purinergic receptor P2Y, G-protein coupled, 1

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Synonym

P2Y1, P2RY1, P2Y purinoceptor 1, purinergic receptor P2Y, G-protein coupled, 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:3.73 cerebellum:3.42 brain stem:3.54 corpus callosum/glia:3.75 pineal gland:- peripheral nerve:3.94 spine:3.91 retina:- eye:- artery/aorta:3.32 vein:3.36 lymphnode:3.45 peripheral blood:- spleen:3.24 thymus:3.16 bone marrow:3.58 adipose:3.44 bone:- skin:3.63
CAGE cerebrum:2.47 cerebellum:- brain stem:1.65 corpus callosum/glia:2.41 pineal gland:1.51 peripheral nerve:- spine:2.35 retina:- eye:- artery/aorta:1.03 vein:1.10 lymphnode:1.95 peripheral blood:- spleen:1.83 thymus:1.90 bone marrow:- adipose:2.05 bone:- skin:-
RNA-seq cerebrum:0.71 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.37 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.49 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:3.76 placenta:4.36 prostate:4.35 ovary:3.61 testis:3.21 heart:3.54 muscle:3.65 esophagus:4.68 stomach:3.40 intestine:3.60 colon:3.88 liver/hepato:3.39 lung:3.85 bladder:- kidney:3.34 pituitary:3.32 thyroid/parathyroid:3.26 adrenal gland:3.30 pancreas:3.97 breast:3.43 salivary:3.45
CAGE uterus:2.82 placenta:3.12 prostate:2.41 ovary:2.28 testis:1.60 heart:1.68 muscle:1.23 esophagus:2.99 stomach:- intestine:2.41 colon:2.79     liver/hepato:1.51    lung:3.22 bladder:1.78 kidney:0.82 pituitary:0.83 thyroid/parathyroid:0.64 adrenal gland:- pancreas:0.94 breast:1.68 salivary:0
RNA-seq uterus:- placenta:- prostate:0.99 ovary:1.60 testis:0.59 heart:1.14 muscle:0.11 esophagus:- stomach:- intestine:- colon:1.52     liver/hepato:0.40        lung:1.26    bladder:- kidney:0.31 pituitary:- thyroid/parathyroid:0.51 adrenal gland:0.46 pancreas:- breast:0.31 salivary:-

Gene Information

IDs

Refseq ID NM_002563
Gene ID 5028
Unigene ID -
Probe set ID 207455_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000169860
GTEx ID ENSG00000169860

Orthologous Gene

Mouse[1]  NM_008772
Rat [0]  

Chromosomal Region

3q25.2  [152,552,736  -  152,555,841]

Gene Family (Interpro ID)

IPR000276  7TM GPCR, rhodopsin-like
IPR017452  GPCR, rhodopsin-like superfamily
IPR002286  P2 purinoceptor
IPR000142  P2Y purinoceptor

Link to Pubmed  (Pubmed ID)

8579591
8630005
8666290
9038354
9039850
9268704
9442040
9671706
11159687
11390975
11578839
11690642
11904146
12147294
12393588
12477932
12603858
12623443
12787128
12871508
12880424
14644082
14742685
15099288
15187029
15203713
15284110
15489334
15496502
15509659
15514209
15590415
15602005
15665114
16267125
16546137
16581111
16634769
16741950
16804093
16848759
17095747
17559347
17824841
18057028
18174464
18240029
18270199
18310463
18500760
18502966
18577758
18799799
19132198
19637098
19740098
19913121
19934793
20056178
20063989
20070609
20192270
20473398
20586915
20628086
20847060
21210088
21632028
21643756
22052557
22079667
22249129
22250198
22450808
22574824
22610502
22701645
22721490
22916275
23326583
23951072
24071464
24524250

Gene Ontology  (GO ID)

Biological Process

GO:0007200  activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0007568  aging
GO:0007596  blood coagulation
GO:0007420  brain development
GO:0007166  cell surface receptor linked signal transduction
GO:0042755  eating behavior
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007193  inhibition of adenylate cyclase activity by G-protein signaling pathway
GO:0051100  negative regulation of binding
GO:0010700  negative regulation of norepinephrine secretion
GO:0030168  platelet activation
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0046887  positive regulation of hormone secretion
GO:0032962  positive regulation of inositol trisphosphate biosynthetic process
GO:0043270  positive regulation of ion transport
GO:0060406  positive regulation of penile erection
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0010469  regulation of receptor activity
GO:0042312  regulation of vasodilation
GO:0090075  relaxation of muscle
GO:0070848  response to growth factor stimulus
GO:0009612  response to mechanical stimulus
GO:0019233  sensory perception of pain

Cellular Component

GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0030425  dendrite
GO:0005887  integral to plasma membrane
GO:0005886  plasma membrane
GO:0045211  postsynaptic membrane

Molecular Function

GO:0031686  A1 adenosine receptor binding
GO:0043531  ADP binding
GO:0045032  ADP-activated nucleotide receptor activity
GO:0005524  ATP binding
GO:0045031  ATP-activated nucleotide receptor activity
GO:0046982  protein heterodimerization activity
GO:0045028  purinergic nucleotide receptor activity, G-protein coupled
GO:0004872  receptor activity