paired box 2

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Synonym

PAX2, paired box gene 2, Paired box protein Pax-2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:2.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:29.40

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:3.72

cerebellum:4.17

brain stem:3.93

corpus callosum/glia:3.59

pineal gland:-

peripheral nerve:3.51

spine:4.14

retina:-

eye:-

artery/aorta:3.70

vein:3.90

lymphnode:3.53

peripheral blood:-

spleen:3.52

thymus:3.57

bone marrow:3.52

adipose:3.63

bone:-

skin:3.86

CAGE

cerebrum:0.20

cerebellum:-

brain stem:0.09

corpus callosum/glia:0

pineal gland:0

peripheral nerve:-

spine:1.45

retina:-

eye:-

artery/aorta:0

vein:0

lymphnode:0

peripheral blood:-

spleen:0

thymus:0.06

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:8.70

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:4.90

bladder:-

kidney:145.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:4.28

placenta:3.51

prostate:3.72

ovary:4.39

testis:3.69

heart:3.61

muscle:4.02

esophagus:3.56

stomach:3.55

intestine:3.64

colon:3.70

liver/hepato:3.63

lung:3.61

bladder:-

kidney:7.85

pituitary:3.82

thyroid/parathyroid:3.55

adrenal gland:3.60

pancreas:4.02

breast:3.69

salivary:3.60

CAGE

uterus:1.51

placenta:0.30

prostate:1.16

ovary:1.59

testis:1.49

heart:0.03

muscle:0

esophagus:0.09

stomach:-

intestine:0

colon:0

liver/hepato:0

lung:0

bladder:0.83

kidney:3.89

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.05

ovary:0.04

testis:0.06

heart:0

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0

liver/hepato:0

lung:0

bladder:-

kidney:0.86

pituitary:-

thyroid/parathyroid:0.00

adrenal gland:0.00

pancreas:-

breast:0

salivary:-

IDs

Refseq ID	NM_003988
Gene ID	5076
Unigene ID	Hs.155644
Probe set ID	206228_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000075891
GTEx ID	ENSG00000075891

Orthologous Gene

Mouse[1]	NM_011037
Rat[1]	NM_001106361

Chromosomal Region

10q24.31 [102,495,360 - 102,589,698]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001523	Paired box protein, N-terminal
IPR011991	Winged helix repressor DNA-binding

Gene Ontology (GO ID)

Biological Process

GO:0007568	aging
GO:0007409	axonogenesis
GO:0048854	brain morphogenesis
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0043010	camera-type eye development
GO:0001709	cell fate determination
GO:0071364	cellular response to epidermal growth factor stimulus
GO:0071333	cellular response to glucose stimulus
GO:0070301	cellular response to hydrogen peroxide
GO:0071260	cellular response to mechanical stimulus
GO:0071300	cellular response to retinoic acid
GO:0090102	cochlea development
GO:0090103	cochlea morphogenesis
GO:0010001	glial cell differentiation
GO:0042472	inner ear morphogenesis
GO:0060231	mesenchymal to epithelial transition
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0007501	mesodermal cell fate specification
GO:0001823	mesonephros development
GO:0043066	negative regulation of apoptosis
GO:0043154	negative regulation of caspase activity
GO:0045918	negative regulation of cytolysis
GO:0043069	negative regulation of programmed cell death
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0001843	neural tube closure
GO:0002072	optic cup morphogenesis involved in camera-type eye development
GO:0021554	optic nerve development
GO:0021631	optic nerve morphogenesis
GO:0021633	optic nerve structural organization
GO:0031016	pancreas development
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
GO:0050679	positive regulation of epithelial cell proliferation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0048793	pronephros development
GO:0043491	protein kinase B signaling cascade
GO:0031667	response to nutrient levels
GO:0003406	retinal pigment epithelium development
GO:0048863	stem cell differentiation
GO:0006366	transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-dependent
GO:0001655	urogenital system development
GO:0021650	vestibulocochlear nerve formation
GO:0007601	visual perception

Cellular Component

GO:0034451	centriolar satellite
GO:0005764	lysosome
GO:0005815	microtubule organizing center
GO:0005634	nucleus
GO:0043234	protein complex
GO:0032993	protein-DNA complex

Molecular Function

GO:0070742	C2H2 zinc finger domain binding
GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0005515	protein binding
GO:0016175	superoxide-generating NADPH oxidase activity

paired box 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function