ubiquitin specific peptidase 47

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Synonym

Ubiquitin thioesterase 47, Ubiquitin carboxyl-terminal hydrolase 47, TRFP, FLJ20727, Deubiquitinating enzyme 47, ubiquitin specific protease 47, Ubiquitin-specific-processing protease 47, USP47, ubiquitin specific peptidase 47

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:78.20 cerebellum:12.60 brain stem:- corpus callosum/glia:58.30 pineal gland:148.30 peripheral nerve:429.40 spine:224.60 retina:118.60 eye:111.70 artery/aorta:179.90 vein:133.30 lymphnode:80.90 peripheral blood:91.10 spleen:18.90 thymus:38.70 bone marrow:78.70 adipose:80.70 bone:64 skin:96
GeneChip cerebrum:7.88 cerebellum:7.53 brain stem:8.13 corpus callosum/glia:8.40 pineal gland:- peripheral nerve:8.05 spine:7.78 retina:- eye:- artery/aorta:8.28 vein:7.86 lymphnode:8.05 peripheral blood:- spleen:7.92 thymus:8.29 bone marrow:7.20 adipose:7.88 bone:- skin:7.86
CAGE cerebrum:3.96 cerebellum:- brain stem:4.07 corpus callosum/glia:3.85 pineal gland:4.44 peripheral nerve:- spine:4.24 retina:- eye:- artery/aorta:3.79 vein:3.50 lymphnode:3.55 peripheral blood:- spleen:3.62 thymus:4.17 bone marrow:- adipose:3.78 bone:- skin:-
RNA-seq cerebrum:4.14 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.15 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.54 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:72.90 placenta:87.40 prostate:157.70 ovary:- testis:64.90 heart:63.90 muscle:200.90 esophagus:342.80 stomach:85 intestine:64.80 colon:17     liver/hepato:116.10        lung:132    bladder:- kidney:145.60 pituitary:116 thyroid/parathyroid:- adrenal gland:50.80 pancreas:35.60 breast:37.20 salivary:-
GeneChip uterus:8.24 placenta:7.51 prostate:8.39 ovary:8 testis:7.84 heart:8.16 muscle:8.58 esophagus:8.36 stomach:8.08 intestine:7.27 colon:6.32 liver/hepato:8.55 lung:7.98 bladder:- kidney:7.32 pituitary:8.41 thyroid/parathyroid:8 adrenal gland:8.47 pancreas:7 breast:8.04 salivary:7.33
CAGE uterus:3.94 placenta:4.09 prostate:3.79 ovary:3.84 testis:3.58 heart:4.14 muscle:4.84 esophagus:3.74 stomach:- intestine:3.69 colon:3.73     liver/hepato:3.83    lung:4.07 bladder:4.10 kidney:3.52 pituitary:4.43 thyroid/parathyroid:3.39 adrenal gland:- pancreas:3.45 breast:3.89 salivary:3.45
RNA-seq uterus:- placenta:- prostate:3.77 ovary:4.04 testis:4.04 heart:3.79 muscle:4.69 esophagus:- stomach:- intestine:- colon:3.73     liver/hepato:3.03        lung:3.70    bladder:- kidney:3.33 pituitary:- thyroid/parathyroid:4.37 adrenal gland:3.49 pancreas:- breast:3.51 salivary:-

Gene Information

IDs

Refseq ID NM_017944
Gene ID 55031
Unigene ID Hs.577256
Probe set ID 221518_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000170242
GTEx ID ENSG00000170242

Orthologous Gene

Mouse[2]  NM_133758, NM_177249
Rat[1]  NM_001107542, NM_177249

Chromosomal Region

11p15.3  [11,862,970  -  11,980,870]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8125298
12477932
12838346
14576168
14638676
14702039
14715245
15302935
15489334
16344560
16964243
17893145
19615732
19966869
20360068
21139048
21362556
21890473
21906983
22017875
22118674
22586326
22863883
22952844
23000965
23752268
23904609
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006284  base-excision repair
GO:0034644  cellular response to UV
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0010972  negative regulation of G2/M transition of mitotic cell cycle
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0030307  positive regulation of cell growth
GO:0006974  response to DNA damage stimulus
GO:0042493  response to drug
GO:0006511  ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0019005  SCF ubiquitin ligase complex

Molecular Function

GO:0005515  protein binding
GO:0004221  ubiquitin thiolesterase activity
GO:0004843  ubiquitin-specific protease activity