sortilin 1

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Synonym

100 kDa NT receptor, Sortilin precursor, SORT1, Gp95, sortilin 1, Glycoprotein 95, NTR3, Neurotensin receptor 3

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:215.70

cerebellum:113.30

brain stem:-

corpus callosum/glia:87.50

pineal gland:-

peripheral nerve:153.40

spine:112.30

retina:118.60

eye:123.40

artery/aorta:-

vein:66.60

lymphnode:-

peripheral blood:18.20

spleen:56.70

thymus:25.80

bone marrow:137.80

adipose:80.70

bone:51.20

skin:129.60

GeneChip

cerebrum:6.68

cerebellum:5.45

brain stem:6.84

corpus callosum/glia:7.49

pineal gland:-

peripheral nerve:6.13

spine:7.22

retina:-

eye:-

artery/aorta:6.76

vein:6.29

lymphnode:5.52

peripheral blood:-

spleen:5.24

thymus:5.38

bone marrow:6.31

adipose:6.63

bone:-

skin:5.95

CAGE

cerebrum:5.11

cerebellum:-

brain stem:5.57

corpus callosum/glia:5.85

pineal gland:3.70

peripheral nerve:-

spine:5.66

retina:-

eye:-

artery/aorta:5.27

vein:3.61

lymphnode:3.51

peripheral blood:-

spleen:3.23

thymus:2.43

bone marrow:-

adipose:4.49

bone:-

skin:-

RNA-seq

cerebrum:6.05

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.38

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.50

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:118.50

placenta:65.60

prostate:45.10

ovary:37.30

testis:134.10

heart:140.50

muscle:40.20

esophagus:-

stomach:-

intestine:-

colon:118.70

liver/hepato:21.10

lung:161.30

bladder:-

kidney:135.20

pituitary:116

thyroid/parathyroid:327.50

adrenal gland:101.60

pancreas:44.50

breast:148.70

salivary:-

GeneChip

uterus:5.69

placenta:6.93

prostate:5.72

ovary:5.43

testis:7.50

heart:6.33

muscle:6.92

esophagus:6.99

stomach:5.53

intestine:6.06

colon:5.64

liver/hepato:5.24

lung:6.46

bladder:-

kidney:5.80

pituitary:5.56

thyroid/parathyroid:6.21

adrenal gland:5.17

pancreas:5.96

breast:5.91

salivary:6.28

CAGE

uterus:3.60

placenta:4.05

prostate:3.57

ovary:2.98

testis:4.75

heart:4.38

muscle:4.57

esophagus:4.14

stomach:-

intestine:4.00

colon:4.06

liver/hepato:2.91

lung:4.64

bladder:3.63

kidney:4.40

pituitary:3.38

thyroid/parathyroid:4.22

adrenal gland:-

pancreas:3.47

breast:4.72

salivary:4.35

RNA-seq

uterus:-

placenta:-

prostate:3.55

ovary:1.89

testis:5.04

heart:4.45

muscle:5.14

esophagus:-

stomach:-

intestine:-

colon:3.39

liver/hepato:2.63

lung:4.23

bladder:-

kidney:5.04

pituitary:-

thyroid/parathyroid:5.11

adrenal gland:2.67

pancreas:-

breast:4.83

salivary:-

IDs

Refseq ID	NM_002959
Gene ID	6272
Unigene ID	Hs.485195
Probe set ID	212807_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000134243
GTEx ID	ENSG00000134243

Orthologous Gene

Mouse[3]	NM_019972
Rat[2]	NM_031767

Chromosomal Region

1p13.3 [109,852,192 - 109,940,573]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0006897	endocytosis
GO:0008333	endosome to lysosome transport
GO:0032509	endosome transport via multivesicular body sorting pathway
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0046323	glucose import
GO:0006895	Golgi to endosome transport
GO:0008625	induction of apoptosis via death domain receptors
GO:0014902	myotube differentiation
GO:0051005	negative regulation of lipoprotein lipase activity
GO:0048011	nerve growth factor receptor signaling pathway
GO:0007218	neuropeptide signaling pathway
GO:0001503	ossification
GO:0048227	plasma membrane to endosome transport
GO:0010468	regulation of gene expression
GO:0032868	response to insulin stimulus
GO:0016050	vesicle organization

Cellular Component

GO:0043025	cell soma
GO:0009986	cell surface
GO:0030136	clathrin-coated vesicle
GO:0005905	coated pit
GO:0005737	cytoplasm
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0030425	dendrite
GO:0005769	early endosome
GO:0005789	endoplasmic reticulum membrane
GO:0005768	endosome
GO:0010008	endosome membrane
GO:0005794	Golgi apparatus
GO:0032580	Golgi cisterna membrane
GO:0016021	integral to membrane
GO:0005765	lysosomal membrane
GO:0031965	nuclear membrane
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane
GO:0030140	trans-Golgi network transport vesicle

Molecular Function

GO:0019899	enzyme binding
GO:0048406	nerve growth factor binding
GO:0010465	nerve growth factor receptor activity
GO:0030379	neurotensin receptor activity, non-G-protein coupled

sortilin 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function