HNF1 homeobox B

Synonym

TCF-2, HNF1B, Variant hepatic nuclear factor 1, VHNF1, HNF-1B, HNF-1beta, FJHN, MODY5, HNF1beta, LFB3, Transcription factor 2, HNF2, Hepatocyte nuclear factor 1-beta, Homeoprotein LFB3, TCF2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

nodata

CAGE

cerebrum:0.01

cerebellum:-

brain stem:0

corpus callosum/glia:0

pineal gland:0

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:0

vein:0

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.03

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

nodata

CAGE

uterus:1.04

placenta:0.77

prostate:1.53

ovary:1.11

testis:1.35

heart:0

muscle:0

esophagus:0.09

stomach:-

intestine:2.49

colon:2.66

liver/hepato:2.57

lung:2.35

bladder:0.98

kidney:4.83

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:3.47

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.02

ovary:0.22

testis:0.98

heart:0

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.86

liver/hepato:0.56

lung:0.19

bladder:-

kidney:3.23

pituitary:-

thyroid/parathyroid:0.01

adrenal gland:0.03

pancreas:-

breast:0

salivary:-

IDs

Refseq ID	NM_001165923
Gene ID	6928
Unigene ID	-
Probe set ID	-
Ensembl ID	ENSG00000108753
GTEx ID	ENSG00000108753

Orthologous Gene

Mouse[2]	NM_009330
Rat[2]	NM_009330

Chromosomal Region

17q12 [36,046,434 - 36,105,237]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001356	Homeobox
IPR009057	Homeodomain-like
IPR012287	Homeodomain-related

Gene Ontology (GO ID)

Biological Process

GO:0009952	anterior/posterior pattern formation
GO:0048754	branching morphogenesis of a tube
GO:0048557	embryonic digestive tract morphogenesis
GO:0031018	endocrine pancreas development
GO:0001714	endodermal cell fate specification
GO:0050673	epithelial cell proliferation
GO:0048806	genitalia development
GO:0030902	hindbrain development
GO:0001826	inner cell mass cell differentiation
GO:0030073	insulin secretion
GO:0001822	kidney development
GO:0043066	negative regulation of apoptosis
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0048793	pronephros development
GO:0042663	regulation of endodermal cell fate specification
GO:0030111	regulation of Wnt receptor signaling pathway
GO:0009749	response to glucose stimulus
GO:0060677	ureteric bud elongation

Cellular Component

GO:0005730	nucleolus
GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity

HNF1 homeobox B

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function