two pore segment channel 1

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Synonym

TPCN1, KIAA1169, two pore segment channel 1, FLJ20612, TPC1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:56.90 cerebellum:75.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:135.20 artery/aorta:- vein:- lymphnode:91 peripheral blood:36.40 spleen:18.90 thymus:25.80 bone marrow:78.70 adipose:40.30 bone:76.80 skin:91.20
GeneChip cerebrum:8.03 cerebellum:8.82 brain stem:8.23 corpus callosum/glia:8.29 pineal gland:- peripheral nerve:8.37 spine:8.09 retina:- eye:- artery/aorta:8.34 vein:7.76 lymphnode:8.23 peripheral blood:- spleen:7.93 thymus:6.77 bone marrow:6.83 adipose:7.82 bone:- skin:7.87
CAGE cerebrum:4.25 cerebellum:- brain stem:4.65 corpus callosum/glia:4.63 pineal gland:4.19 peripheral nerve:- spine:4.26 retina:- eye:- artery/aorta:4.40 vein:3.83 lymphnode:3.91 peripheral blood:- spleen:3.48 thymus:2.84 bone marrow:- adipose:4.04 bone:- skin:-
RNA-seq cerebrum:0.45 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.56 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:91.10 prostate:78.90 ovary:74.50 testis:51.90 heart:12.80 muscle:40.20 esophagus:- stomach:106.20 intestine:129.60 colon:110.20     liver/hepato:10.60        lung:24.40    bladder:251.20 kidney:249.50 pituitary:- thyroid/parathyroid:- adrenal gland:101.60 pancreas:35.60 breast:46.50 salivary:-
GeneChip uterus:7.77 placenta:7.56 prostate:7.75 ovary:7.93 testis:7.35 heart:8.34 muscle:7.65 esophagus:8.45 stomach:7.63 intestine:7.83 colon:8.01 liver/hepato:7.68 lung:8.17 bladder:- kidney:9.12 pituitary:8.43 thyroid/parathyroid:8.81 adrenal gland:8.94 pancreas:7.70 breast:8.18 salivary:8.26
CAGE uterus:4.33 placenta:3.83 prostate:3.97 ovary:3.96 testis:3.56 heart:4.09 muscle:3.50 esophagus:3.84 stomach:- intestine:4.13 colon:4.17     liver/hepato:3.20    lung:3.69 bladder:4.09 kidney:4.22 pituitary:4.31 thyroid/parathyroid:4.12 adrenal gland:- pancreas:4.42 breast:3.71 salivary:4.68
RNA-seq uterus:- placenta:- prostate:1.51 ovary:0.78 testis:0.70 heart:1.31 muscle:0.89 esophagus:- stomach:- intestine:- colon:0.34     liver/hepato:0.19        lung:0.74    bladder:- kidney:0.26 pituitary:- thyroid/parathyroid:1.48 adrenal gland:0.00 pancreas:- breast:1.23 salivary:-

Gene Information

IDs

Refseq ID NM_001143819
Gene ID 53373
Unigene ID Hs.524763
Probe set ID 217914_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000186815
GTEx ID ENSG00000186815

Orthologous Gene

Mouse[3]  NM_145853
Rat [0]  

Chromosomal Region

12q24.13  [113,658,855  -  113,736,390]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10574461
10753632
12168954
12477932
14702039
16344560
16382101
19387438
19620632
22270358
22500018
23149075
24776928

Gene Ontology  (GO ID)

Biological Process

GO:0034220  ion transmembrane transport
GO:0055085  transmembrane transport

Cellular Component

GO:0010008  endosome membrane
GO:0016021  integral to membrane
GO:0005765  lysosomal membrane

Molecular Function

GO:0042802  identical protein binding
GO:0005515  protein binding
GO:0005244  voltage-gated ion channel activity