RE1-silencing transcription factor

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Synonym

NRSF, XBR, RE1-silencing transcription factor, REST

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:4.70

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:11.80

artery/aorta:60

vein:-

lymphnode:60.70

peripheral blood:-

spleen:-

thymus:25.80

bone marrow:19.70

adipose:-

bone:12.80

skin:28.80

GeneChip

cerebrum:6.90

cerebellum:7.23

brain stem:6.80

corpus callosum/glia:7.14

pineal gland:-

peripheral nerve:7.11

spine:6.80

retina:-

eye:-

artery/aorta:7.03

vein:7.36

lymphnode:7.07

peripheral blood:-

spleen:7.18

thymus:6.48

bone marrow:7.30

adipose:7.10

bone:-

skin:6.71

CAGE

cerebrum:2.81

cerebellum:-

brain stem:2.92

corpus callosum/glia:2.93

pineal gland:3.12

peripheral nerve:-

spine:3.96

retina:-

eye:-

artery/aorta:3.97

vein:4.18

lymphnode:4.13

peripheral blood:-

spleen:4.00

thymus:4.65

bone marrow:-

adipose:3.80

bone:-

skin:-

RNA-seq

cerebrum:0.05

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.18

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.52

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:10.90

prostate:11.30

ovary:-

testis:26

heart:25.50

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:52.80

lung:9.80

bladder:-

kidney:31.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:37.20

salivary:-

GeneChip

uterus:6.89

placenta:7.18

prostate:6.43

ovary:7.15

testis:6.62

heart:7.12

muscle:7.12

esophagus:6.89

stomach:7.08

intestine:7.12

colon:7.21

liver/hepato:7.12

lung:7.30

bladder:-

kidney:7.02

pituitary:6.60

thyroid/parathyroid:6.81

adrenal gland:6.70

pancreas:7.60

breast:6.95

salivary:6.84

CAGE

uterus:3.58

placenta:3.67

prostate:3.99

ovary:3.70

testis:3.83

heart:4.07

muscle:3.68

esophagus:3.76

stomach:-

intestine:3.57

colon:3.59

liver/hepato:3.43

lung:4.06

bladder:3.85

kidney:3.70

pituitary:2.22

thyroid/parathyroid:3.63

adrenal gland:-

pancreas:3.77

breast:4.81

salivary:2.78

RNA-seq

uterus:-

placenta:-

prostate:0.47

ovary:0.33

testis:0.91

heart:1.09

muscle:0.81

esophagus:-

stomach:-

intestine:-

colon:0.26

liver/hepato:0.16

lung:0.39

bladder:-

kidney:0.05

pituitary:-

thyroid/parathyroid:0.67

adrenal gland:0.14

pancreas:-

breast:0.58

salivary:-

IDs

Refseq ID	NM_005612
Gene ID	5978
Unigene ID	Hs.631513
Probe set ID	204535_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000084093
GTEx ID	ENSG00000084093

Orthologous Gene

Mouse[2]	NM_011263
Rat [0]

Chromosomal Region

4q12 [57,774,042 - 57,813,577]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR015880	Zinc finger, C2H2-like
IPR007087	Zinc finger, C2H2-type

Gene Ontology (GO ID)

Biological Process

GO:0060379	cardiac muscle cell myoblast differentiation
GO:0071257	cellular response to electrical stimulus
GO:0071385	cellular response to glucocorticoid stimulus
GO:0070933	histone H4 deacetylation
GO:0043922	negative regulation by host of viral transcription
GO:0032348	negative regulation of aldosterone biosynthetic process
GO:0045955	negative regulation of calcium ion-dependent exocytosis
GO:0008285	negative regulation of cell proliferation
GO:0010629	negative regulation of gene expression
GO:0046676	negative regulation of insulin secretion
GO:0050768	negative regulation of neurogenesis
GO:0045665	negative regulation of neuron differentiation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0043065	positive regulation of apoptosis
GO:0043280	positive regulation of caspase activity
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006355	regulation of transcription, DNA-dependent

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0017053	transcriptional repressor complex

Molecular Function

GO:0003682	chromatin binding
GO:0044212	DNA regulatory region binding
GO:0046872	metal ion binding
GO:0015271	outward rectifier potassium channel activity
GO:0005515	protein binding
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding

RE1-silencing transcription factor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function