Notch homolog 2 (Drosophila)

Synonym

hN2, Neurogenic locus notch homolog protein 2 precursor, Notch 2, Notch (Drosophila) homolog 2, NOTCH2, Notch homolog 2 (Drosophila)

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:71.10

cerebellum:50.40

brain stem:-

corpus callosum/glia:29.20

pineal gland:296.70

peripheral nerve:214.70

spine:-

retina:237.30

eye:88.20

artery/aorta:30

vein:-

lymphnode:70.80

peripheral blood:200.40

spleen:56.70

thymus:64.40

bone marrow:551.10

adipose:121

bone:127.90

skin:120

GeneChip

cerebrum:6.71

cerebellum:6.33

brain stem:6.58

corpus callosum/glia:6.79

pineal gland:-

peripheral nerve:7.28

spine:7.13

retina:-

eye:-

artery/aorta:7.26

vein:6.94

lymphnode:6.69

peripheral blood:-

spleen:7.34

thymus:6.76

bone marrow:6.98

adipose:7.66

bone:-

skin:7.39

CAGE

cerebrum:0.43

cerebellum:-

brain stem:0.44

corpus callosum/glia:0.39

pineal gland:0.35

peripheral nerve:-

spine:0.66

retina:-

eye:-

artery/aorta:1.82

vein:0.96

lymphnode:0.69

peripheral blood:-

spleen:0.92

thymus:0.71

bone marrow:-

adipose:0.84

bone:-

skin:-

RNA-seq

cerebrum:3.12

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.71

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:127.60

placenta:145.70

prostate:78.90

ovary:37.30

testis:129.80

heart:140.50

muscle:20.10

esophagus:-

stomach:85

intestine:32.40

colon:76.30

liver/hepato:63.30

lung:161.30

bladder:-

kidney:114.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:62.20

breast:362.40

salivary:-

GeneChip

uterus:7.57

placenta:7.72

prostate:7.55

ovary:7.93

testis:7.40

heart:7.04

muscle:6.42

esophagus:7.38

stomach:6.87

intestine:6.88

colon:7.23

liver/hepato:6.80

lung:6.99

bladder:-

kidney:6.63

pituitary:6.63

thyroid/parathyroid:7.01

adrenal gland:6.88

pancreas:7.17

breast:7.32

salivary:6.82

CAGE

uterus:1.02

placenta:0.88

prostate:1.00

ovary:1.06

testis:2.06

heart:1.02

muscle:0.62

esophagus:1.08

stomach:-

intestine:0.21

colon:1.12

liver/hepato:0.84

lung:1.06

bladder:0.95

kidney:0.62

pituitary:0.50

thyroid/parathyroid:0.98

adrenal gland:-

pancreas:1.42

breast:0

salivary:1.58

RNA-seq

uterus:-

placenta:-

prostate:3.88

ovary:4.60

testis:4.41

heart:2.11

muscle:2.11

esophagus:-

stomach:-

intestine:-

colon:3.56

liver/hepato:3.18

lung:3.85

bladder:-

kidney:3.02

pituitary:-

thyroid/parathyroid:4.05

adrenal gland:3.47

pancreas:-

breast:4.69

salivary:-

IDs

Refseq ID	NM_024408
Gene ID	4853
Unigene ID	Hs.487360
Probe set ID	210756_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000134250
GTEx ID	ENSG00000134250

Orthologous Gene

Mouse[2]	NM_010928
Rat [0]

Chromosomal Region

1p11.2 [120,454,176 - 120,612,240]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001881	EGF-like calcium-binding
IPR000742	EGF-like, type 3

Gene Ontology (GO ID)

Biological Process

GO:0060413	atrial septum morphogenesis
GO:0046849	bone remodeling
GO:0007050	cell cycle arrest
GO:0001709	cell fate determination
GO:0016049	cell growth
GO:0007368	determination of left/right symmetry
GO:0030326	embryonic limb morphogenesis
GO:0010467	gene expression
GO:0030097	hemopoiesis
GO:0006959	humoral immune response
GO:0001701	in utero embryonic development
GO:0006917	induction of apoptosis
GO:0002437	inflammatory response to antigenic stimulus
GO:0002011	morphogenesis of an epithelial sheet
GO:0007275	multicellular organismal development
GO:0043066	negative regulation of apoptosis
GO:0008285	negative regulation of cell proliferation
GO:0007399	nervous system development
GO:0007220	Notch receptor processing
GO:0007219	Notch signaling pathway
GO:0009887	organ morphogenesis
GO:0060674	placenta blood vessel development
GO:0046579	positive regulation of Ras protein signal transduction
GO:0003184	pulmonary valve morphogenesis
GO:0006355	regulation of transcription, DNA-dependent
GO:0019827	stem cell maintenance
GO:0006367	transcription initiation from RNA polymerase II promoter

Cellular Component

GO:0009986	cell surface
GO:0005789	endoplasmic reticulum membrane
GO:0005576	extracellular region
GO:0000139	Golgi membrane
GO:0005887	integral to plasma membrane
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0004872	receptor activity

Notch homolog 2 (Drosophila)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function