pregnancy-associated plasma protein A, pappalysin 1

Synonym

PAPPA, DIPLA1, PAPPA1, Pregnancy-associated plasma protein-A, Pappalysin-1 precursor, PAPA, PAPP-A, IGFBP-4ase, ASBABP2, IGF-dependent IGFBP-4 protease

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:79.40

cerebellum:88.20

brain stem:-

corpus callosum/glia:87.50

pineal gland:296.70

peripheral nerve:-

spine:224.60

retina:118.60

eye:111.70

artery/aorta:30

vein:-

lymphnode:-

peripheral blood:18.20

spleen:56.70

thymus:12.90

bone marrow:-

adipose:80.70

bone:25.60

skin:38.40

GeneChip

cerebrum:5.28

cerebellum:5.35

brain stem:5.34

corpus callosum/glia:5.24

pineal gland:-

peripheral nerve:5.24

spine:5.16

retina:-

eye:-

artery/aorta:5.30

vein:5.42

lymphnode:5.15

peripheral blood:-

spleen:5.09

thymus:4.93

bone marrow:5.48

adipose:5.32

bone:-

skin:5.40

CAGE

cerebrum:0.17

cerebellum:-

brain stem:0.52

corpus callosum/glia:0.66

pineal gland:0.71

peripheral nerve:-

spine:1.03

retina:-

eye:-

artery/aorta:2.38

vein:0.79

lymphnode:1.30

peripheral blood:-

spleen:0.61

thymus:0.12

bone marrow:-

adipose:1.16

bone:-

skin:-

RNA-seq

cerebrum:0.10

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.87

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.60

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:82

placenta:244.10

prostate:180.20

ovary:-

testis:129.80

heart:12.80

muscle:-

esophagus:-

stomach:42.50

intestine:-

colon:59.40

liver/hepato:21.10

lung:19.60

bladder:-

kidney:104

pituitary:-

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:8.90

breast:46.50

salivary:-

GeneChip

uterus:5.25

placenta:11.18

prostate:4.95

ovary:5.20

testis:5.14

heart:5.39

muscle:5.48

esophagus:5.16

stomach:5.18

intestine:5.24

colon:5.36

liver/hepato:5.14

lung:5.27

bladder:-

kidney:5.38

pituitary:5.16

thyroid/parathyroid:5.07

adrenal gland:5.11

pancreas:5.79

breast:5

salivary:5.48

CAGE

uterus:2.23

placenta:8.00

prostate:1.63

ovary:1.71

testis:1.24

heart:1.84

muscle:0.24

esophagus:1.89

stomach:-

intestine:0.43

colon:1.63

liver/hepato:0.26

lung:0.88

bladder:2.21

kidney:2.93

pituitary:0.99

thyroid/parathyroid:0.88

adrenal gland:-

pancreas:1.21

breast:1.16

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:1.36

ovary:0.71

testis:0.84

heart:0.52

muscle:0.10

esophagus:-

stomach:-

intestine:-

colon:1.33

liver/hepato:0.13

lung:0.81

bladder:-

kidney:1.94

pituitary:-

thyroid/parathyroid:0.67

adrenal gland:0.71

pancreas:-

breast:0.16

salivary:-

IDs

Refseq ID	NM_002581
Gene ID	5069
Unigene ID	Hs.643599
Probe set ID	201982_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000182752
GTEx ID	ENSG00000182752

Orthologous Gene

Mouse[1]	NM_021362
Rat[1]	NM_001107939

Chromosomal Region

9q33.1 [118,916,083 - 119,164,601]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000436

Sushi/SCR/CCP

Gene Ontology (GO ID)

Biological Process

GO:0030154	cell differentiation
GO:0044267	cellular protein metabolic process
GO:0007565	female pregnancy
GO:0006508	proteolysis
GO:0032354	response to follicle-stimulating hormone stimulus
GO:0051384	response to glucocorticoid stimulus

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0016020	membrane

Molecular Function

GO:0004175	endopeptidase activity
GO:0008237	metallopeptidase activity
GO:0008270	zinc ion binding

pregnancy-associated plasma protein A, pappalysin 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function