spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)

Synonym

Fodrin alpha chain, Spectrin alpha chain, brain, SPTA2, Alpha-II spectrin, SPTAN1, Spectrin, non-erythroid alpha chain, spectrin, alpha, non-erythrocytic 1 (alpha-fodrin), (ALPHA)II-SPECTRIN

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:285.60

cerebellum:151.10

brain stem:-

corpus callosum/glia:-

pineal gland:445

peripheral nerve:276

spine:1235.30

retina:237.30

eye:311.50

artery/aorta:299.80

vein:199.90

lymphnode:202.20

peripheral blood:182.20

spleen:151.30

thymus:167.50

bone marrow:196.80

adipose:242

bone:191.90

skin:153.60

GeneChip

cerebrum:9.76

cerebellum:9.79

brain stem:10.02

corpus callosum/glia:9.11

pineal gland:-

peripheral nerve:10.72

spine:9.97

retina:-

eye:-

artery/aorta:9.22

vein:8.84

lymphnode:8.37

peripheral blood:-

spleen:8.38

thymus:8.06

bone marrow:6.98

adipose:8.89

bone:-

skin:8.72

CAGE

cerebrum:6.10

cerebellum:-

brain stem:5.94

corpus callosum/glia:5.79

pineal gland:6.05

peripheral nerve:-

spine:5.73

retina:-

eye:-

artery/aorta:5.47

vein:5.17

lymphnode:4.73

peripheral blood:-

spleen:4.85

thymus:5.00

bone marrow:-

adipose:4.93

bone:-

skin:-

RNA-seq

cerebrum:3.06

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.26

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.82

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:72.90

placenta:200.40

prostate:135.20

ovary:409.90

testis:43.30

heart:76.60

muscle:120.50

esophagus:342.80

stomach:233.70

intestine:32.40

colon:339.20

liver/hepato:52.80

lung:171.10

bladder:-

kidney:31.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:35.60

breast:381

salivary:-

GeneChip

uterus:8.81

placenta:8.05

prostate:8.52

ovary:8.96

testis:9

heart:8.60

muscle:6.64

esophagus:8.52

stomach:8.12

intestine:7.58

colon:8.44

liver/hepato:7.78

lung:8.91

bladder:-

kidney:8.50

pituitary:8.69

thyroid/parathyroid:8.60

adrenal gland:8.59

pancreas:6.60

breast:9.02

salivary:7.68

CAGE

uterus:5.31

placenta:4.96

prostate:4.92

ovary:5.09

testis:5.37

heart:5.29

muscle:3.96

esophagus:4.82

stomach:-

intestine:4.67

colon:4.85

liver/hepato:4.37

lung:5.01

bladder:5.19

kidney:4.82

pituitary:4.70

thyroid/parathyroid:4.55

adrenal gland:-

pancreas:4.16

breast:4.80

salivary:4.84

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.00

testis:0.00

heart:0.52

muscle:0.58

esophagus:-

stomach:-

intestine:-

colon:0.66

liver/hepato:0.00

lung:0.51

bladder:-

kidney:0.00

pituitary:-

thyroid/parathyroid:0.01

adrenal gland:0.73

pancreas:-

breast:0.52

salivary:-

IDs

Refseq ID	NM_001130438
Gene ID	6709
Unigene ID	Hs.372331
Probe set ID	208611_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000197694
GTEx ID	ENSG00000197694

Orthologous Gene

Mouse[2]	NM_001076554, NM_001177667, NM_001177668
Rat [0]

Chromosomal Region

9q34.11 [131,314,866 - 131,395,941]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002048	Calcium-binding EF-hand
IPR018249	EF-HAND 2
IPR013315	Spectrin alpha chain, SH3 domain
IPR018159	Spectrin/alpha-actinin
IPR020473	Src homology-3, region

GO:0051693	actin filament capping
GO:0006915	apoptosis
GO:0007411	axon guidance
GO:0006921	cell structure disassembly during apoptosis

GO:0032437	cuticular plate
GO:0005829	cytosol
GO:0005916	fascia adherens
GO:0043231	intracellular membrane-bounded organelle
GO:0016328	lateral plasma membrane
GO:0016020	membrane
GO:0015630	microtubule cytoskeleton
GO:0008091	spectrin
GO:0030018	Z disc

GO:0003779	actin binding
GO:0005509	calcium ion binding
GO:0005516	calmodulin binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0030507	spectrin binding
GO:0005200	structural constituent of cytoskeleton

spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function