toll-like receptor 7

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Synonym

UNQ248/PRO285, Toll-like receptor 7 precursor, TLR7, toll-like receptor 7

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:3.44

cerebellum:3.08

brain stem:3.54

corpus callosum/glia:3.92

pineal gland:-

peripheral nerve:3.69

spine:4.19

retina:-

eye:-

artery/aorta:3.34

vein:3.21

lymphnode:3.97

peripheral blood:-

spleen:3.95

thymus:3.70

bone marrow:3.20

adipose:3.34

bone:-

skin:3.14

CAGE

cerebrum:2.49

cerebellum:-

brain stem:3.42

corpus callosum/glia:3.36

pineal gland:1.70

peripheral nerve:-

spine:4.00

retina:-

eye:-

artery/aorta:1.75

vein:2.60

lymphnode:2.55

peripheral blood:-

spleen:2.88

thymus:2.88

bone marrow:-

adipose:1.86

bone:-

skin:-

RNA-seq

cerebrum:1.22

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.41

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.14

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:3.26

placenta:3.49

prostate:3.23

ovary:3.26

testis:2.95

heart:3.09

muscle:3.20

esophagus:3.07

stomach:3.21

intestine:3.13

colon:3.07

liver/hepato:3.21

lung:3.68

bladder:-

kidney:3.09

pituitary:3.26

thyroid/parathyroid:3.20

adrenal gland:3.48

pancreas:3.01

breast:3.58

salivary:3.34

CAGE

uterus:1.52

placenta:2.87

prostate:2.10

ovary:1.65

testis:0.83

heart:0.96

muscle:0.63

esophagus:1.26

stomach:-

intestine:1.97

colon:0.88

liver/hepato:0.78

lung:2.55

bladder:1.24

kidney:1.37

pituitary:1.27

thyroid/parathyroid:0.79

adrenal gland:-

pancreas:0.94

breast:1.68

salivary:2.26

RNA-seq

uterus:-

placenta:-

prostate:0.72

ovary:0.68

testis:0.40

heart:0.37

muscle:0.04

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.05

lung:0.25

bladder:-

kidney:0.17

pituitary:-

thyroid/parathyroid:0.13

adrenal gland:1.41

pancreas:-

breast:0.56

salivary:-

IDs

Refseq ID	NM_016562
Gene ID	51284
Unigene ID	-
Probe set ID	220146_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000196664
GTEx ID	ENSG00000196664

Orthologous Gene

Mouse[1]	NM_133211
Rat[1]	NM_001097582

Chromosomal Region

Xp22.2 [12,885,202 - 12,908,499]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000157

Toll-Interleukin receptor

Gene Ontology (GO ID)

Biological Process

GO:0071260	cellular response to mechanical stimulus
GO:0051607	defense response to virus
GO:0007252	I-kappaB phosphorylation
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0002282	microglial cell activation during immune response
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity
GO:0032722	positive regulation of chemokine production
GO:0050729	positive regulation of inflammatory response
GO:0045356	positive regulation of interferon-alpha biosynthetic process
GO:0045359	positive regulation of interferon-beta biosynthetic process
GO:0045078	positive regulation of interferon-gamma biosynthetic process
GO:0032755	positive regulation of interleukin-6 production
GO:0045416	positive regulation of interleukin-8 biosynthetic process
GO:0032757	positive regulation of interleukin-8 production
GO:0042346	positive regulation of NF-kappaB import into nucleus
GO:0042221	response to chemical stimulus
GO:0034154	toll-like receptor 7 signaling pathway
GO:0034162	toll-like receptor 9 signaling pathway
GO:0002224	toll-like receptor signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0032009	early phagosome
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0005768	endosome
GO:0010008	endosome membrane
GO:0000139	Golgi membrane
GO:0016021	integral to membrane
GO:0005764	lysosome
GO:0005886	plasma membrane

Molecular Function

GO:0003725	double-stranded RNA binding
GO:0008144	drug binding
GO:0003727	single-stranded RNA binding
GO:0035197	siRNA binding
GO:0004888	transmembrane receptor activity

toll-like receptor 7

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function