pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

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Synonym

PEPP-1, PLEKHA4, Phosphoinositol 3-phosphate-binding protein 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:17.80 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:41.10 artery/aorta:179.90 vein:- lymphnode:10.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.80 skin:19.20
GeneChip cerebrum:5.01 cerebellum:5.05 brain stem:5.11 corpus callosum/glia:5.22 pineal gland:- peripheral nerve:8.65 spine:5.10 retina:- eye:- artery/aorta:6.07 vein:6.13 lymphnode:5.28 peripheral blood:- spleen:5.01 thymus:4.45 bone marrow:4.96 adipose:5.54 bone:- skin:5.59
CAGE cerebrum:0.48 cerebellum:- brain stem:1.28 corpus callosum/glia:0.99 pineal gland:0.62 peripheral nerve:- spine:1.53 retina:- eye:- artery/aorta:2.38 vein:0.47 lymphnode:1.06 peripheral blood:- spleen:1.12 thymus:1.06 bone marrow:- adipose:1.01 bone:- skin:-
RNA-seq cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.95 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.30 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:11.30 ovary:- testis:- heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:9.80    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:53.30 breast:18.60 salivary:-
GeneChip uterus:5.47 placenta:4.96 prostate:4.82 ovary:5.51 testis:4.91 heart:5.86 muscle:5.46 esophagus:5.36 stomach:5.34 intestine:5.44 colon:5.60 liver/hepato:5.24 lung:5.40 bladder:- kidney:5.12 pituitary:5.44 thyroid/parathyroid:5.23 adrenal gland:5.44 pancreas:5.41 breast:5.78 salivary:5.09
CAGE uterus:0.76 placenta:0.81 prostate:1.46 ovary:2.32 testis:0.89 heart:1.46 muscle:0.77 esophagus:1.31 stomach:- intestine:0.84 colon:0.99     liver/hepato:1.07    lung:1.16 bladder:1.45 kidney:1.09 pituitary:1.09 thyroid/parathyroid:1.62 adrenal gland:- pancreas:1.42 breast:0.90 salivary:0
RNA-seq uterus:- placenta:- prostate:0.63 ovary:3.08 testis:1.51 heart:0.94 muscle:0.96 esophagus:- stomach:- intestine:- colon:1.89     liver/hepato:0.12        lung:0.28    bladder:- kidney:0.84 pituitary:- thyroid/parathyroid:1.43 adrenal gland:1.96 pancreas:- breast:1.72 salivary:-

Gene Information

IDs

Refseq ID NM_001161354
Gene ID 57664
Unigene ID Hs.94695
Probe set ID 219011_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000105559
GTEx ID ENSG00000105559

Orthologous Gene

Mouse[3]  NM_148927
Rat [0]  

Chromosomal Region

19q13.33  [49,340,355  -  49,371,884]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

11001876
12477932
15489334
16169070
21988832

Gene Ontology  (GO ID)

Biological Process

GO:0008150  biological_process

Cellular Component

GO:0005575  cellular_component
GO:0005737  cytoplasm
GO:0016020  membrane

Molecular Function

GO:0005545  phosphatidylinositol binding