GTPase, IMAP family member 5

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Synonym

GIMAP5, Immunity-associated nucleotide 4-like 1 protein, IAN4L1, IAN-5, HIMAP3, IAN5, GTPase, IMAP family member 5, IMAP3, FLJ11296, IAN4, hIAN5, Immunity-associated protein 3, immune associated nucleotide 4 like 1 (mouse)

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.63 cerebellum:6.71 brain stem:6.59 corpus callosum/glia:6.77 pineal gland:- peripheral nerve:7.05 spine:6.86 retina:- eye:- artery/aorta:7.50 vein:7.66 lymphnode:8.40 peripheral blood:- spleen:8.32 thymus:6.92 bone marrow:7.16 adipose:8.12 bone:- skin:7.12
CAGE cerebrum:0.73 cerebellum:- brain stem:0.92 corpus callosum/glia:0.82 pineal gland:1.18 peripheral nerve:- spine:1.19 retina:- eye:- artery/aorta:1.43 vein:2.11 lymphnode:2.47 peripheral blood:- spleen:2.19 thymus:0.91 bone marrow:- adipose:1.69 bone:- skin:-
RNA-seq cerebrum:2.62 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.57 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.69 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:7.25 placenta:7.29 prostate:6.61 ovary:7.16 testis:6.32 heart:7.60 muscle:7.03 esophagus:7.15 stomach:7.20 intestine:7.27 colon:7.38 liver/hepato:7.21 lung:8.44 bladder:- kidney:7.05 pituitary:6.79 thyroid/parathyroid:7.28 adrenal gland:6.91 pancreas:7.25 breast:7.67 salivary:6.60
CAGE uterus:1.33 placenta:1.27 prostate:1.14 ovary:0.95 testis:0.55 heart:1.53 muscle:0.59 esophagus:1.08 stomach:- intestine:1.13 colon:1.43     liver/hepato:1.12    lung:2.12 bladder:1.09 kidney:1.30 pituitary:0.66 thyroid/parathyroid:1.17 adrenal gland:- pancreas:0.58 breast:1.68 salivary:0
RNA-seq uterus:- placenta:- prostate:3.79 ovary:2.66 testis:3.39 heart:3.28 muscle:2.28 esophagus:- stomach:- intestine:- colon:3.38     liver/hepato:3.63        lung:5.79    bladder:- kidney:3.81 pituitary:- thyroid/parathyroid:3.76 adrenal gland:6.03 pancreas:- breast:3.95 salivary:-

Gene Information

IDs

Refseq ID NM_018384
Gene ID 55340
Unigene ID Hs.647079
Probe set ID 64064_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000196329
GTEx ID ENSG00000196329

Orthologous Gene

Mouse[2]  NM_031247, NM_175035
Rat[2]  NM_001033913, NM_145680

Chromosomal Region

7q36.1  [150,419,341  -  150,447,121]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

11238997
11814688
11964296
12477932
12690205
12925764
14702039
14724691
15474311
15489334
17220214
17369194
17641683
19762377
20190135
20237496
20817506
21832049
22190034
22505724
23098229
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0043011  myeloid dendritic cell differentiation
GO:0043066  negative regulation of apoptosis
GO:0032689  negative regulation of interferon-gamma production
GO:0050995  negative regulation of lipid catabolic process
GO:0045019  negative regulation of nitric oxide biosynthetic process
GO:0050868  negative regulation of T cell activation
GO:0010524  positive regulation of calcium ion transport into cytosol
GO:0032831  positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0045588  positive regulation of gamma-delta T cell differentiation
GO:0002925  positive regulation of humoral immune response mediated by circulating immunoglobulin
GO:0045838  positive regulation of membrane potential
GO:0002729  positive regulation of natural killer cell cytokine production
GO:0045954  positive regulation of natural killer cell mediated cytotoxicity
GO:0046902  regulation of mitochondrial membrane permeability
GO:0030217  T cell differentiation
GO:0043029  T cell homeostasis
GO:0001659  temperature homeostasis

Cellular Component

GO:0016021  integral to membrane
GO:0005764  lysosome
GO:0005741  mitochondrial outer membrane

Molecular Function

GO:0005525  GTP binding