exosome component 4

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Synonym

exosome component 4, Rrp41p, p12A, FLJ20591, hRrp41p, Ribosomal RNA-processing protein 41, EXOSC4, Ski6p, Exosome component 4, RRP41A, SKI6, Exosome complex exonuclease RRP41, RRP41

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:14.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:47 artery/aorta:30 vein:- lymphnode:- peripheral blood:18.20 spleen:18.90 thymus:- bone marrow:39.40 adipose:- bone:12.80 skin:-
GeneChip cerebrum:6.32 cerebellum:6.39 brain stem:6.40 corpus callosum/glia:6.17 pineal gland:- peripheral nerve:6.32 spine:6.24 retina:- eye:- artery/aorta:6.50 vein:6.46 lymphnode:6.29 peripheral blood:- spleen:6.08 thymus:6.26 bone marrow:6.41 adipose:6.29 bone:- skin:6.86
CAGE cerebrum:2.68 cerebellum:- brain stem:2.58 corpus callosum/glia:2.54 pineal gland:2.27 peripheral nerve:- spine:2.31 retina:- eye:- artery/aorta:2.26 vein:2.25 lymphnode:2.46 peripheral blood:- spleen:2.71 thymus:2.66 bone marrow:- adipose:2.12 bone:- skin:-
RNA-seq cerebrum:2.74 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.83 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.17 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:- prostate:11.30 ovary:37.30 testis:38.90 heart:- muscle:80.40 esophagus:- stomach:- intestine:- colon:25.40     liver/hepato:10.60        lung:4.90    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.47 placenta:6.63 prostate:6.66 ovary:6.55 testis:8.17 heart:6.37 muscle:6.26 esophagus:6.89 stomach:6.42 intestine:6.50 colon:6.53 liver/hepato:6.52 lung:6.13 bladder:- kidney:6.79 pituitary:6.40 thyroid/parathyroid:6.37 adrenal gland:6.59 pancreas:6.73 breast:6.79 salivary:6.93
CAGE uterus:2.16 placenta:2.54 prostate:2.45 ovary:2.49 testis:3.49 heart:2.42 muscle:2.49 esophagus:2.52 stomach:- intestine:2.19 colon:2.60     liver/hepato:2.98    lung:2.19 bladder:2.35 kidney:2.78 pituitary:2.27 thyroid/parathyroid:2.48 adrenal gland:- pancreas:2.71 breast:1.92 salivary:2.80
RNA-seq uterus:- placenta:- prostate:3.20 ovary:3.51 testis:4.85 heart:2.18 muscle:2.57 esophagus:- stomach:- intestine:- colon:3.06     liver/hepato:3.50        lung:2.49    bladder:- kidney:3.70 pituitary:- thyroid/parathyroid:3.33 adrenal gland:3.63 pancreas:- breast:3.39 salivary:-

Gene Information

IDs

Refseq ID NM_019037
Gene ID 54512
Unigene ID Hs.632041
Probe set ID 58696_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000178896
GTEx ID ENSG00000178896

Orthologous Gene

Mouse[4]  NM_175399
Rat [0]  

Chromosomal Region

8q24.3  [145,133,529  -  145,135,550]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10465791
11110791
11719186
11790298
11812149
11879549
12419256
12477932
12788944
14527413
14702039
15231747
15489334
15635413
16341674
16912217
17174896
17545563
18172165
20531386
20531389
21139048
21182203
21255825
22863883
22939629
23000965
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0051607  defense response to virus
GO:0045006  DNA deamination
GO:0043928  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
GO:0010467  gene expression
GO:0071044  histone mRNA catabolic process
GO:0000460  maturation of 5.8S rRNA
GO:0016071  mRNA metabolic process
GO:0071028  nuclear mRNA surveillance
GO:0000956  nuclear-transcribed mRNA catabolic process
GO:0000288  nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0030307  positive regulation of cell growth
GO:0016070  RNA metabolic process
GO:0006364  rRNA processing

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0000178  exosome (RNase complex)
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0000175  3'-5'-exoribonuclease activity
GO:0017091  AU-rich element binding
GO:0004532  exoribonuclease activity
GO:0005515  protein binding