homeobox and leucine zipper encoding

 jump to detail

Synonym

Homeodomain leucine zipper-containing factor, Homeobox and leucine zipper protein Homez, KIAA1443, HOMEZ

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:4.70 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:11.80 artery/aorta:- vein:- lymphnode:20.20 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:14.40
GeneChip nodata
CAGE cerebrum:2.28 cerebellum:- brain stem:2.58 corpus callosum/glia:3.10 pineal gland:2.90 peripheral nerve:- spine:2.58 retina:- eye:- artery/aorta:2.30 vein:2.83 lymphnode:2.71 peripheral blood:- spleen:2.69 thymus:3.14 bone marrow:- adipose:2.67 bone:- skin:-
RNA-seq cerebrum:1.02 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.07 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.88 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:14.60 prostate:- ovary:- testis:82.20 heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:21.10        lung:24.40    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip nodata
CAGE uterus:2.70 placenta:2.42 prostate:3.04 ovary:2.95 testis:4.07 heart:2.59 muscle:2.61 esophagus:3.11 stomach:- intestine:2.73 colon:2.63     liver/hepato:2.12    lung:2.71 bladder:3.06 kidney:2.98 pituitary:2.58 thyroid/parathyroid:3.16 adrenal gland:- pancreas:2.86 breast:2.87 salivary:3.37
RNA-seq uterus:- placenta:- prostate:2.11 ovary:2.91 testis:3.31 heart:1.45 muscle:1.97 esophagus:- stomach:- intestine:- colon:1.77     liver/hepato:1.39        lung:1.27    bladder:- kidney:2.52 pituitary:- thyroid/parathyroid:2.14 adrenal gland:1.47 pancreas:- breast:2.13 salivary:-

Gene Information

IDs

Refseq ID NM_020834
Gene ID 57594
Unigene ID Hs.632332
Probe set ID -
Ensembl ID ENSG00000215271
GTEx ID ENSG00000215271

Orthologous Gene

Mouse[1]  NM_001177705, NM_183174
Rat[1]  NM_152849, NM_183174

Chromosomal Region

14q11.2  [23,742,844  -  23,762,787]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

10718198
11948623
12477932
12925734
14702039
15302935
15489334
18029348
19471022
20422016
21890473
23574532
23718855

Gene Ontology  (GO ID)

Biological Process

GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity