ATPase, class I, type 8B, member 1

Synonym

ATP8B1, FIC1, PFIC1, PFIC, ATPIC, ATPase class I type 8B member 1, Probable phospholipid-transporting ATPase IC, BRIC, ATPase, Class I, type 8B, member 1, Familial intrahepatic cholestasis type 1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:5.90

artery/aorta:30

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:39.40

adipose:-

bone:-

skin:9.60

GeneChip

cerebrum:9.74

cerebellum:10.34

brain stem:9.40

corpus callosum/glia:10.19

pineal gland:-

peripheral nerve:9.87

spine:9.72

retina:-

eye:-

artery/aorta:10

vein:9.42

lymphnode:10.33

peripheral blood:-

spleen:10.49

thymus:10.30

bone marrow:9.61

adipose:9.08

bone:-

skin:9.75

CAGE

cerebrum:0.95

cerebellum:-

brain stem:0.93

corpus callosum/glia:1.23

pineal gland:1.08

peripheral nerve:-

spine:1.21

retina:-

eye:-

artery/aorta:4.03

vein:2.54

lymphnode:1.93

peripheral blood:-

spleen:1.97

thymus:0.86

bone marrow:-

adipose:2.81

bone:-

skin:-

RNA-seq

cerebrum:0.91

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.17

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.39

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:14.60

prostate:33.80

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:42.50

intestine:-

colon:8.50

liver/hepato:10.60

lung:24.40

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:17.80

breast:-

salivary:-

GeneChip

uterus:9.87

placenta:9.38

prostate:9.75

ovary:9.75

testis:9.85

heart:9.14

muscle:8.85

esophagus:9.52

stomach:10.13

intestine:9.15

colon:9.89

liver/hepato:9.97

lung:10.08

bladder:-

kidney:9.78

pituitary:9.93

thyroid/parathyroid:10.41

adrenal gland:10.20

pancreas:7.99

breast:10.17

salivary:9.31

CAGE

uterus:3.32

placenta:2.21

prostate:3.73

ovary:2.51

testis:1.51

heart:2.39

muscle:1.64

esophagus:3.45

stomach:-

intestine:4.42

colon:4.57

liver/hepato:3.01

lung:3.09

bladder:3.92

kidney:2.48

pituitary:1.85

thyroid/parathyroid:3.06

adrenal gland:-

pancreas:4.37

breast:3.02

salivary:4.09

RNA-seq

uterus:-

placenta:-

prostate:4.15

ovary:1.98

testis:1.87

heart:1.30

muscle:0.63

esophagus:-

stomach:-

intestine:-

colon:3.70

liver/hepato:2.38

lung:3.75

bladder:-

kidney:2.75

pituitary:-

thyroid/parathyroid:3.03

adrenal gland:2.43

pancreas:-

breast:2.07

salivary:-

IDs

Refseq ID	NM_005603
Gene ID	5205
Unigene ID	Hs.216623
Probe set ID	214594_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000081923
GTEx ID	ENSG00000081923

Orthologous Gene

Mouse[2]	NM_001001488
Rat[1]	NM_001106140

Chromosomal Region

18q21.31 [55,313,658 - 55,470,327]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001757	ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter
IPR006539	ATPase, P-type, phospholipid-translocating, flippase

GO:0006200	ATP catabolic process
GO:0015721	bile acid and bile salt transport
GO:0008206	bile acid metabolic process
GO:0034220	ion transmembrane transport
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0045332	phospholipid translocation
GO:0055085	transmembrane transport

GO:0016324	apical plasma membrane
GO:0031526	brush border membrane
GO:0005783	endoplasmic reticulum
GO:0005887	integral to plasma membrane
GO:0005886	plasma membrane

GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0019829	cation-transporting ATPase activity
GO:0000287	magnesium ion binding
GO:0004012	phospholipid-translocating ATPase activity
GO:0005515	protein binding

ATPase, class I, type 8B, member 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function