protein tyrosine phosphatase, receptor type, C

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Synonym

CD45 antigen, L-CA, PTPRC, CD45, LY5, Leukocyte common antigen precursor, protein tyrosine phosphatase, receptor type, C, T200, B220, GP180

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.81 cerebellum:4.65 brain stem:6.26 corpus callosum/glia:7.75 pineal gland:- peripheral nerve:7.16 spine:7.68 retina:- eye:- artery/aorta:6.55 vein:7.74 lymphnode:10.47 peripheral blood:- spleen:11.32 thymus:11.59 bone marrow:10.45 adipose:7.66 bone:- skin:6.79
CAGE cerebrum:2.78 cerebellum:- brain stem:3.61 corpus callosum/glia:3.10 pineal gland:2.70 peripheral nerve:- spine:4.35 retina:- eye:- artery/aorta:3.47 vein:5.78 lymphnode:6.14 peripheral blood:- spleen:6.37 thymus:6.87 bone marrow:- adipose:4.22 bone:- skin:-
RNA-seq cerebrum:2.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.90 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.67 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.10 placenta:7.16 prostate:6.32 ovary:7.28 testis:4.70 heart:6.56 muscle:4.78 esophagus:6.87 stomach:8.61 intestine:7.45 colon:7.69 liver/hepato:8.17 lung:10.36 bladder:- kidney:5.31 pituitary:4.61 thyroid/parathyroid:6.95 adrenal gland:6.14 pancreas:6.57 breast:7.55 salivary:5.96
CAGE uterus:3.20 placenta:3.42 prostate:3.49 ovary:3.11 testis:2.72 heart:2.97 muscle:1.97 esophagus:3.56 stomach:- intestine:4.16 colon:3.39     liver/hepato:3.46    lung:5.40 bladder:4.43 kidney:3.30 pituitary:2.45 thyroid/parathyroid:2.59 adrenal gland:- pancreas:1.98 breast:2.53 salivary:3.56
RNA-seq uterus:- placenta:- prostate:2.06 ovary:2.10 testis:1.81 heart:1.57 muscle:0.41 esophagus:- stomach:- intestine:- colon:1.57     liver/hepato:1.76        lung:5.38    bladder:- kidney:1.99 pituitary:- thyroid/parathyroid:1.43 adrenal gland:5.32 pancreas:- breast:2.31 salivary:-

IDs

Refseq ID NM_080921
Gene ID 5788
Unigene ID -
Probe set ID 212587_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000081237
GTEx ID ENSG00000081237

Orthologous Gene

Mouse[2]  NM_001111316, NM_011210
Rat[16]  NM_001109887, NM_001109888, NM_001109889, NM_001109890, NM_138507

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

1355979
1373652
1648262
1655467
1680916
1695146
1793833
1834739
1970422
1976695
2169617
2524382
2531281
2550143
2824653
2845400
2853967
2956090
2971730
7516335
7526385
7537381
7539755
7737297
7961877
8157290
8473339
8537410
8557683
8570203
8576115
8663450
8703037
8955171
8980254
9148925
9197241
9368621
9403695
9535845
9573028
9624153
9973453
10066810
10228003
10229804
10330160
10358156
10369126
10415030
10473580
10490978
10683443
10700239
10702677
10921916
11101853
11145714
11201744
11254687
11369760
11528386
11548742
11551930
11564800
11778694
11804554
11827988
11841494
11862398
11877294
11909961
11975983
11994288
12008046
12022705
12028593
12073144
12100025
12147336
12354383
12376545
12386161
12393728
12430875
12477932
12499376
12519755
12519789
12556471
12560083
12574355
12589038
12589045
12595907
12618866
12626536
12633939
12716971
12820694
12864992
12880639
14525771
14565647
14625311
14631169
14636588
14641523
14684825
14726805
14979481
14983037
15014144
15018649
15057492
15085197
15214936
15231748
15240561
15275963
15302935
15314282
15333587
15548260
15584483
15603882
15624328
15626731
15684325
15687496
15808544
15946252
15960938
15963758
16172127
16247487
16269626
16332974
16341674
16344560
16360841
16378074
16393978
16503409
16505159
16524887
16538473
16857986
16955142
16998493
16999868
17122895
17172930
17213291
17242371
17378731
17524482
17591854
17635802
17656643
17692374
17803443
17823079
17897956
18029348
18157742
18174230
18292296
18312479
18511809
18634151
18669861
18680516
18719244
18840711
18992193
19059880
19111528
19167335
19246294
19332764
19454697
19481264
19546439
19585516
19635795
19850743
19879912
19898481
19946888
20093141
20119835
20139978
20156100
20164196
20191119
20231690
20309874
20505149
20932480
21054833
21067564
21106704
21179414
21278234
21507955
21599592
21768350
21818290
21890473
21952639
21952740
22171268
22174689
22268729
22386990
22438252
22458809
22505724
22524693
22606231
22689986
22783574
22821963
22937208
23065155
23171577
23206327
23394998
23396948
23733486
23747721
23840798
23911702
23997015
24211716
24211831
24231767
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0042100  B cell proliferation
GO:0050853  B cell receptor signaling pathway
GO:0048539  bone marrow development
GO:0007166  cell surface receptor linked signal transduction
GO:0051607  defense response to virus
GO:0016311  dephosphorylation
GO:0002244  hemopoietic progenitor cell differentiation
GO:0002378  immunoglobulin biosynthetic process
GO:0006933  negative regulation of cell adhesion involved in substrate-bound cell migration
GO:0001960  negative regulation of cytokine-mediated signaling pathway
GO:0006469  negative regulation of protein kinase activity
GO:0001915  negative regulation of T cell mediated cytotoxicity
GO:0050857  positive regulation of antigen receptor-mediated signaling pathway
GO:0030890  positive regulation of B cell proliferation
GO:0045860  positive regulation of protein kinase activity
GO:0042102  positive regulation of T cell proliferation
GO:0006470  protein amino acid dephosphorylation
GO:0051726  regulation of cell cycle
GO:0033261  regulation of S phase
GO:0051209  release of sequestered calcium ion into cytosol
GO:0048864  stem cell development
GO:0030217  T cell differentiation
GO:0050852  T cell receptor signaling pathway

Cellular Component

GO:0009897  external side of plasma membrane
GO:0005925  focal adhesion
GO:0005887  integral to plasma membrane
GO:0045121  membrane raft
GO:0005886  plasma membrane

Molecular Function

GO:0005515  protein binding
GO:0019901  protein kinase binding
GO:0004725  protein tyrosine phosphatase activity
GO:0005001  transmembrane receptor protein tyrosine phosphatase activity