DIRAS family, GTP-binding RAS-like 2

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Synonym

DKFZp761C07121, DIRAS2, GTP-binding protein Di-Ras2, DIRAS family, GTP-binding RAS-like 2, Di-Ras2, Distinct subgroup of the Ras family member 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:314.10 cerebellum:1234.20 brain stem:- corpus callosum/glia:58.30 pineal gland:148.30 peripheral nerve:- spine:- retina:- eye:70.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:7.37 cerebellum:9.31 brain stem:6.25 corpus callosum/glia:4.03 pineal gland:- peripheral nerve:5.29 spine:5.99 retina:- eye:- artery/aorta:2.71 vein:2.45 lymphnode:2.51 peripheral blood:- spleen:2.29 thymus:2.44 bone marrow:2.66 adipose:2.40 bone:- skin:2.50
CAGE cerebrum:4.36 cerebellum:- brain stem:2.95 corpus callosum/glia:2.94 pineal gland:3.35 peripheral nerve:- spine:3.09 retina:- eye:- artery/aorta:0.87 vein:0.18 lymphnode:0.37 peripheral blood:- spleen:0.09 thymus:0.57 bone marrow:- adipose:0.63 bone:- skin:-
RNA-seq cerebrum:5.92 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.17 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.06 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:- prostate:11.30 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:4.90    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:27.90 salivary:-
GeneChip uterus:2.54 placenta:2.59 prostate:2.46 ovary:2.38 testis:2.38 heart:2.46 muscle:2.47 esophagus:2.56 stomach:2.50 intestine:2.68 colon:2.49 liver/hepato:2.47 lung:2.31 bladder:- kidney:2.65 pituitary:3.07 thyroid/parathyroid:3.40 adrenal gland:2.59 pancreas:2.60 breast:2.46 salivary:3.49
CAGE uterus:0.84 placenta:1.35 prostate:0.62 ovary:0 testis:0.19 heart:0.03 muscle:0.21 esophagus:0.18 stomach:- intestine:1.61 colon:0.60     liver/hepato:0.55    lung:0.35 bladder:1.02 kidney:0.88 pituitary:0.69 thyroid/parathyroid:1.45 adrenal gland:- pancreas:1.42 breast:0.55 salivary:2.50
RNA-seq uterus:- placenta:- prostate:0.55 ovary:0.06 testis:0.12 heart:0.06 muscle:0 esophagus:- stomach:- intestine:- colon:0.69     liver/hepato:0.13        lung:0.00    bladder:- kidney:0.65 pituitary:- thyroid/parathyroid:0.71 adrenal gland:0.03 pancreas:- breast:0.12 salivary:-

Gene Information

IDs

Refseq ID NM_017594
Gene ID 54769
Unigene ID Hs.165636
Probe set ID 219619_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000165023
GTEx ID ENSG00000165023

Orthologous Gene

Mouse[1]  NM_001024474
Rat [0]  

Chromosomal Region

9q22.2  [93,372,114  -  93,405,386]

Gene Family (Interpro ID)

IPR013753  Ras
IPR001806  Ras GTPase
IPR020849  Ras small GTPase
IPR003579  Ras small GTPase, Rab type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR003578  Small GTPase, Rho type

Link to Pubmed  (Pubmed ID)

12194967
12477932
14702039
15164053
15489334
17207965
17500595
17903297
18464913
20379614
21139048
21750579
21890473

Gene Ontology  (GO ID)

Biological Process

GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005886  plasma membrane

Molecular Function

GO:0005525  GTP binding
GO:0003924  GTPase activity