secretory leukocyte peptidase inhibitor

Synonym

Protease inhibitor WAP4, WFDC4, WAP4, WAP four-disulfide core domain protein 4, MPI, HUSI-1, secretory leukocyte peptidase inhibitor, SLPI, ALK1, Seminal proteinase inhibitor, BLPI, Secretory leukocyte protease inhibitor, HUSI-I, Mucus proteinase inhibitor, Antileukoproteinase 1 precursor, HUSI

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:10.70

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:111.70

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:98.40

adipose:80.70

bone:-

skin:177.60

GeneChip

cerebrum:5.18

cerebellum:5.13

brain stem:5.30

corpus callosum/glia:5.06

pineal gland:-

peripheral nerve:7.27

spine:6.86

retina:-

eye:-

artery/aorta:7.63

vein:6.86

lymphnode:6.90

peripheral blood:-

spleen:5.28

thymus:7.06

bone marrow:8.69

adipose:7.21

bone:-

skin:8.84

CAGE

cerebrum:0.91

cerebellum:-

brain stem:2.47

corpus callosum/glia:1.72

pineal gland:2.11

peripheral nerve:-

spine:2.84

retina:-

eye:-

artery/aorta:7.79

vein:4.01

lymphnode:5.01

peripheral blood:-

spleen:2.12

thymus:3.60

bone marrow:-

adipose:2.52

bone:-

skin:-

RNA-seq

cerebrum:1.26

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:6.48

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.36

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:51

prostate:112.60

ovary:-

testis:21.60

heart:114.90

muscle:-

esophagus:-

stomach:21.20

intestine:-

colon:25.40

liver/hepato:179.40

lung:68.40

bladder:-

kidney:20.80

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:37.20

salivary:656.80

GeneChip

uterus:7.92

placenta:5.35

prostate:7.28

ovary:8.22

testis:6.68

heart:7.52

muscle:5.57

esophagus:11.89

stomach:7.85

intestine:7.55

colon:7.49

liver/hepato:7.54

lung:10.41

bladder:-

kidney:5.93

pituitary:8.74

thyroid/parathyroid:7.01

adrenal gland:5.67

pancreas:6.79

breast:8.54

salivary:12.56

CAGE

uterus:6.76

placenta:3.25

prostate:5.54

ovary:4.59

testis:4.37

heart:2.55

muscle:6.01

esophagus:6.30

stomach:-

intestine:1.84

colon:3.95

liver/hepato:5.71

lung:7.39

bladder:5.75

kidney:5.69

pituitary:5.87

thyroid/parathyroid:3.56

adrenal gland:-

pancreas:4.57

breast:4.27

salivary:8.77

RNA-seq

uterus:-

placenta:-

prostate:8.44

ovary:5.66

testis:5.39

heart:1.74

muscle:9.64

esophagus:-

stomach:-

intestine:-

colon:5.08

liver/hepato:6.95

lung:9.81

bladder:-

kidney:7.67

pituitary:-

thyroid/parathyroid:4.94

adrenal gland:3.39

pancreas:-

breast:5.25

salivary:-

IDs

Refseq ID	NM_003064
Gene ID	6590
Unigene ID	Hs.517070
Probe set ID	203021_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000124107
GTEx ID	ENSG00000124107

Orthologous Gene

Mouse[1]	NM_011414
Rat[1]	NM_001008873, NM_001008872, NM_053372

Chromosomal Region

20q13.12 [43,880,880 - 43,883,205]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR015874	4-disulphide core
IPR008197	Whey acidic protein, 4-disulphide core

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0010951	negative regulation of endopeptidase activity
GO:0032091	negative regulation of protein binding
GO:0045071	negative regulation of viral genome replication

Cellular Component

GO:0031012	extracellular matrix
GO:0005576	extracellular region

Molecular Function

GO:0004866	endopeptidase inhibitor activity
GO:0019899	enzyme binding
GO:0005515	protein binding
GO:0004867	serine-type endopeptidase inhibitor activity

secretory leukocyte peptidase inhibitor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function