optic atrophy 1 (autosomal dominant)

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Synonym

optic atrophy 1 (autosomal dominant), Optic atrophy protein 1, largeG, NTG, FLJ12460, KIAA0567, NPG, OPA1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:7.10

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:5.90

artery/aorta:-

vein:-

lymphnode:10.10

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:4.80

GeneChip

cerebrum:7.82

cerebellum:7.16

brain stem:7.88

corpus callosum/glia:7.05

pineal gland:-

peripheral nerve:7.96

spine:7.58

retina:-

eye:-

artery/aorta:6.62

vein:6.99

lymphnode:6.54

peripheral blood:-

spleen:6.54

thymus:6.93

bone marrow:7.10

adipose:6.94

bone:-

skin:6.68

CAGE

cerebrum:4.65

cerebellum:-

brain stem:4.48

corpus callosum/glia:3.97

pineal gland:4.39

peripheral nerve:-

spine:4.51

retina:-

eye:-

artery/aorta:3.75

vein:3.87

lymphnode:4.07

peripheral blood:-

spleen:4.07

thymus:4.21

bone marrow:-

adipose:4.23

bone:-

skin:-

RNA-seq

cerebrum:0.36

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.19

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:10.90

prostate:22.50

ovary:-

testis:-

heart:25.50

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:14.70

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:163.70

adrenal gland:-

pancreas:26.70

breast:27.90

salivary:-

GeneChip

uterus:6.90

placenta:7.04

prostate:6.92

ovary:6.64

testis:6.26

heart:7.59

muscle:7.65

esophagus:6.57

stomach:6.59

intestine:6.85

colon:6.29

liver/hepato:6.66

lung:6.06

bladder:-

kidney:6.43

pituitary:6.89

thyroid/parathyroid:6.75

adrenal gland:6.56

pancreas:6.38

breast:6.78

salivary:6.12

CAGE

uterus:4.11

placenta:3.82

prostate:3.94

ovary:3.96

testis:3.72

heart:4.63

muscle:4.92

esophagus:4.21

stomach:-

intestine:4.32

colon:4.16

liver/hepato:4.23

lung:3.87

bladder:4.20

kidney:4.09

pituitary:4.29

thyroid/parathyroid:3.64

adrenal gland:-

pancreas:3.67

breast:4.07

salivary:3.90

RNA-seq

uterus:-

placenta:-

prostate:0.02

ovary:0.55

testis:0.00

heart:1.02

muscle:1.60

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.45

lung:0.49

bladder:-

kidney:0.00

pituitary:-

thyroid/parathyroid:0.95

adrenal gland:0.33

pancreas:-

breast:0.95

salivary:-

IDs

Refseq ID	NM_130837
Gene ID	4976
Unigene ID	Hs.594504
Probe set ID	212213_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000198836
GTEx ID	ENSG00000198836

Orthologous Gene

Mouse[2]	NM_001199177, NM_133752
Rat [0]

Chromosomal Region

3q29 [193,310,933 - 193,415,612]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0019896	axon transport of mitochondrion
GO:0006184	GTP catabolic process
GO:0007007	inner mitochondrial membrane organization
GO:0000266	mitochondrial fission
GO:0008053	mitochondrial fusion
GO:0007005	mitochondrion organization
GO:0090201	negative regulation of release of cytochrome c from mitochondria
GO:0001843	neural tube closure
GO:0007601	visual perception

Cellular Component

GO:0030425	dendrite
GO:0016021	integral to membrane
GO:0030061	mitochondrial crista
GO:0005743	mitochondrial inner membrane
GO:0005758	mitochondrial intermembrane space
GO:0005741	mitochondrial outer membrane
GO:0005739	mitochondrion

Molecular Function

GO:0005525	GTP binding
GO:0003924	GTPase activity
GO:0000287	magnesium ion binding
GO:0005515	protein binding

optic atrophy 1 (autosomal dominant)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function