ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)

Synonym

UBE2D3, E2(17)KB3, E2(17)KB 3, Ubiquitin-conjugating enzyme E2 D3, MGC43926, UBCH5C, UbcH5C, MGC5416, Ubiquitin carrier protein D3, Ubiquitin-protein ligase D3, Ubiquitin-conjugating enzyme E2-17 kDa 3

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:391.10

cerebellum:617.10

brain stem:-

corpus callosum/glia:583.20

pineal gland:-

peripheral nerve:245.40

spine:112.30

retina:118.60

eye:176.30

artery/aorta:779.40

vein:399.90

lymphnode:273

peripheral blood:491.90

spleen:491.60

thymus:927.60

bone marrow:275.50

adipose:201.70

bone:511.80

skin:249.60

GeneChip

cerebrum:8.26

cerebellum:8.13

brain stem:8.58

corpus callosum/glia:8.62

pineal gland:-

peripheral nerve:8.64

spine:8.80

retina:-

eye:-

artery/aorta:8.69

vein:8.96

lymphnode:9.20

peripheral blood:-

spleen:9.29

thymus:9.95

bone marrow:9.39

adipose:9.27

bone:-

skin:9.33

CAGE

cerebrum:5.38

cerebellum:-

brain stem:5.44

corpus callosum/glia:5.27

pineal gland:5.38

peripheral nerve:-

spine:5.57

retina:-

eye:-

artery/aorta:5.57

vein:5.57

lymphnode:5.70

peripheral blood:-

spleen:5.82

thymus:5.93

bone marrow:-

adipose:5.86

bone:-

skin:-

RNA-seq

cerebrum:1.92

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.34

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:464.80

placenta:273.20

prostate:371.70

ovary:74.50

testis:372.10

heart:319.30

muscle:140.60

esophagus:-

stomach:446.10

intestine:680.40

colon:229

liver/hepato:263.90

lung:493.60

bladder:1130.50

kidney:447.10

pituitary:463.90

thyroid/parathyroid:-

adrenal gland:1269.70

pancreas:213.40

breast:158

salivary:-

GeneChip

uterus:9.10

placenta:9.54

prostate:9.45

ovary:9.37

testis:8.65

heart:9.03

muscle:9.02

esophagus:9.16

stomach:8.93

intestine:9.22

colon:9.12

liver/hepato:8.82

lung:9.46

bladder:-

kidney:9.08

pituitary:8.36

thyroid/parathyroid:9.12

adrenal gland:9.04

pancreas:9.23

breast:9.05

salivary:8.86

CAGE

uterus:5.42

placenta:5.75

prostate:5.61

ovary:5.73

testis:5.54

heart:5.84

muscle:6.02

esophagus:5.75

stomach:-

intestine:5.68

colon:5.45

liver/hepato:5.98

lung:5.83

bladder:5.94

kidney:5.73

pituitary:5.55

thyroid/parathyroid:5.76

adrenal gland:-

pancreas:5.44

breast:5.93

salivary:5.30

RNA-seq

uterus:-

placenta:-

prostate:0.38

ovary:0.97

testis:2.70

heart:1.01

muscle:0.38

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.25

lung:0.57

bladder:-

kidney:0.00

pituitary:-

thyroid/parathyroid:1.24

adrenal gland:0.13

pancreas:-

breast:1.48

salivary:-

IDs

Refseq ID	NM_181890
Gene ID	7323
Unigene ID	Hs.518773
Probe set ID	200668_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000109332
GTEx ID	ENSG00000109332

Orthologous Gene

Mouse[14]	NM_025356
Rat[2]	NM_001037292, NM_031237

Chromosomal Region

4q24 [103,715,540 - 103,790,053]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000608	Ubiquitin-conjugating enzyme, E2
IPR016135	Ubiquitin-conjugating enzyme/RWD-like

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0030509	BMP signaling pathway
GO:0071456	cellular response to hypoxia
GO:0006281	DNA repair
GO:0010467	gene expression
GO:0045087	innate immune response
GO:0002756	MyD88-independent toll-like receptor signaling pathway
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0032480	negative regulation of type I interferon production
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
GO:0070979	protein K11-linked ubiquitination
GO:0070936	protein K48-linked ubiquitination
GO:0006464	protein modification process
GO:0006513	protein monoubiquitination
GO:0000209	protein polyubiquitination
GO:0016567	protein ubiquitination
GO:0034138	toll-like receptor 3 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway
GO:0002224	toll-like receptor signaling pathway
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0006351	transcription, DNA-dependent
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0006511	ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005829	cytosol
GO:0010008	endosome membrane
GO:0005654	nucleoplasm
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0005515	protein binding
GO:0004842	ubiquitin-protein ligase activity

ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function