WNK lysine deficient protein kinase 1

Synonym

Protein kinase, lysine-deficient 1, KDP, PHA2C, PRKWNK1, WNK lysine deficient protein kinase 1, WNK1, Serine/threonine-protein kinase WNK1, Protein kinase with no lysine 1, Kinase deficient protein, KIAA0344

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:6.97

cerebellum:5.68

brain stem:6.94

corpus callosum/glia:7.62

pineal gland:-

peripheral nerve:6.35

spine:7.15

retina:-

eye:-

artery/aorta:6.18

vein:6.48

lymphnode:6.65

peripheral blood:-

spleen:7.23

thymus:5.78

bone marrow:7.25

adipose:6.11

bone:-

skin:5.98

CAGE

cerebrum:5.02

cerebellum:-

brain stem:5.21

corpus callosum/glia:5.38

pineal gland:4.52

peripheral nerve:-

spine:5.74

retina:-

eye:-

artery/aorta:4.99

vein:4.77

lymphnode:4.62

peripheral blood:-

spleen:4.45

thymus:4.61

bone marrow:-

adipose:4.61

bone:-

skin:-

RNA-seq

cerebrum:2.14

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.70

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.59

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:5.74

placenta:5.73

prostate:5.79

ovary:6.06

testis:6.28

heart:7.26

muscle:6.47

esophagus:6.59

stomach:6.72

intestine:5.23

colon:5.69

liver/hepato:7.14

lung:6.90

bladder:-

kidney:7.24

pituitary:5.47

thyroid/parathyroid:6.26

adrenal gland:6.90

pancreas:4.53

breast:6.65

salivary:5.58

CAGE

uterus:4.32

placenta:3.84

prostate:4.09

ovary:4.14

testis:4.63

heart:5.06

muscle:4.66

esophagus:4.58

stomach:-

intestine:3.75

colon:4.15

liver/hepato:4.12

lung:4.92

bladder:4.54

kidney:5.11

pituitary:4.26

thyroid/parathyroid:3.72

adrenal gland:-

pancreas:3.93

breast:5.46

salivary:3.35

RNA-seq

uterus:-

placenta:-

prostate:1.95

ovary:1.33

testis:3.33

heart:5.00

muscle:3.31

esophagus:-

stomach:-

intestine:-

colon:1.34

liver/hepato:0.79

lung:1.96

bladder:-

kidney:2.47

pituitary:-

thyroid/parathyroid:2.54

adrenal gland:1.19

pancreas:-

breast:1.52

salivary:-

IDs

Refseq ID	NM_018979
Gene ID	65125
Unigene ID	-
Probe set ID	211993_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000060237
GTEx ID	ENSG00000060237

Orthologous Gene

Mouse[2]	NM_001185020, NM_001185021, NM_198703
Rat[1]	NM_053794, NM_001185021, NM_198703

Chromosomal Region

12p13.33 [861,759 - 1,020,618]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

GO:0006811	ion transport
GO:0090188	negative regulation of pancreatic juice secretion
GO:0010923	negative regulation of phosphatase activity
GO:0048666	neuron development
GO:0003084	positive regulation of systemic arterial blood pressure
GO:0006468	protein amino acid phosphorylation
GO:0007243	protein kinase cascade
GO:0050794	regulation of cellular process

GO:0005524	ATP binding
GO:0019902	phosphatase binding
GO:0005515	protein binding
GO:0004860	protein kinase inhibitor activity
GO:0004674	protein serine/threonine kinase activity

WNK lysine deficient protein kinase 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function