tripartite motif-containing 21

Synonym

RNF81, 52 kDa ribonucleoprotein autoantigen Ro/SS-A, 52 kDa Ro protein, RING finger protein 81, TRIM21, SS-A, Sjoegren syndrome type A antigen, Tripartite motif-containing protein 21, RO52, SSA1, Ro(SS-A), SSA, tripartite motif-containing 21

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1.20

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:17.60

artery/aorta:-

vein:-

lymphnode:10.10

peripheral blood:-

spleen:-

thymus:12.90

bone marrow:39.40

adipose:-

bone:38.40

skin:14.40

GeneChip

cerebrum:6.12

cerebellum:6.16

brain stem:6.06

corpus callosum/glia:6.29

pineal gland:-

peripheral nerve:6.80

spine:6.35

retina:-

eye:-

artery/aorta:6.90

vein:6.77

lymphnode:7.15

peripheral blood:-

spleen:7.73

thymus:6.84

bone marrow:7.05

adipose:6.90

bone:-

skin:6.61

CAGE

cerebrum:1.40

cerebellum:-

brain stem:1.68

corpus callosum/glia:1.80

pineal gland:1.29

peripheral nerve:-

spine:1.45

retina:-

eye:-

artery/aorta:2.15

vein:2.31

lymphnode:2.73

peripheral blood:-

spleen:2.68

thymus:2.73

bone marrow:-

adipose:2.80

bone:-

skin:-

RNA-seq

cerebrum:1.22

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.37

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.20

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:32.80

prostate:-

ovary:37.30

testis:-

heart:12.80

muscle:-

esophagus:-

stomach:42.50

intestine:-

colon:25.40

liver/hepato:31.70

lung:39.10

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:44.50

breast:9.30

salivary:-

GeneChip

uterus:6.84

placenta:6.73

prostate:6.69

ovary:6.82

testis:6.05

heart:6.67

muscle:6.29

esophagus:6.75

stomach:7.10

intestine:6.56

colon:6.93

liver/hepato:6.79

lung:7.11

bladder:-

kidney:6.68

pituitary:6.55

thyroid/parathyroid:6.86

adrenal gland:6.64

pancreas:6.68

breast:6.81

salivary:6.61

CAGE

uterus:2.52

placenta:2.79

prostate:2.82

ovary:2.71

testis:1.79

heart:1.97

muscle:0.74

esophagus:2.55

stomach:-

intestine:2.89

colon:2.34

liver/hepato:2.43

lung:2.50

bladder:2.29

kidney:2.41

pituitary:2.13

thyroid/parathyroid:2.74

adrenal gland:-

pancreas:2.18

breast:1.92

salivary:1.82

RNA-seq

uterus:-

placenta:-

prostate:3.22

ovary:3.40

testis:2.31

heart:1.96

muscle:1.38

esophagus:-

stomach:-

intestine:-

colon:2.21

liver/hepato:2.63

lung:3.14

bladder:-

kidney:3.08

pituitary:-

thyroid/parathyroid:2.65

adrenal gland:3.38

pancreas:-

breast:2.79

salivary:-

IDs

Refseq ID	NM_003141
Gene ID	6737
Unigene ID	Hs.532357
Probe set ID	204804_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000132109
GTEx ID	ENSG00000132109

Orthologous Gene

Mouse[4]	NM_001082552, NM_009277
Rat[1]	NM_001082572, NM_009277

Chromosomal Region

11p15.4 [4,406,127 - 4,414,926]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001870	B302 (SPRY)-like
IPR003879	Butyrophylin-like
IPR003877	SPla/RYanodine receptor SPRY
IPR018355	SPla/RYanodine receptor subgroup
IPR003613	U box domain
IPR000315	Zinc finger, B-box
IPR020457	Zinc finger, B-box, chordata
IPR013083	Zinc finger, RING/FYVE/PHD-type

Gene Ontology (GO ID)

Biological Process

GO:0007049	cell cycle
GO:0045087	innate immune response
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0090086	negative regulation of protein deubiquitination
GO:0045787	positive regulation of cell cycle
GO:0032481	positive regulation of type I interferon production
GO:0051865	protein autoubiquitination
GO:0031648	protein destabilization
GO:0006513	protein monoubiquitination
GO:0000209	protein polyubiquitination
GO:0070206	protein trimerization
GO:0016567	protein ubiquitination
GO:0032479	regulation of type I interferon production

Cellular Component

GO:0005737	cytoplasm
GO:0000932	cytoplasmic mRNA processing body
GO:0005829	cytosol
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0030529	ribonucleoprotein complex
GO:0019005	SCF ubiquitin ligase complex

Molecular Function

GO:0003677	DNA binding
GO:0005515	protein binding
GO:0003723	RNA binding
GO:0004842	ubiquitin-protein ligase activity
GO:0008270	zinc ion binding

tripartite motif-containing 21

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function