phospholipase A2, group IB (pancreas)

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Synonym

Phospholipase A2 precursor, MGC119834, Group IB phospholipase A2, PLA2A, MGC119835, phospholipase A2, group IB (pancreas), PLA2G1B, PPLA2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.37 cerebellum:3.43 brain stem:3.37 corpus callosum/glia:3.34 pineal gland:- peripheral nerve:3.34 spine:3.27 retina:- eye:- artery/aorta:3.49 vein:3.38 lymphnode:3.25 peripheral blood:- spleen:3.49 thymus:3.13 bone marrow:3.44 adipose:3.33 bone:- skin:3.45
CAGE cerebrum:0.08 cerebellum:- brain stem:0 corpus callosum/glia:0.07 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:2.96 vein:0.34 lymphnode:0 peripheral blood:- spleen:0 thymus:0.06 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.04 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.26 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:40.10 prostate:- ovary:37.30 testis:4.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.18 placenta:3.42 prostate:3.14 ovary:3.56 testis:3.84 heart:3.36 muscle:3.42 esophagus:3.29 stomach:3.38 intestine:7.98 colon:3.46 liver/hepato:3.31 lung:4.30 bladder:- kidney:3.39 pituitary:3.45 thyroid/parathyroid:3.25 adrenal gland:3.72 pancreas:13.31 breast:3.30 salivary:3.25
CAGE uterus:0.95 placenta:0 prostate:0 ovary:0.47 testis:1.32 heart:0.23 muscle:0 esophagus:0 stomach:- intestine:0.07 colon:0.08     liver/hepato:0.14    lung:4.07 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:11.57 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.35 ovary:2.44 testis:1.33 heart:0.15 muscle:0 esophagus:- stomach:- intestine:- colon:0.14     liver/hepato:0.42        lung:3.16    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0.21 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_000928
Gene ID 5319
Unigene ID Hs.99231
Probe set ID 206311_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000170890
GTEx ID ENSG00000170890

Orthologous Gene

Mouse[2]  NM_011107
Rat [0]  

Chromosomal Region

12q24.31  [120,759,914  -  120,765,592]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1918029
2052621
3028739
6349696
6477929
7060561
7584826
7590434
7721806
8175726
8300559
8358438
9188469
9377118
9745929
9847074
9848887
9886417
10509674
10551547
10735945
10873103
10905638
10964913
11025364
11353443
11510783
11807183
11851982
12423354
12477932
12759552
12860195
14557262
14998370
15220446
15489334
15528384
15736947
16005851
16391564
16392040
16495221
16541075
16567514
17065600
17223797
17434532
17470210
17488462
17981679
18212756
18492292
18636547
19297324
19913121
20536387
20628086
21988832
22528125
22680611
24441870

Gene Ontology  (GO ID)

Biological Process

GO:0007015  actin filament organization
GO:0000187  activation of MAPK activity
GO:0032431  activation of phospholipase A2 activity
GO:0050482  arachidonic acid secretion
GO:0032869  cellular response to insulin stimulus
GO:0006633  fatty acid biosynthetic process
GO:0015758  glucose transport
GO:0046474  glycerophospholipid biosynthetic process
GO:0032637  interleukin-8 production
GO:0019370  leukotriene biosynthetic process
GO:0044240  multicellular organismal lipid catabolic process
GO:0030593  neutrophil chemotaxis
GO:0002446  neutrophil mediated immunity
GO:0006654  phosphatidic acid biosynthetic process
GO:0046470  phosphatidylcholine metabolic process
GO:0006644  phospholipid metabolic process
GO:0010524  positive regulation of calcium ion transport into cytosol
GO:0045740  positive regulation of DNA replication
GO:0048146  positive regulation of fibroblast proliferation
GO:0050778  positive regulation of immune response
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0050714  positive regulation of protein secretion
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0007243  protein kinase cascade
GO:0007165  signal transduction

Cellular Component

GO:0009986  cell surface
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0030141  secretory granule

Molecular Function

GO:0032052  bile acid binding
GO:0005509  calcium ion binding
GO:0047498  calcium-dependent phospholipase A2 activity
GO:0004623  phospholipase A2 activity
GO:0005102  receptor binding