ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H

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Synonym

NBP1, ATP6V1H, SFDbeta, lysosomal 50/57kD, Nef-binding protein 1, CGI-11, Vacuolar proton pump subunit SFD, VMA13, SFDalpha, Vacuolar proton pump subunit H, V-ATPase H subunit, Vacuolar ATP synthase subunit H, SFD, V-ATPase 50/57 kDa subunits, MSTP042

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:368.60 cerebellum:818.60 brain stem:- corpus callosum/glia:729 pineal gland:296.70 peripheral nerve:30.70 spine:112.30 retina:- eye:58.80 artery/aorta:149.90 vein:133.30 lymphnode:70.80 peripheral blood:491.90 spleen:170.20 thymus:270.60 bone marrow:137.80 adipose:322.70 bone:153.50 skin:76.80
GeneChip cerebrum:8.51 cerebellum:8.17 brain stem:8.51 corpus callosum/glia:7.02 pineal gland:- peripheral nerve:7.82 spine:7.72 retina:- eye:- artery/aorta:6.97 vein:6.91 lymphnode:6.95 peripheral blood:- spleen:6.86 thymus:7.49 bone marrow:6.57 adipose:7.03 bone:- skin:7.45
CAGE cerebrum:4.45 cerebellum:- brain stem:3.99 corpus callosum/glia:3.61 pineal gland:4.27 peripheral nerve:- spine:3.48 retina:- eye:- artery/aorta:3.44 vein:3.52 lymphnode:3.41 peripheral blood:- spleen:3.23 thymus:3.66 bone marrow:- adipose:3.49 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.18 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.48 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:300.70 placenta:102 prostate:146.40 ovary:74.50 testis:73.50 heart:76.60 muscle:20.10 esophagus:342.80 stomach:318.60 intestine:194.40 colon:59.40     liver/hepato:10.60        lung:88    bladder:251.20 kidney:259.90 pituitary:- thyroid/parathyroid:655 adrenal gland:558.70 pancreas:8.90 breast:83.60 salivary:328.40
GeneChip uterus:7.26 placenta:7.01 prostate:8.13 ovary:7.38 testis:7.45 heart:7.03 muscle:7.47 esophagus:7.53 stomach:6.76 intestine:6.82 colon:6.69 liver/hepato:6.40 lung:7.18 bladder:- kidney:8.18 pituitary:8.07 thyroid/parathyroid:7.91 adrenal gland:7.46 pancreas:6.65 breast:7.29 salivary:7.35
CAGE uterus:3.26 placenta:3.42 prostate:3.36 ovary:3.19 testis:3.50 heart:3.30 muscle:3.23 esophagus:3.51 stomach:- intestine:3.12 colon:3.24     liver/hepato:2.82    lung:3.68 bladder:3.32 kidney:4.05 pituitary:4.20 thyroid/parathyroid:3.86 adrenal gland:- pancreas:2.86 breast:3.54 salivary:3.64
RNA-seq uterus:- placenta:- prostate:3.93 ovary:2.56 testis:2.55 heart:1.37 muscle:2.95 esophagus:- stomach:- intestine:- colon:1.31     liver/hepato:1.05        lung:2.90    bladder:- kidney:3.27 pituitary:- thyroid/parathyroid:3.08 adrenal gland:2.00 pancreas:- breast:2.62 salivary:-

Gene Information

IDs

Refseq ID NM_015941
Gene ID 51606
Unigene ID Hs.491737
Probe set ID 221504_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000047249
GTEx ID ENSG00000047249

Orthologous Gene

Mouse[1]  NM_133826
Rat[1]  NM_001013929

Chromosomal Region

8q11.23  [54,628,117  -  54,756,118]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

2014052
2874839
9442887
9620685
10810093
10931946
11179428
11329013
11463741
11836511
12032142
12058068
12163484
12477932
12539959
12788495
14580332
14597263
14702039
15489334
16103193
16169070
16344560
17897319
18368028
19056867
19815536
20488787
20639865
21139048
21674799
21871445
21890473
21906983
21963094
21987572
21988832
22053931
22360420
22863883
22939629
23000965
23092984
23956138
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006200  ATP catabolic process
GO:0015991  ATP hydrolysis coupled proton transport
GO:0006879  cellular iron ion homeostasis
GO:0006897  endocytosis
GO:0008286  insulin receptor signaling pathway
GO:0051701  interaction with host
GO:0050790  regulation of catalytic activity
GO:0050690  regulation of defense response to virus by virus
GO:0033572  transferrin transport
GO:0055085  transmembrane transport
GO:0007035  vacuolar acidification
GO:0016032  viral reproduction
GO:0019048  virus-host interaction

Cellular Component

GO:0005829  cytosol
GO:0005886  plasma membrane
GO:0000221  vacuolar proton-transporting V-type ATPase, V1 domain

Molecular Function

GO:0016887  ATPase activity
GO:0030234  enzyme regulator activity
GO:0005515  protein binding
GO:0046961  proton-transporting ATPase activity, rotational mechanism