pyruvate kinase, muscle

Synonym

PKM, THBP1, Pyruvate kinase 2/3, PKM2, MGC3932, PK2, Pyruvate kinase muscle isozyme, Cytosolic thyroid hormone-binding protein, pyruvate kinase, muscle, Pyruvate kinase isozymes M1/M2, OIP3, PK3, TCB, CTHBP

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1518.20

cerebellum:1763.10

brain stem:-

corpus callosum/glia:6036.40

pineal gland:1483.50

peripheral nerve:368.10

spine:561.50

retina:1305

eye:1210.70

artery/aorta:1738.60

vein:1599.60

lymphnode:1162.70

peripheral blood:2568.80

spleen:1626

thymus:1082.20

bone marrow:747.90

adipose:1855.40

bone:2942.80

skin:1771.20

GeneChip

cerebrum:9.78

cerebellum:9.82

brain stem:9.85

corpus callosum/glia:8.96

pineal gland:-

peripheral nerve:10.69

spine:9.52

retina:-

eye:-

artery/aorta:9.09

vein:9.24

lymphnode:9.25

peripheral blood:-

spleen:8.62

thymus:8.05

bone marrow:9.31

adipose:8.65

bone:-

skin:9.01

CAGE

cerebrum:6.59

cerebellum:-

brain stem:6.33

corpus callosum/glia:6.05

pineal gland:6.93

peripheral nerve:-

spine:6.04

retina:-

eye:-

artery/aorta:6.27

vein:5.83

lymphnode:6.25

peripheral blood:-

spleen:5.96

thymus:5.56

bone marrow:-

adipose:5.72

bone:-

skin:-

RNA-seq

cerebrum:5.16

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:756.40

placenta:418.90

prostate:766

ovary:1006.10

testis:341.80

heart:894

muscle:1547

esophagus:1371.30

stomach:828.40

intestine:1133.90

colon:1755.30

liver/hepato:137.20

lung:610.90

bladder:753.70

kidney:1289.20

pituitary:116

thyroid/parathyroid:2947.40

adrenal gland:2183.80

pancreas:302.30

breast:1208.10

salivary:985.20

GeneChip

uterus:8.74

placenta:8.16

prostate:8.83

ovary:9

testis:9.28

heart:9.51

muscle:10.09

esophagus:9.96

stomach:8.55

intestine:8.93

colon:8.54

liver/hepato:6.14

lung:8.92

bladder:-

kidney:9.54

pituitary:9.15

thyroid/parathyroid:8.90

adrenal gland:9.47

pancreas:7.48

breast:9.36

salivary:8.94

CAGE

uterus:5.64

placenta:5.78

prostate:5.75

ovary:5.59

testis:5.98

heart:6.60

muscle:6.90

esophagus:6.33

stomach:-

intestine:5.68

colon:5.68

liver/hepato:3.77

lung:5.91

bladder:5.86

kidney:6.62

pituitary:5.54

thyroid/parathyroid:5.50

adrenal gland:-

pancreas:5.02

breast:6.35

salivary:6.27

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.00

testis:0.00

heart:4.21

muscle:5.24

esophagus:-

stomach:-

intestine:-

colon:1.80

liver/hepato:0.00

lung:0.00

bladder:-

kidney:0.00

pituitary:-

thyroid/parathyroid:0.00

adrenal gland:0.00

pancreas:-

breast:0.19

salivary:-

IDs

Refseq ID	NM_182471
Gene ID	5315
Unigene ID	Hs.534770
Probe set ID	201251_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000067225
GTEx ID	ENSG00000067225

Orthologous Gene

Mouse[1]	NM_011099
Rat[1]	NM_011099

Chromosomal Region

15q23 [72,491,370 - 72,524,163]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001697

Pyruvate kinase

Gene Ontology (GO ID)

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006006	glucose metabolic process
GO:0006096	glycolysis
GO:0012501	programmed cell death

Cellular Component

GO:0005929	cilium
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0070062	extracellular vesicular exosome
GO:0005739	mitochondrion
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0000287	magnesium ion binding
GO:0030955	potassium ion binding
GO:0005515	protein binding
GO:0004743	pyruvate kinase activity

pyruvate kinase, muscle

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function