chemokine (C-C motif) ligand 15

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Synonym

NCC3, CCL15, HCC-2, MIP-1 delta, NCC-3, Macrophage inflammatory protein 5, LKN1, LKN-1, MIP-1d, Leukotactin-1, HMRP-2B, Small inducible cytokine A15 precursor, SCYL3, MIP-5, Mrp-2b, SY15, MIP5, chemokine (C-C motif) ligand 15, SCYA15, Lkn-1, Chemokine CC-2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.74 cerebellum:5.42 brain stem:5.92 corpus callosum/glia:5.38 pineal gland:- peripheral nerve:7.42 spine:5.68 retina:- eye:- artery/aorta:8.50 vein:8.74 lymphnode:8.25 peripheral blood:- spleen:10.57 thymus:6.75 bone marrow:7.72 adipose:9.41 bone:- skin:8.21
CAGE cerebrum:0.03 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.69 vein:0 lymphnode:0.20 peripheral blood:- spleen:0.09 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.36 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.85 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:8 placenta:4.91 prostate:7.35 ovary:7.54 testis:6.12 heart:7.62 muscle:6.61 esophagus:7.45 stomach:7.55 intestine:7.16 colon:7.58 liver/hepato:9.10 lung:7.61 bladder:- kidney:6.66 pituitary:7.01 thyroid/parathyroid:7.29 adrenal gland:8.27 pancreas:7.53 breast:8.74 salivary:6.68
CAGE uterus:0.07 placenta:0 prostate:0.66 ovary:0.20 testis:0.04 heart:0.14 muscle:0 esophagus:0.09 stomach:- intestine:3.54 colon:2.91     liver/hepato:2.15    lung:0.98 bladder:0.33 kidney:1.53 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0.55 salivary:0
RNA-seq uterus:- placenta:- prostate:2.17 ovary:0.31 testis:0.26 heart:0.00 muscle:0 esophagus:- stomach:- intestine:- colon:1.48     liver/hepato:3.10        lung:1.57    bladder:- kidney:2.18 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.08 pancreas:- breast:0.26 salivary:-

Gene Information

IDs

Refseq ID NM_032965
Gene ID 6359
Unigene ID -
Probe set ID 205392_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000161574
GTEx ID ENSG00000161574

Orthologous Gene

Mouse[4]  NM_009139, NM_011338
Rat[2]  NM_001012357, NM_001004202

Chromosomal Region

17q12  [34,310,692  -  34,328,590]

Gene Family (Interpro ID)

IPR001811  Small chemokine, interleukin-8-like

Link to Pubmed  (Pubmed ID)

8661057
9129202
9346309
9548457
9558365
9600961
9624581
10202040
10213461
10320325
10604595
11527984
11832479
11888507
11943214
12477932
12759139
14984572
15001559
15179048
15251437
15340161
15894113
15905581
16034099
16341674
16364464
16737685
17296613
17703412
18587271
19203252
19220835
19258923
19669929
19812544
20016943
20126378
20237496
20379614
20503287
20616008
22092970
22147696
22279551
23383108
23690481

Gene Ontology  (GO ID)

Biological Process

GO:0007267  cell-cell signaling
GO:0006874  cellular calcium ion homeostasis
GO:0006935  chemotaxis
GO:0006955  immune response
GO:0050918  positive chemotaxis
GO:0007165  signal transduction

Cellular Component

GO:0005615  extracellular space

Molecular Function

GO:0042056  chemoattractant activity
GO:0008009  chemokine activity
GO:0008201  heparin binding
GO:0005102  receptor binding