kelch-like 4 (Drosophila)

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Synonym

KHL4, Kelch-like protein 4, KIAA1687, kelch-like 4 (Drosophila), KLHL4, DKELCHL, kelch (Drosophila)-like 4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:77 cerebellum:50.40 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:- spine:- retina:- eye:11.80 artery/aorta:89.90 vein:- lymphnode:- peripheral blood:- spleen:18.90 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.11 cerebellum:3.49 brain stem:4.02 corpus callosum/glia:4.64 pineal gland:- peripheral nerve:3.24 spine:3.97 retina:- eye:- artery/aorta:3.29 vein:3.55 lymphnode:3.49 peripheral blood:- spleen:3.29 thymus:2.96 bone marrow:3.35 adipose:3.51 bone:- skin:3.32
CAGE cerebrum:2.04 cerebellum:- brain stem:2.60 corpus callosum/glia:2.60 pineal gland:2.69 peripheral nerve:- spine:2.59 retina:- eye:- artery/aorta:0.34 vein:0.96 lymphnode:0.67 peripheral blood:- spleen:0.88 thymus:0.18 bone marrow:- adipose:0.14 bone:- skin:-
RNA-seq cerebrum:0.95 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.46 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.23 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:- prostate:- ovary:- testis:69.20 heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:14.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.44 placenta:3.07 prostate:3.11 ovary:3.77 testis:3.57 heart:3.50 muscle:3.46 esophagus:3.17 stomach:3.41 intestine:3.31 colon:3.35 liver/hepato:3.49 lung:3.09 bladder:- kidney:3.38 pituitary:3.22 thyroid/parathyroid:3.26 adrenal gland:5.54 pancreas:3.46 breast:3.29 salivary:3.20
CAGE uterus:1.44 placenta:0.24 prostate:0.49 ovary:1.92 testis:2.48 heart:0.52 muscle:0.13 esophagus:0.77 stomach:- intestine:0.43 colon:0.61     liver/hepato:0.46    lung:0.28 bladder:0.73 kidney:1.01 pituitary:0.10 thyroid/parathyroid:0.53 adrenal gland:- pancreas:0 breast:0.55 salivary:0
RNA-seq uterus:- placenta:- prostate:0.06 ovary:0.92 testis:0.52 heart:0.04 muscle:0.02 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.01        lung:0.19    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.06 salivary:-

Gene Information

IDs

Refseq ID NM_057162
Gene ID 56062
Unigene ID Hs.49075
Probe set ID 214591_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000102271
GTEx ID ENSG00000102271

Orthologous Gene

Mouse[1]  NM_172781
Rat[1]  NM_001108244

Chromosomal Region

Xq21.31  [86,772,752  -  86,925,050]

Gene Family (Interpro ID)

IPR011333  BTB/POZ fold
IPR000210  BTB/POZ-like

Link to Pubmed  (Pubmed ID)

10888605
11214970
11401425
11499681
12477932
14702039
15772651
16344560
18029348
18039948
21145461
23676014

Gene Ontology  (GO ID)

Biological Process

GO:0008150  biological_process

Cellular Component

GO:0005737  cytoplasm
GO:0043231  intracellular membrane-bounded organelle
GO:0015630  microtubule cytoskeleton
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0003779  actin binding
GO:0003674  molecular_function