transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)

Synonym

Transcription factor 3, MGC129647, TCF-3, TCF3, MGC129648, ITF1, Transcription factor ITF-1, Transcription factor E2-alpha, Immunoglobulin enhancer-binding factor E12/E47, Immunoglobulin transcription factor 1, Kappa-E2-binding factor, E2A

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:28.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:76.40

artery/aorta:-

vein:-

lymphnode:586.40

peripheral blood:36.40

spleen:75.60

thymus:51.50

bone marrow:-

adipose:40.30

bone:-

skin:33.60

GeneChip

cerebrum:5.74

cerebellum:5.79

brain stem:5.72

corpus callosum/glia:6.19

pineal gland:-

peripheral nerve:5.86

spine:5.87

retina:-

eye:-

artery/aorta:6.20

vein:5.53

lymphnode:7.35

peripheral blood:-

spleen:7.27

thymus:8

bone marrow:7.54

adipose:6.16

bone:-

skin:6.19

CAGE

cerebrum:2.58

cerebellum:-

brain stem:2.66

corpus callosum/glia:3.06

pineal gland:1.75

peripheral nerve:-

spine:2.90

retina:-

eye:-

artery/aorta:2.96

vein:3.98

lymphnode:3.88

peripheral blood:-

spleen:3.85

thymus:4.50

bone marrow:-

adipose:3.11

bone:-

skin:-

RNA-seq

cerebrum:0.48

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.32

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.65

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:36.50

placenta:58.30

prostate:45.10

ovary:74.50

testis:69.20

heart:89.40

muscle:-

esophagus:-

stomach:42.50

intestine:-

colon:93.30

liver/hepato:21.10

lung:63.50

bladder:-

kidney:93.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:17.80

breast:92.90

salivary:-

GeneChip

uterus:6.73

placenta:5.73

prostate:6.37

ovary:6.55

testis:7.99

heart:5.62

muscle:5.32

esophagus:6.06

stomach:6.52

intestine:6.47

colon:6.73

liver/hepato:5.83

lung:6.25

bladder:-

kidney:6.24

pituitary:6.15

thyroid/parathyroid:7.04

adrenal gland:5.91

pancreas:5.82

breast:6.99

salivary:5.98

CAGE

uterus:3.42

placenta:2.90

prostate:3.47

ovary:3.49

testis:4.14

heart:2.80

muscle:2.02

esophagus:3.38

stomach:-

intestine:3.58

colon:3.60

liver/hepato:2.61

lung:3.11

bladder:3.28

kidney:2.79

pituitary:3.25

thyroid/parathyroid:3.26

adrenal gland:-

pancreas:2.86

breast:3.49

salivary:3.03

RNA-seq

uterus:-

placenta:-

prostate:1.74

ovary:2.91

testis:3.85

heart:0.62

muscle:1.13

esophagus:-

stomach:-

intestine:-

colon:2.12

liver/hepato:0.75

lung:1.63

bladder:-

kidney:1.51

pituitary:-

thyroid/parathyroid:1.88

adrenal gland:2.29

pancreas:-

breast:1.67

salivary:-

IDs

Refseq ID	NM_001136139
Gene ID	6929
Unigene ID	Hs.371282
Probe set ID	209153_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000071564
GTEx ID	ENSG00000071564

Orthologous Gene

Mouse[19]	NM_001164147, NM_001164148, NM_001164149, NM_001164150, NM_001164151, NM_001164152, NM_001164153, NM_011548
Rat[3]	NM_001035237, NM_133524, NM_001164149, NM_001164150, NM_001164151, NM_001164152, NM_001164153, NM_011548

Chromosomal Region

19p13.3 [1,609,293 - 1,652,326]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0030183	B cell differentiation
GO:0002326	B cell lineage commitment
GO:0048468	cell development
GO:0000080	G1 phase of mitotic cell cycle
GO:0043966	histone H3 acetylation
GO:0043967	histone H4 acetylation
GO:0033152	immunoglobulin V(D)J recombination
GO:0042692	muscle cell differentiation
GO:0001779	natural killer cell differentiation
GO:0048541	Peyer's patch development
GO:0030890	positive regulation of B cell proliferation
GO:0045787	positive regulation of cell cycle
GO:0051149	positive regulation of muscle cell differentiation
GO:0045666	positive regulation of neuron differentiation
GO:0051091	positive regulation of transcription factor activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0050821	protein stabilization
GO:0006355	regulation of transcription, DNA-dependent
GO:0042493	response to drug
GO:0032496	response to lipopolysaccharide
GO:0033077	T cell differentiation in the thymus
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005737	cytoplasm
GO:0000788	nuclear nucleosome
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0043234	protein complex
GO:0005667	transcription factor complex

Molecular Function

GO:0043425	bHLH transcription factor binding
GO:0003682	chromatin binding
GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0070888	E-box binding
GO:0031435	mitogen-activated protein kinase kinase kinase binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0043565	sequence-specific DNA binding
GO:0003713	transcription coactivator activity
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding
GO:0070491	transcription repressor binding
GO:0070644	vitamin D response element binding

transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function