spastin

jump to detail

Synonym

FSP2, ADPSP, Spastin, SPAST, spastin, KIAA1083, SPG4

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:34.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:118.60

eye:41.10

artery/aorta:60

vein:-

lymphnode:40.40

peripheral blood:18.20

spleen:18.90

thymus:12.90

bone marrow:-

adipose:-

bone:-

skin:129.60

GeneChip

cerebrum:3.39

cerebellum:3.41

brain stem:3.48

corpus callosum/glia:3.54

pineal gland:-

peripheral nerve:3.20

spine:3.73

retina:-

eye:-

artery/aorta:2.93

vein:3.02

lymphnode:2.93

peripheral blood:-

spleen:3.10

thymus:4.22

bone marrow:3.56

adipose:2.98

bone:-

skin:2.91

CAGE

cerebrum:2.75

cerebellum:-

brain stem:3.12

corpus callosum/glia:3.12

pineal gland:2.35

peripheral nerve:-

spine:2.72

retina:-

eye:-

artery/aorta:1.33

vein:1.73

lymphnode:1.57

peripheral blood:-

spleen:1.36

thymus:2.64

bone marrow:-

adipose:1.47

bone:-

skin:-

RNA-seq

cerebrum:2.50

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.52

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.03

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:10.90

prostate:11.30

ovary:-

testis:13

heart:-

muscle:80.40

esophagus:-

stomach:-

intestine:-

colon:8.50

liver/hepato:10.60

lung:39.10

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:8.90

breast:18.60

salivary:-

GeneChip

uterus:3.27

placenta:3.35

prostate:3.12

ovary:3.24

testis:3.71

heart:2.99

muscle:3.11

esophagus:2.93

stomach:3.03

intestine:3.04

colon:2.96

liver/hepato:3.01

lung:3.13

bladder:-

kidney:2.95

pituitary:3.08

thyroid/parathyroid:3.01

adrenal gland:2.84

pancreas:3.12

breast:2.95

salivary:2.97

CAGE

uterus:2.15

placenta:1.43

prostate:1.70

ovary:2.32

testis:2.72

heart:1.38

muscle:2.08

esophagus:1.50

stomach:-

intestine:1.41

colon:0.85

liver/hepato:1.21

lung:1.22

bladder:1.47

kidney:1.17

pituitary:2.04

thyroid/parathyroid:1.53

adrenal gland:-

pancreas:1.59

breast:1.16

salivary:1.15

RNA-seq

uterus:-

placenta:-

prostate:0.79

ovary:0.49

testis:0.00

heart:0.76

muscle:1.18

esophagus:-

stomach:-

intestine:-

colon:0.72

liver/hepato:1.45

lung:0.27

bladder:-

kidney:0.30

pituitary:-

thyroid/parathyroid:0.23

adrenal gland:0.09

pancreas:-

breast:1.06

salivary:-

IDs

Refseq ID	NM_199436
Gene ID	6683
Unigene ID	Hs.468091
Probe set ID	207724_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000021574
GTEx ID	ENSG00000021574

Orthologous Gene

Mouse[4]	NM_001162870, NM_016962
Rat[1]	NM_001108702, NM_016962

Chromosomal Region

2p22.3 [32,288,680 - 32,382,706]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR003593

ATPase, AAA+ type, core

Gene Ontology (GO ID)

Biological Process

GO:0007409	axonogenesis
GO:0008219	cell death
GO:0007109	cytokinesis, completion of separation
GO:0006888	ER to Golgi vesicle-mediated transport
GO:0001578	microtubule bundle formation
GO:0051013	microtubule severing
GO:0031117	positive regulation of microtubule depolymerization
GO:0034214	protein hexamerization
GO:0051260	protein homooligomerization

Cellular Component

GO:0005813	centrosome
GO:0005737	cytoplasm
GO:0031410	cytoplasmic vesicle
GO:0005783	endoplasmic reticulum
GO:0005768	endosome
GO:0016021	integral to membrane
GO:0005874	microtubule
GO:0015630	microtubule cytoskeleton
GO:0030496	midbody
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0005819	spindle

Molecular Function

GO:0043014	alpha-tubulin binding
GO:0005524	ATP binding
GO:0048487	beta-tubulin binding
GO:0008017	microtubule binding
GO:0008568	microtubule-severing ATPase activity
GO:0005515	protein binding

spastin

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function