nuclear receptor subfamily 4, group A, member 2

Synonym

Orphan nuclear receptor NR4A2, TINUR, nuclear receptor subfamily 4, group A, member 2, NOT, Immediate-early response protein NOT, NR4A2, NURR1, Orphan nuclear receptor NURR1, HZF-3, Transcriptionally-inducible nuclear receptor

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:162.40

cerebellum:277.10

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:92

spine:336.90

retina:-

eye:58.80

artery/aorta:-

vein:-

lymphnode:30.30

peripheral blood:145.70

spleen:18.90

thymus:25.80

bone marrow:39.40

adipose:-

bone:12.80

skin:33.60

GeneChip

cerebrum:4.97

cerebellum:7.29

brain stem:5.71

corpus callosum/glia:4.80

pineal gland:-

peripheral nerve:7.81

spine:6.24

retina:-

eye:-

artery/aorta:7.29

vein:6.83

lymphnode:5.38

peripheral blood:-

spleen:5.62

thymus:5.10

bone marrow:5.38

adipose:6.21

bone:-

skin:6.11

CAGE

cerebrum:3.20

cerebellum:-

brain stem:3.00

corpus callosum/glia:3.54

pineal gland:3.63

peripheral nerve:-

spine:3.52

retina:-

eye:-

artery/aorta:4.58

vein:3.42

lymphnode:2.59

peripheral blood:-

spleen:2.38

thymus:2.27

bone marrow:-

adipose:3.48

bone:-

skin:-

RNA-seq

cerebrum:1.86

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.30

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.40

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:36.50

placenta:-

prostate:22.50

ovary:-

testis:34.60

heart:12.80

muscle:20.10

esophagus:-

stomach:42.50

intestine:-

colon:8.50

liver/hepato:63.30

lung:161.30

bladder:125.60

kidney:10.40

pituitary:232

thyroid/parathyroid:-

adrenal gland:253.90

pancreas:8.90

breast:9.30

salivary:-

GeneChip

uterus:5.75

placenta:4.43

prostate:8

ovary:7.49

testis:4.14

heart:6.54

muscle:4.45

esophagus:5.25

stomach:6.24

intestine:5.40

colon:5

liver/hepato:5.41

lung:7.47

bladder:-

kidney:5.99

pituitary:7.62

thyroid/parathyroid:6.34

adrenal gland:8.61

pancreas:5

breast:5.68

salivary:7.67

CAGE

uterus:3.20

placenta:1.99

prostate:4.04

ovary:5.58

testis:3.17

heart:3.31

muscle:3.21

esophagus:3.32

stomach:-

intestine:3.32

colon:2.86

liver/hepato:3.06

lung:4.13

bladder:4.26

kidney:1.89

pituitary:3.79

thyroid/parathyroid:2.73

adrenal gland:-

pancreas:2.48

breast:3.71

salivary:4.60

RNA-seq

uterus:-

placenta:-

prostate:4.64

ovary:5.89

testis:2.15

heart:1.96

muscle:1.78

esophagus:-

stomach:-

intestine:-

colon:1.63

liver/hepato:0.33

lung:4.20

bladder:-

kidney:1.05

pituitary:-

thyroid/parathyroid:1.36

adrenal gland:0.93

pancreas:-

breast:3.07

salivary:-

IDs

Refseq ID	NM_006186
Gene ID	4929
Unigene ID	Hs.563344
Probe set ID	204622_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000153234
GTEx ID	ENSG00000153234

Orthologous Gene

Mouse[4]	NM_001139509, NM_013613
Rat [0]

Chromosomal Region

2q24.1 [157,180,944 - 157,198,860]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR003070	Orphan nuclear receptor
IPR003073	Orphan nuclear receptor, NURR type
IPR003078	Retinoic acid receptor
IPR001723	Steroid hormone receptor
IPR013088	Zinc finger, NHR/GATA-type
IPR001628	Zinc finger, nuclear hormone receptor-type

Gene Ontology (GO ID)

Biological Process

GO:0008344	adult locomotory behavior
GO:0031668	cellular response to extracellular stimulus
GO:0033554	cellular response to stress
GO:0021952	central nervous system projection neuron axonogenesis
GO:0016265	death
GO:0042416	dopamine biosynthetic process
GO:0010467	gene expression
GO:0021986	habenula development
GO:0030522	intracellular receptor-mediated signaling pathway
GO:0043524	negative regulation of neuron apoptosis
GO:0042551	neuron maturation
GO:0001764	neuron migration
GO:0043085	positive regulation of catalytic activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0009791	post-embryonic development
GO:0042053	regulation of dopamine metabolic process
GO:0043576	regulation of respiratory gaseous exchange
GO:0001975	response to amphetamine
GO:0001666	response to hypoxia
GO:0010035	response to inorganic substance
GO:0017085	response to insecticide
GO:0007165	signal transduction
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005737	cytoplasm
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0004879	ligand-dependent nuclear receptor activity
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0043565	sequence-specific DNA binding
GO:0003707	steroid hormone receptor activity
GO:0008270	zinc ion binding

nuclear receptor subfamily 4, group A, member 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function