3.60 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:0 placenta:0 prostate:0.08 ovary:0 testis:0 heart:0 muscle:0.05 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.33 ovary:0.23 testis:0.47 heart:0.06 muscle:0.67 esophagus:- stomach:- intestine:- colon:0.04     liver/hepato:0.01        lung:0.24    bladder:- kidney:0.08 pituitary:- thyroid/parathyroid:0.35 adrenal gland:0.37 pancreas:- breast:0.41 salivary:-

Gene Information

IDs

Refseq ID NM_018055
Gene ID 4838
Unigene ID Hs.370414
Probe set ID -
Ensembl ID ENSG00000156574
GTEx ID ENSG00000156574

Orthologous Gene

Mouse[2]  NM_013611
Rat [0]  

Chromosomal Region

10q22.1  [72,192,071  -  72,207,707]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8429908
9354794
12052855
12477932
12606401
15150278
15257293
15308665
15475956
15489334
15501227
15982639
16179608
16385451
17373879
17925387
18022151
18089557
18234825
18538293
18596037
19064609
19279133
19386982
19553149
19874624
19913121
20301702
20383200
20482672
20495543
20628086
20629020
20734064
20819778
21116837
21159651
21356369
21532621
21630377
21656830
21741376
22002671
22031289
22352765
22381624
22454525
22469982
22508696
22577960
22855743
23034635
23144858
23201575
23334323
23424236
23474366
23591895
23911596
24114072
24120944
24186978
24370825
24459810

Gene Ontology  (GO ID)

Biological Process

GO:0048327  axial mesodermal cell fate specification
GO:0007420  brain development
GO:0042074  cell migration involved in gastrulation
GO:0048546  digestive tract morphogenesis
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0009880  embryonic pattern specification
GO:0001892  embryonic placenta development
GO:0060136  embryonic process involved in female pregnancy
GO:0060802  epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification
GO:0033505  floor plate morphogenesis
GO:0048859  formation of anatomical boundary
GO:0040007  growth
GO:0001947  heart looping
GO:0002085  inhibition of neuroepithelial cell differentiation
GO:0060460  left lung morphogenesis
GO:0001889  liver development
GO:0048382  mesendoderm development
GO:0060766  negative regulation of androgen receptor signaling pathway
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0001842  neural fold formation
GO:0001890  placenta development
GO:0010085  polarity specification of proximal/distal axis
GO:0032927  positive regulation of activin receptor signaling pathway
GO:0045766  positive regulation of angiogenesis
GO:0043280  positive regulation of caspase activity
GO:0022409  positive regulation of cell-cell adhesion
GO:0050679  positive regulation of epithelial cell proliferation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0010862  positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0060391  positive regulation of SMAD protein nuclear translocation
GO:0051091  positive regulation of transcription factor activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0010575  positive regulation vascular endothelial growth factor production
GO:0010470  regulation of gastrulation
GO:0060395  SMAD protein signal transduction
GO:0019827  stem cell maintenance
GO:0090010  transforming growth factor beta receptor signaling pathway involved in primitive streak formation
GO:0001831  trophectodermal cellular morphogenesis
GO:0001944  vasculature development

Cellular Component

GO:0005615  extracellular space

Molecular Function

GO:0005125  cytokine activity
GO:0008083  growth factor activity
GO:0016015  morphogen activity
GO:0048018  receptor agonist activity
GO:0070698  type I activin receptor binding