serum/glucocorticoid regulated kinase 1

Synonym

SGK, serum/glucocorticoid regulated kinase, SGK1, Serine/threonine-protein kinase Sgk1, Serum/glucocorticoid-regulated kinase 1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:280.90

cerebellum:302.30

brain stem:-

corpus callosum/glia:1399.70

pineal gland:-

peripheral nerve:122.70

spine:224.60

retina:118.60

eye:205.70

artery/aorta:2667.80

vein:266.60

lymphnode:30.30

peripheral blood:619.40

spleen:208

thymus:296.30

bone marrow:19.70

adipose:282.30

bone:447.80

skin:451.20

GeneChip

cerebrum:8.53

cerebellum:7.75

brain stem:8.56

corpus callosum/glia:9.89

pineal gland:-

peripheral nerve:8.71

spine:9.18

retina:-

eye:-

artery/aorta:7.90

vein:8.24

lymphnode:8.64

peripheral blood:-

spleen:7.98

thymus:7.87

bone marrow:7.21

adipose:8.34

bone:-

skin:9.30

CAGE

cerebrum:5.04

cerebellum:-

brain stem:5.54

corpus callosum/glia:5.97

pineal gland:5.84

peripheral nerve:-

spine:5.71

retina:-

eye:-

artery/aorta:4.46

vein:3.99

lymphnode:4.51

peripheral blood:-

spleen:4.03

thymus:3.75

bone marrow:-

adipose:4.97

bone:-

skin:-

RNA-seq

cerebrum:0.94

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.66

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.06

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:464.80

placenta:200.40

prostate:191.50

ovary:298.10

testis:151.40

heart:89.40

muscle:-

esophagus:-

stomach:148.70

intestine:162

colon:152.60

liver/hepato:84.40

lung:337.20

bladder:1004.90

kidney:353.50

pituitary:-

thyroid/parathyroid:-

adrenal gland:1218.90

pancreas:35.60

breast:83.60

salivary:-

GeneChip

uterus:8.67

placenta:9.19

prostate:8.55

ovary:9.48

testis:8.72

heart:8.27

muscle:8.58

esophagus:8.96

stomach:8.17

intestine:8.89

colon:8.49

liver/hepato:8.19

lung:9.69

bladder:-

kidney:9.04

pituitary:6.22

thyroid/parathyroid:9.21

adrenal gland:10.32

pancreas:8.87

breast:8.70

salivary:7.96

CAGE

uterus:4.74

placenta:4.82

prostate:3.90

ovary:5.81

testis:4.64

heart:3.99

muscle:3.78

esophagus:5.04

stomach:-

intestine:6.85

colon:5.20

liver/hepato:5.75

lung:4.86

bladder:4.36

kidney:5.59

pituitary:3.89

thyroid/parathyroid:4.79

adrenal gland:-

pancreas:5.31

breast:4.40

salivary:4.44

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:1.96

testis:0.00

heart:0.17

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:2.23

lung:0.28

bladder:-

kidney:1.38

pituitary:-

thyroid/parathyroid:0.17

adrenal gland:1.69

pancreas:-

breast:0.20

salivary:-

IDs

Refseq ID	NM_001143677
Gene ID	6446
Unigene ID	Hs.510078
Probe set ID	201739_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000118515
GTEx ID	ENSG00000118515

Orthologous Gene

Mouse[6]	NM_001161845, NM_001161847, NM_001161848, NM_001161849, NM_001161850, NM_011361
Rat [0]

Chromosomal Region

6q23.2 [134,490,384 - 134,639,250]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000961	AGC-kinase, C-terminal
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0034220	ion transmembrane transport
GO:0007616	long-term memory
GO:0032411	positive regulation of transporter activity
GO:0006468	protein amino acid phosphorylation
GO:0042981	regulation of apoptosis
GO:0008217	regulation of blood pressure
GO:0050790	regulation of catalytic activity
GO:0001558	regulation of cell growth
GO:0030334	regulation of cell migration
GO:0042127	regulation of cell proliferation
GO:0060453	regulation of gastric acid secretion
GO:0051090	regulation of transcription factor activity
GO:0070294	renal sodium ion absorption
GO:0006974	response to DNA damage stimulus
GO:0006950	response to stress
GO:0006814	sodium ion transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005829	cytosol
GO:0005789	endoplasmic reticulum membrane
GO:0005739	mitochondrion
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0005246	calcium channel regulator activity
GO:0017081	chloride channel regulator activity
GO:0015459	potassium channel regulator activity
GO:0004674	protein serine/threonine kinase activity
GO:0017080	sodium channel regulator activity

serum/glucocorticoid regulated kinase 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function