RAB27A, member RAS oncogene family

Synonym

GS2, Rab-27, Ras-related protein Rab-27A, MGC117246, GTP-binding protein Ram, RAB27A, member RAS oncogene family, RAB27A, RAB27, RAM, HsT18676

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:5.35

cerebellum:5.35

brain stem:5.56

corpus callosum/glia:5.43

pineal gland:-

peripheral nerve:5.97

spine:5.79

retina:-

eye:-

artery/aorta:6.95

vein:6.81

lymphnode:7.85

peripheral blood:-

spleen:8.38

thymus:7.03

bone marrow:9.11

adipose:6.69

bone:-

skin:6.83

CAGE

cerebrum:1.18

cerebellum:-

brain stem:1.77

corpus callosum/glia:1.04

pineal gland:1.37

peripheral nerve:-

spine:2.14

retina:-

eye:-

artery/aorta:3.13

vein:2.71

lymphnode:3.08

peripheral blood:-

spleen:3.11

thymus:2.24

bone marrow:-

adipose:2.34

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.11

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:7.09

placenta:6.23

prostate:9.66

ovary:6.89

testis:6.33

heart:6.33

muscle:5.15

esophagus:6.79

stomach:8.54

intestine:7.04

colon:7.22

liver/hepato:8.26

lung:8.45

bladder:-

kidney:6.22

pituitary:9.47

thyroid/parathyroid:7.64

adrenal gland:7.70

pancreas:7.50

breast:6.99

salivary:6.07

CAGE

uterus:2.20

placenta:1.99

prostate:3.02

ovary:2.38

testis:2.05

heart:2.34

muscle:1.48

esophagus:2.65

stomach:-

intestine:2.79

colon:2.63

liver/hepato:3.83

lung:3.54

bladder:2.85

kidney:2.55

pituitary:4.16

thyroid/parathyroid:3.11

adrenal gland:-

pancreas:2.98

breast:3.02

salivary:1.58

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.15

testis:0.00

heart:0.00

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.46

lung:0.00

bladder:-

kidney:0.18

pituitary:-

thyroid/parathyroid:0.29

adrenal gland:0.00

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_183234
Gene ID	5873
Unigene ID	-
Probe set ID	209515_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000069974
GTEx ID	ENSG00000069974

Orthologous Gene

Mouse[2]	NM_023635
Rat [0]

Chromosomal Region

15q21.3 [55,495,164 - 55,582,001]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

LRG_96 [5,001 - 91,210]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002041	Ran GTPase
IPR013753	Ras
IPR001806	Ras GTPase
IPR020849	Ras small GTPase
IPR003579	Ras small GTPase, Rab type
IPR005225	Small GTP-binding protein
IPR020851	Small GTPase
IPR003578	Small GTPase, Rho type

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0007596	blood coagulation
GO:0044267	cellular protein metabolic process
GO:0043316	cytotoxic T cell degranulation
GO:0006887	exocytosis
GO:0030318	melanocyte differentiation
GO:0032402	melanosome transport
GO:0043320	natural killer cell degranulation
GO:0045921	positive regulation of exocytosis
GO:0006605	protein targeting
GO:0007264	small GTPase mediated signal transduction

Cellular Component

GO:0016324	apical plasma membrane
GO:0030425	dendrite
GO:0070382	exocytic vesicle
GO:0005794	Golgi apparatus
GO:0005770	late endosome
GO:0005764	lysosome
GO:0042470	melanosome
GO:0032585	multivesicular body membrane
GO:0001750	photoreceptor outer segment
GO:0030667	secretory granule membrane

Molecular Function

GO:0019003	GDP binding
GO:0005525	GTP binding
GO:0003924	GTPase activity
GO:0031489	myosin V binding
GO:0005515	protein binding
GO:0019904	protein domain specific binding

RAB27A, member RAS oncogene family

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function