phospholipase C, gamma 1

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Synonym

phospholipase Cgamma1, PLCG1, PLC148, Phospholipase C-gamma-1, PLC-gamma-1, PLC-II, PLC-148, phospholipase C, gamma 1, PLC1, PLCgamma1

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:45 cerebellum:75.60 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:61.30 spine:112.30 retina:- eye:88.20 artery/aorta:- vein:- lymphnode:91 peripheral blood:18.20 spleen:- thymus:193.30 bone marrow:59 adipose:40.30 bone:38.40 skin:62.40
GeneChip cerebrum:7.09 cerebellum:7.45 brain stem:6.97 corpus callosum/glia:7.32 pineal gland:- peripheral nerve:6.97 spine:7.02 retina:- eye:- artery/aorta:7.45 vein:7.19 lymphnode:7.73 peripheral blood:- spleen:7.33 thymus:8.10 bone marrow:6.52 adipose:7.25 bone:- skin:7.08
CAGE cerebrum:3.92 cerebellum:- brain stem:3.76 corpus callosum/glia:4.01 pineal gland:3.18 peripheral nerve:- spine:3.82 retina:- eye:- artery/aorta:3.87 vein:4.35 lymphnode:3.77 peripheral blood:- spleen:3.27 thymus:4.56 bone marrow:- adipose:3.78 bone:- skin:-
RNA-seq cerebrum:0.78 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.72 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.84 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:40.10 prostate:11.30 ovary:186.30 testis:47.60 heart:25.50 muscle:40.20 esophagus:- stomach:63.70 intestine:32.40 colon:195     liver/hepato:-        lung:63.50    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:163.70 adrenal gland:- pancreas:- breast:18.60 salivary:-
GeneChip uterus:7.29 placenta:6.81 prostate:6.77 ovary:6.94 testis:7.33 heart:7.15 muscle:6.28 esophagus:6.82 stomach:6.93 intestine:6.80 colon:6.97 liver/hepato:6.46 lung:7.47 bladder:- kidney:6.87 pituitary:6.77 thyroid/parathyroid:7.36 adrenal gland:7.17 pancreas:6.41 breast:7.25 salivary:6.59
CAGE uterus:3.91 placenta:2.73 prostate:3.55 ovary:3.44 testis:3.48 heart:3.55 muscle:3.06 esophagus:3.31 stomach:- intestine:3.30 colon:3.56     liver/hepato:2.33    lung:3.61 bladder:3.42 kidney:2.90 pituitary:3.02 thyroid/parathyroid:3.53 adrenal gland:- pancreas:2.08 breast:4.39 salivary:3.03
RNA-seq uterus:- placenta:- prostate:2.42 ovary:1.21 testis:2.59 heart:0.34 muscle:0.77 esophagus:- stomach:- intestine:- colon:2.18     liver/hepato:0.00        lung:2.38    bladder:- kidney:1.75 pituitary:- thyroid/parathyroid:2.02 adrenal gland:2.27 pancreas:- breast:1.48 salivary:-

IDs

Refseq ID NM_182811
Gene ID 5335
Unigene ID Hs.268177
Probe set ID 202789_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000124181
GTEx ID ENSG00000124181

Orthologous Gene

Mouse[1]  NM_021280
Rat[1]  NM_013187

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

1383690
1500851
1501243
1639386
1676673
1683701
1689310
1715690
1979339
2167438
2173144
2176151
2550068
3254788
7510703
7512571
7513258
7518429
7535778
7536744
7589147
7592796
7629168
7657612
7681365
7682059
7689724
7761838
7774645
7799925
7831290
7876130
7999363
8084603
8155326
8290562
8384556
8386518
8388538
8443409
8596638
8627166
8628282
8649391
8657103
8660853
8662733
8672127
8805332
8824280
8885868
8890167
8892607
8905292
8906806
8910519
8918464
8977179
8995379
9045636
9045685
9047383
9164868
9174053
9178760
9207933
9231720
9234717
9278385
9281317
9299537
9314836
9341187
9344703
9344857
9398617
9489702
9516477
9535722
9600074
9632142
9632636
9660748
9697839
9712732
9729044
9730685
9743338
9756944
9808187
9819383
9846481
9856458
9891995
10022833
10092678
10350061
10391903
10430888
10455176
10467411
10473113
10488157
10501179
10579907
10586033
10652211
10652257
10684856
10692392
10708759
10770799
10783152
10811803
10823839
10843712
10873601
10899172
10913276
10926122
10940929
10980614
11043766
11048639
11071635
11094073
11259588
11312102
11353454
11368773
11390470
11390650
11409699
11507676
11779129
11780052
11823862
11886851
11888936
11941371
11956228
11960376
12061819
12071848
12074588
12084069
12085993
12163161
12419535
12454018
12477932
12482669
12496421
12507498
12514734
12598525
12601080
12646582
12771140
12788694
12803489
12845332
12890670
12898421
12937273
12941616
12960351
13129935
14523024
14568990
14647465
14702343
14722116
14744865
14968112
14978237
14989173
15062102
15117958
15123640
15144186
15153499
15161916
15184383
15252117
15270728
15329338
15488758
15556869
15563458
15592455
15623534
15644415
15654973
15696170
15702972
15744307
15766521
15872086
15944397
15951569
15953601
15972651
15996687
16153436
16273093
16341594
16467851
16503409
16764945
16767099
16921170
16938345
17023658
17081983
17111345
17130290
17148460
17229814
17242406
17336371
17372230
17419608
17474147
17561374
17561467
17562871
17991733
18037957
18256683
18292392
18467332
18579528
18594017
18596081
18671761
19018007
19074886
19086053
19179337
19223396
19570985
19586919
19663908
19681907
19710135
19711039
19712589
19805522
19881535
19913121
19915061
19952372
20011604
20041213
20056178
20080774
20232348
20336759
20379146
20510673
20514023
20621058
20628086
20674545
20872577
20889506
21087080
21139048
21176845
21209106
21233200
21242968
21285289
21360263
21705626
21762810
21798286
21875593
21890473
21906983
21986528
22022282
22262199
22454520
22474331
22554284
22749651
22837484
22847294
22863883
22939629
22974441
23000965
23061666
23063561
23063587
23703528
23925006
23986795
24250222
24440983
24497536
24502564
24633157
24797263
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0000186  activation of MAPKK activity
GO:0007202  activation of phospholipase C activity
GO:0007411  axon guidance
GO:0007596  blood coagulation
GO:0071364  cellular response to epidermal growth factor stimulus
GO:0019221  cytokine-mediated signaling pathway
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0001701  in utero embryonic development
GO:0045087  innate immune response
GO:0043647  inositol phosphate metabolic process
GO:0050900  leukocyte migration
GO:0048011  nerve growth factor receptor signaling pathway
GO:0009395  phospholipid catabolic process
GO:0045766  positive regulation of angiogenesis
GO:0043536  positive regulation of blood vessel endothelial cell migration
GO:0010634  positive regulation of epithelial cell migration
GO:0007165  signal transduction
GO:0050852  T cell receptor signaling pathway
GO:0019048  virus-host interaction

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0030027  lamellipodium
GO:0005886  plasma membrane
GO:0001726  ruffle
GO:0008180  signalosome

Molecular Function

GO:0005509  calcium ion binding
GO:0035254  glutamate receptor binding
GO:0005168  neurotrophin TRKA receptor binding
GO:0004435  phosphoinositide phospholipase C activity
GO:0004629  phospholipase C activity
GO:0005543  phospholipid binding
GO:0005515  protein binding
GO:0005057  receptor signaling protein activity
GO:0030971  receptor tyrosine kinase binding