protein tyrosine phosphatase, receptor type, F

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Synonym

LAR, Leukocyte antigen related, FLJ45567, PTPRF, FLJ43335, FLJ45062, protein tyrosine phosphatase, receptor type, F, LAR protein

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:115 cerebellum:63 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:153.40 spine:561.50 retina:- eye:158.70 artery/aorta:30 vein:866.40 lymphnode:- peripheral blood:- spleen:37.80 thymus:77.30 bone marrow:39.40 adipose:201.70 bone:76.80 skin:144
GeneChip cerebrum:8.39 cerebellum:7 brain stem:8.16 corpus callosum/glia:8.68 pineal gland:- peripheral nerve:8.61 spine:8.41 retina:- eye:- artery/aorta:8.28 vein:7.36 lymphnode:7.70 peripheral blood:- spleen:6.29 thymus:8.14 bone marrow:6.23 adipose:9.61 bone:- skin:9.53
CAGE cerebrum:3.52 cerebellum:- brain stem:3.57 corpus callosum/glia:3.80 pineal gland:3.03 peripheral nerve:- spine:3.55 retina:- eye:- artery/aorta:3.28 vein:3.25 lymphnode:3.20 peripheral blood:- spleen:1.32 thymus:2.44 bone marrow:- adipose:3.81 bone:- skin:-
RNA-seq cerebrum:0.88 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.52 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.11 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:136.70 placenta:313.30 prostate:157.70 ovary:- testis:51.90 heart:102.20 muscle:- esophagus:- stomach:233.70 intestine:64.80 colon:339.20     liver/hepato:31.70        lung:185.70    bladder:125.60 kidney:93.60 pituitary:116 thyroid/parathyroid:- adrenal gland:- pancreas:124.50 breast:232.30 salivary:-
GeneChip uterus:8.34 placenta:10.01 prostate:10 ovary:9.02 testis:7.09 heart:6.78 muscle:5.52 esophagus:9.50 stomach:8.50 intestine:8.31 colon:9.21 liver/hepato:9.30 lung:8.15 bladder:- kidney:8.70 pituitary:8.39 thyroid/parathyroid:8.87 adrenal gland:6.97 pancreas:8.06 breast:9.98 salivary:10.27
CAGE uterus:3.40 placenta:5.11 prostate:3.85 ovary:3.33 testis:2.46 heart:2.49 muscle:1.76 esophagus:4.16 stomach:- intestine:4.80 colon:4.60     liver/hepato:4.55    lung:3.60 bladder:3.39 kidney:3.23 pituitary:2.82 thyroid/parathyroid:3.43 adrenal gland:- pancreas:4.07 breast:4.41 salivary:4.71
RNA-seq uterus:- placenta:- prostate:1.40 ovary:0.37 testis:0.00 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.78        lung:1.82    bladder:- kidney:0.17 pituitary:- thyroid/parathyroid:0.86 adrenal gland:0.00 pancreas:- breast:0.32 salivary:-

Gene Information

IDs

Refseq ID NM_002840
Gene ID 5792
Unigene ID Hs.272062
Probe set ID 200636_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000142949
GTEx ID ENSG00000142949

Orthologous Gene

Mouse[3]  NM_011213
Rat [0]  

Chromosomal Region

1p34.2  [43,990,858  -  44,089,343]

Gene Family (Interpro ID)

IPR003961  Fibronectin, type III
IPR008957  Fibronectin, type III-like fold
IPR000242  Protein-tyrosine phosphatase, receptor/non-receptor type

Link to Pubmed  (Pubmed ID)

1321126
1486801
1695146
2554325
2972792
7558042
7665159
7796809
7929208
8524829
8621380
8643598
8732688
8917069
8995282
9245795
9295285
9624153
9647658
10079136
10187801
10320483
10338209
10365916
10395287
10660596
10777529
10822386
11121408
11158333
11245482
11309481
11931740
12095414
12176037
12376545
12477932
12496362
12629171
14702039
15150650
15231748
15491607
15588985
15896785
16335952
16478662
17259169
17419996
17803936
18925540
19199708
19910497
20139422
21139048
21697133
21875946
21890473
21906983
21963094
22959728
23000965
23986473
24797263

Gene Ontology  (GO ID)

Biological Process

GO:0007155  cell adhesion
GO:0007185  transmembrane receptor protein tyrosine phosphatase signaling pathway

Cellular Component

GO:0005887  integral to plasma membrane

Molecular Function

GO:0008201  heparin binding
GO:0004725  protein tyrosine phosphatase activity
GO:0005001  transmembrane receptor protein tyrosine phosphatase activity