thioredoxin reductase 1

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Synonym

TXNR, thioredoxin reductase 1, GRIM-12, MGC9145, TRXR1, Thioredoxin reductase 1, cytoplasmic precursor, TXNRD1, Trxr1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:6.95

cerebellum:6.82

brain stem:7.22

corpus callosum/glia:6.61

pineal gland:-

peripheral nerve:7.79

spine:7.13

retina:-

eye:-

artery/aorta:7.94

vein:7.88

lymphnode:7.11

peripheral blood:-

spleen:7.02

thymus:7.81

bone marrow:7.21

adipose:7.23

bone:-

skin:7.01

CAGE

cerebrum:0.71

cerebellum:-

brain stem:0.82

corpus callosum/glia:0.79

pineal gland:0.91

peripheral nerve:-

spine:0.40

retina:-

eye:-

artery/aorta:0.95

vein:0.59

lymphnode:0.31

peripheral blood:-

spleen:0.92

thymus:0.50

bone marrow:-

adipose:0.63

bone:-

skin:-

RNA-seq

cerebrum:0.47

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.40

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.13

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:7.53

placenta:8.21

prostate:7.66

ovary:8.11

testis:7.62

heart:7.86

muscle:8.19

esophagus:6.93

stomach:7.34

intestine:7.49

colon:7.14

liver/hepato:6.99

lung:7.96

bladder:-

kidney:6.98

pituitary:7.61

thyroid/parathyroid:6.85

adrenal gland:8.64

pancreas:6.07

breast:6.94

salivary:6.06

CAGE

uterus:0.89

placenta:0.37

prostate:0.74

ovary:0.92

testis:1.90

heart:0.56

muscle:0.24

esophagus:0.68

stomach:-

intestine:0.48

colon:0.71

liver/hepato:0.96

lung:0.93

bladder:0.83

kidney:0.39

pituitary:0.34

thyroid/parathyroid:0.28

adrenal gland:-

pancreas:1.21

breast:0.55

salivary:0.62

RNA-seq

uterus:-

placenta:-

prostate:1.85

ovary:1.10

testis:1.87

heart:1.07

muscle:1.05

esophagus:-

stomach:-

intestine:-

colon:1.69

liver/hepato:0.25

lung:1.71

bladder:-

kidney:2.35

pituitary:-

thyroid/parathyroid:2.46

adrenal gland:0.31

pancreas:-

breast:0.56

salivary:-

IDs

Refseq ID	NM_003330
Gene ID	7296
Unigene ID	-
Probe set ID	201266_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000198431
GTEx ID	ENSG00000198431

Orthologous Gene

Mouse[24]	NM_001042513, NM_001042514, NM_001042523, NM_015762
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0042537	benzene and derivative metabolic process
GO:0008283	cell proliferation
GO:0045454	cell redox homeostasis
GO:0044255	cellular lipid metabolic process
GO:0071280	cellular response to copper ion
GO:0071455	cellular response to hyperoxia
GO:0022900	electron transport chain
GO:0006749	glutathione metabolic process
GO:0070276	halogen metabolic process
GO:0042744	hydrogen peroxide catabolic process
GO:0001707	mesoderm formation
GO:0042191	methylmercury metabolic process
GO:0070995	NADPH oxidation
GO:0015949	nucleobase, nucleoside and nucleotide interconversion
GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
GO:0001890	placenta development
GO:0010942	positive regulation of cell death
GO:0051262	protein tetramerization
GO:0048678	response to axon injury
GO:0042493	response to drug
GO:0010269	response to selenium ion
GO:0016259	selenocysteine metabolic process
GO:0007165	signal transduction

Cellular Component

GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005739	mitochondrion
GO:0005730	nucleolus
GO:0005634	nucleus

Molecular Function

GO:0009055	electron carrier activity
GO:0050660	FAD binding
GO:0045340	mercury ion binding
GO:0016174	NAD(P)H oxidase activity
GO:0050661	NADP or NADPH binding
GO:0015035	protein disulfide oxidoreductase activity
GO:0042803	protein homodimerization activity
GO:0033797	selenate reductase activity
GO:0004791	thioredoxin-disulfide reductase activity

thioredoxin reductase 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function