tight junction protein 1 (zona occludens 1)

Synonym

Tight junction protein 1, MGC133289, ZO1, TJP1, DKFZp686M05161, Tight junction protein ZO-1, tight junction protein 1 (zona occludens 1), Zonula occludens 1 protein, ZO-1, Zona occludens 1 protein

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:8.95

cerebellum:7.16

brain stem:9.11

corpus callosum/glia:9.79

pineal gland:-

peripheral nerve:9.23

spine:9.55

retina:-

eye:-

artery/aorta:8.47

vein:8.63

lymphnode:7.53

peripheral blood:-

spleen:7.76

thymus:5.81

bone marrow:4.42

adipose:8.50

bone:-

skin:8.16

CAGE

cerebrum:4.29

cerebellum:-

brain stem:4.66

corpus callosum/glia:4.96

pineal gland:4.30

peripheral nerve:-

spine:4.62

retina:-

eye:-

artery/aorta:4.25

vein:3.76

lymphnode:3.64

peripheral blood:-

spleen:3.69

thymus:2.02

bone marrow:-

adipose:4.49

bone:-

skin:-

RNA-seq

cerebrum:3.52

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.07

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.29

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:9.12

placenta:8.48

prostate:8.70

ovary:8.80

testis:8.79

heart:8.82

muscle:7.63

esophagus:8.81

stomach:8.25

intestine:7.98

colon:7.35

liver/hepato:7.65

lung:9.08

bladder:-

kidney:8.04

pituitary:7.66

thyroid/parathyroid:8.55

adrenal gland:8.22

pancreas:7.48

breast:8.27

salivary:7.68

CAGE

uterus:4.66

placenta:4.28

prostate:4.23

ovary:4.51

testis:4.64

heart:4.54

muscle:4.05

esophagus:4.33

stomach:-

intestine:4.03

colon:3.87

liver/hepato:3.64

lung:4.61

bladder:4.29

kidney:4.01

pituitary:4.08

thyroid/parathyroid:4.02

adrenal gland:-

pancreas:3.75

breast:4.32

salivary:3.49

RNA-seq

uterus:-

placenta:-

prostate:3.53

ovary:4.66

testis:4.94

heart:2.45

muscle:1.60

esophagus:-

stomach:-

intestine:-

colon:3.63

liver/hepato:1.76

lung:1.85

bladder:-

kidney:3.60

pituitary:-

thyroid/parathyroid:3.20

adrenal gland:3.80

pancreas:-

breast:3.85

salivary:-

IDs

Refseq ID	NM_175610
Gene ID	7082
Unigene ID	-
Probe set ID	202011_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000104067
GTEx ID	ENSG00000104067

Orthologous Gene

Mouse[2]	NM_001163574, NM_009386
Rat[1]	NM_001106266, NM_009386

Chromosomal Region

15q13.1 [29,991,571 - 30,248,497]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR008144	Guanylate kinase
IPR008145	Guanylate kinase/L-type calcium channel
IPR005417	Zona occludens protein
IPR005418	Zona occludens protein ZO-1

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0001825	blastocyst formation
GO:0006921	cell structure disassembly during apoptosis
GO:0007043	cell-cell junction assembly
GO:0071333	cellular response to glucose stimulus
GO:0016044	membrane organization
GO:0043116	negative regulation of vascular permeability
GO:0042493	response to drug
GO:0045471	response to ethanol
GO:0032496	response to lipopolysaccharide
GO:0071000	response to magnetism

Cellular Component

GO:0043296	apical junction complex
GO:0045177	apical part of cell
GO:0016324	apical plasma membrane
GO:0016327	apicolateral plasma membrane
GO:0016323	basolateral plasma membrane
GO:0030054	cell junction
GO:0005913	cell-cell adherens junction
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005921	gap junction
GO:0014704	intercalated disc
GO:0046581	intercellular canaliculus
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0005923	tight junction

Molecular Function

GO:0005516	calmodulin binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0019904	protein domain specific binding

tight junction protein 1 (zona occludens 1)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function