POU class 5 homeobox 1B

 jump to detail

Synonym

-

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:4.80
GeneChip cerebrum:6.71 cerebellum:7.07 brain stem:6.67 corpus callosum/glia:6.82 pineal gland:- peripheral nerve:6.67 spine:6.57 retina:- eye:- artery/aorta:6.80 vein:6.92 lymphnode:6.73 peripheral blood:- spleen:6.58 thymus:6.74 bone marrow:6.82 adipose:6.84 bone:- skin:6.71
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.11 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.11 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:- salivary:-
GeneChip uterus:6.90 placenta:6.59 prostate:6.51 ovary:6.94 testis:6.41 heart:6.84 muscle:7.02 esophagus:6.79 stomach:6.93 intestine:6.93 colon:6.72 liver/hepato:6.80 lung:6.81 bladder:- kidney:6.96 pituitary:6.81 thyroid/parathyroid:6.83 adrenal gland:6.67 pancreas:7.07 breast:6.67 salivary:6.80
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.44 ovary:0.19 testis:0.24 heart:0.22 muscle:0 esophagus:- stomach:- intestine:- colon:0.26     liver/hepato:0.04        lung:0.20    bladder:- kidney:1.68 pituitary:- thyroid/parathyroid:0.29 adrenal gland:0.39 pancreas:- breast:0.20 salivary:-

Gene Information

IDs

Refseq ID NM_001159542
Gene ID 5462
Unigene ID Hs.450254
Probe set ID 214532_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000212993
GTEx ID ENSG00000212993

Orthologous Gene

Mouse[1]  NM_013633
Rat[1]  NM_013633

Chromosomal Region

8q24.21  [128,427,133  -  128,429,455]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

1408763
11780052
16201836
16229821
17401363
17401366
17618283
17618284
18372901
18946985
18949397
19562729
20017164
20062064
20158306
22041458
23064289
23933063
24292274
24338422

Gene Ontology  (GO ID)

Biological Process

GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity