arachidonate lipoxygenase 3

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Synonym

MGC119694, MGC119696, e-LOX-3, arachidonate lipoxygenase 3, MGC119695, Epidermis-type lipoxygenase 3, ALOXE3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:3.80 cerebellum:3.96 brain stem:3.79 corpus callosum/glia:3.70 pineal gland:- peripheral nerve:3.69 spine:3.78 retina:- eye:- artery/aorta:3.65 vein:3.95 lymphnode:3.59 peripheral blood:- spleen:3.55 thymus:3.48 bone marrow:3.99 adipose:3.76 bone:- skin:5.66
CAGE cerebrum:0.01 cerebellum:- brain stem:0.03 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:3.50 placenta:4.09 prostate:3.44 ovary:3.53 testis:3.71 heart:3.87 muscle:3.84 esophagus:3.76 stomach:3.90 intestine:3.85 colon:3.90 liver/hepato:3.86 lung:3.48 bladder:- kidney:3.67 pituitary:3.78 thyroid/parathyroid:3.52 adrenal gland:3.59 pancreas:4.38 breast:4.41 salivary:4.13
CAGE uterus:0.04 placenta:0 prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:0.00 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_001165960
Gene ID 59344
Unigene ID -
Probe set ID 222383_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000179148
GTEx ID ENSG00000179148

Orthologous Gene

Mouse[1]  NM_011786
Rat [0]  

Chromosomal Region

17p13.1  [7,999,218  -  8,022,234]

Gene Family (Interpro ID)

IPR008976  Lipase/lipooxygenase, PLAT/LH2
IPR000907  Lipoxygenase
IPR001024  Lipoxygenase, LH2
IPR001885  Lipoxygenase, mammalian

Link to Pubmed  (Pubmed ID)

11350124
11773004
12477932
12881489
14702039
15489334
15629692
16344560
17045234
17139268
17436029
19064572
19131948
19423540
19890349
20301593
20406964
20438785
20921226
20923767
21139048
21963094
22622417
23000965
23954555
24021977

Gene Ontology  (GO ID)

Biological Process

GO:0019369  arachidonic acid metabolic process
GO:0046513  ceramide biosynthetic process
GO:0045444  fat cell differentiation
GO:0051122  hepoxilin biosynthetic process
GO:0019370  leukotriene biosynthetic process
GO:0043651  linoleic acid metabolic process
GO:0019372  lipoxygenase pathway
GO:0019233  sensory perception of pain
GO:0006665  sphingolipid metabolic process

Molecular Function

GO:0051120  hepoxilin A3 synthase activity
GO:0005506  iron ion binding
GO:0016702  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen