DEP domain containing 1

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Synonym

DEP.8, FLJ20354, DEPDC1, SDP35, DEP domain containing 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:- brain stem:- corpus callosum/glia:116.60 pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:5.90 artery/aorta:- vein:133.30 lymphnode:111.20 peripheral blood:- spleen:- thymus:12.90 bone marrow:- adipose:- bone:12.80 skin:4.80
GeneChip cerebrum:3.77 cerebellum:3.79 brain stem:3.70 corpus callosum/glia:3.92 pineal gland:- peripheral nerve:3.68 spine:3.83 retina:- eye:- artery/aorta:3.68 vein:3.68 lymphnode:3.96 peripheral blood:- spleen:3.75 thymus:5.25 bone marrow:5.34 adipose:3.67 bone:- skin:3.51
CAGE cerebrum:0.19 cerebellum:- brain stem:0.09 corpus callosum/glia:0.07 pineal gland:0.14 peripheral nerve:- spine:0.17 retina:- eye:- artery/aorta:0.34 vein:1.23 lymphnode:0.85 peripheral blood:- spleen:1.26 thymus:2.99 bone marrow:- adipose:0.71 bone:- skin:-
RNA-seq cerebrum:0.15 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.19 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.08 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:3.60 prostate:- ovary:- testis:64.90 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:42.20        lung:9.80    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip uterus:3.70 placenta:4.29 prostate:4.27 ovary:3.50 testis:5.80 heart:3.79 muscle:4.06 esophagus:4.14 stomach:4.19 intestine:3.83 colon:3.90 liver/hepato:3.92 lung:3.62 bladder:- kidney:3.90 pituitary:3.72 thyroid/parathyroid:3.83 adrenal gland:3.75 pancreas:4.19 breast:3.77 salivary:3.75
CAGE uterus:0.27 placenta:1.86 prostate:0.39 ovary:0.14 testis:2.93 heart:0.27 muscle:0.05 esophagus:1.72 stomach:- intestine:1.33 colon:1.79     liver/hepato:0.14    lung:0.54 bladder:0 kidney:0.21 pituitary:0 thyroid/parathyroid:0.17 adrenal gland:- pancreas:0 breast:0.90 salivary:0
RNA-seq uterus:- placenta:- prostate:0.15 ovary:0.11 testis:0.00 heart:0.17 muscle:0 esophagus:- stomach:- intestine:- colon:0.12     liver/hepato:0.02        lung:0.09    bladder:- kidney:0.15 pituitary:- thyroid/parathyroid:0.05 adrenal gland:0.06 pancreas:- breast:0.20 salivary:-

Gene Information

IDs

Refseq ID NM_017779
Gene ID 55635
Unigene ID Hs.445098
Probe set ID 220295_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000024526
GTEx ID ENSG00000024526

Orthologous Gene

Mouse[1]  NM_001172092, NM_001172093, NM_029523
Rat[1]  NM_001172092, NM_001172093, NM_029523

Chromosomal Region

1p31.2  [68,939,835  -  68,962,904]

Gene Family (Interpro ID)

IPR000591  DEP domain
IPR008936  Rho GTPase activation protein
IPR000198  RhoGAP
IPR011991  Winged helix repressor DNA-binding

Link to Pubmed  (Pubmed ID)

8125298
12477932
14702039
16344560
17452976
19322201
20379614
20587513
21139048
21906983
23646139

Gene Ontology  (GO ID)

Biological Process

GO:0045892  negative regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005634  nucleus
GO:0017053  transcriptional repressor complex

Molecular Function

GO:0005096  GTPase activator activity
GO:0005515  protein binding