protein kinase C, theta

jump to detail

Synonym

PRKCQ, MGC141919, PRKCT, protein kinase C, theta, Protein kinase C theta type, MGC126514, nPKC-theta

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:23.70

cerebellum:50.40

brain stem:-

corpus callosum/glia:58.30

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:5.90

artery/aorta:-

vein:-

lymphnode:30.30

peripheral blood:18.20

spleen:37.80

thymus:154.60

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:5.82

cerebellum:5.31

brain stem:5.83

corpus callosum/glia:6.03

pineal gland:-

peripheral nerve:5.17

spine:5.74

retina:-

eye:-

artery/aorta:5.45

vein:5.37

lymphnode:6.12

peripheral blood:-

spleen:6.06

thymus:7.38

bone marrow:6.05

adipose:5.67

bone:-

skin:5.63

CAGE

cerebrum:1.74

cerebellum:-

brain stem:1.97

corpus callosum/glia:2.69

pineal gland:0.36

peripheral nerve:-

spine:1.48

retina:-

eye:-

artery/aorta:1.52

vein:2.66

lymphnode:2.72

peripheral blood:-

spleen:1.69

thymus:3.91

bone marrow:-

adipose:1.63

bone:-

skin:-

RNA-seq

cerebrum:1.97

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.26

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.10

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:3.60

prostate:22.50

ovary:37.30

testis:-

heart:38.30

muscle:40.20

esophagus:-

stomach:63.70

intestine:64.80

colon:8.50

liver/hepato:21.10

lung:24.40

bladder:-

kidney:31.20

pituitary:-

thyroid/parathyroid:163.70

adrenal gland:-

pancreas:-

breast:9.30

salivary:-

GeneChip

uterus:5.40

placenta:5.14

prostate:4.99

ovary:5.48

testis:5.17

heart:5.11

muscle:8.04

esophagus:5.87

stomach:5.31

intestine:5.92

colon:5.72

liver/hepato:5.37

lung:5.50

bladder:-

kidney:5.97

pituitary:5.59

thyroid/parathyroid:6.52

adrenal gland:5.26

pancreas:5.75

breast:5.20

salivary:5.10

CAGE

uterus:1.12

placenta:0.24

prostate:0.81

ovary:1.00

testis:0.78

heart:0.25

muscle:3.82

esophagus:1.31

stomach:-

intestine:1.56

colon:0.90

liver/hepato:0.14

lung:1.96

bladder:1.47

kidney:1.67

pituitary:0.10

thyroid/parathyroid:2.63

adrenal gland:-

pancreas:2.48

breast:0.90

salivary:0.83

RNA-seq

uterus:-

placenta:-

prostate:0.22

ovary:0.85

testis:1.35

heart:0.10

muscle:5.35

esophagus:-

stomach:-

intestine:-

colon:0.10

liver/hepato:0.07

lung:1.55

bladder:-

kidney:2.13

pituitary:-

thyroid/parathyroid:3.92

adrenal gland:1.76

pancreas:-

breast:1.09

salivary:-

IDs

Refseq ID	NM_006257
Gene ID	5588
Unigene ID	Hs.498570
Probe set ID	210039_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000065675
GTEx ID	ENSG00000065675

Orthologous Gene

Mouse[1]	NM_008859
Rat[1]	NM_008859

Chromosomal Region

10p14 [6,469,105 - 6,622,263]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000961	AGC-kinase, C-terminal
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0007411	axon guidance
GO:0007596	blood coagulation
GO:0006921	cell structure disassembly during apoptosis
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0006509	membrane protein ectodomain proteolysis
GO:0046627	negative regulation of insulin receptor signaling pathway
GO:0070233	negative regulation of T cell apoptosis
GO:0007603	phototransduction, visible light
GO:0030168	platelet activation
GO:0032740	positive regulation of interleukin-17 production
GO:0045086	positive regulation of interleukin-2 biosynthetic process
GO:0032753	positive regulation of interleukin-4 production
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0050870	positive regulation of T cell activation
GO:0042102	positive regulation of T cell proliferation
GO:0006468	protein amino acid phosphorylation
GO:0016567	protein ubiquitination
GO:0001558	regulation of cell growth
GO:0022400	regulation of rhodopsin mediated signaling pathway
GO:0006355	regulation of transcription, DNA-dependent
GO:0016056	rhodopsin mediated signaling pathway
GO:0050852	T cell receptor signaling pathway

Cellular Component

GO:0005829	cytosol
GO:0001772	immunological synapse
GO:0005622	intracellular
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0042802	identical protein binding
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0004697	protein kinase C activity
GO:0004674	protein serine/threonine kinase activity
GO:0004842	ubiquitin-protein ligase activity

protein kinase C, theta

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function