ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)

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Synonym

Ubiquitin-conjugating enzyme E2 E1, UbcH6, Ubiquitin-protein ligase E1, Ubiquitin carrier protein E1, UBE2E1, UBCH6

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:55.70

cerebellum:-

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:184

spine:-

retina:118.60

eye:82.30

artery/aorta:30

vein:333.20

lymphnode:70.80

peripheral blood:54.70

spleen:18.90

thymus:51.50

bone marrow:59

adipose:-

bone:64

skin:91.20

GeneChip

cerebrum:8.50

cerebellum:8.64

brain stem:8.77

corpus callosum/glia:9.19

pineal gland:-

peripheral nerve:8.73

spine:9.33

retina:-

eye:-

artery/aorta:8.05

vein:8.64

lymphnode:8.94

peripheral blood:-

spleen:9.02

thymus:9.05

bone marrow:8.24

adipose:8.67

bone:-

skin:8.76

CAGE

cerebrum:4.40

cerebellum:-

brain stem:4.51

corpus callosum/glia:4.37

pineal gland:3.80

peripheral nerve:-

spine:4.95

retina:-

eye:-

artery/aorta:4.43

vein:4.40

lymphnode:4.47

peripheral blood:-

spleen:4.43

thymus:4.21

bone marrow:-

adipose:4.33

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:136.70

placenta:83.80

prostate:45.10

ovary:74.50

testis:13

heart:89.40

muscle:100.50

esophagus:342.80

stomach:42.50

intestine:129.60

colon:101.80

liver/hepato:31.70

lung:92.90

bladder:-

kidney:52

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:124.50

breast:46.50

salivary:-

GeneChip

uterus:9.06

placenta:8.79

prostate:9.35

ovary:9.14

testis:8.82

heart:8.49

muscle:8.21

esophagus:9.01

stomach:8.61

intestine:8.83

colon:8.51

liver/hepato:7.81

lung:8.92

bladder:-

kidney:8.55

pituitary:7.82

thyroid/parathyroid:9.04

adrenal gland:8.27

pancreas:8.31

breast:8.98

salivary:8.67

CAGE

uterus:4.59

placenta:4.35

prostate:4.57

ovary:4.25

testis:4.20

heart:4.67

muscle:4.61

esophagus:4.91

stomach:-

intestine:4.10

colon:4.69

liver/hepato:4.03

lung:4.52

bladder:4.83

kidney:4.30

pituitary:4.11

thyroid/parathyroid:4.52

adrenal gland:-

pancreas:4.21

breast:4.83

salivary:4.37

RNA-seq

uterus:-

placenta:-

prostate:0.94

ovary:0.00

testis:0.00

heart:0.00

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.00

lung:1.08

bladder:-

kidney:0.00

pituitary:-

thyroid/parathyroid:0.00

adrenal gland:0.00

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_182666
Gene ID	7324
Unigene ID	Hs.164853
Probe set ID	212519_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000170142
GTEx ID	ENSG00000170142

Orthologous Gene

Mouse[1]	NM_009455
Rat[1]	NM_009455

Chromosomal Region

3p24.3 [23,847,394 - 23,932,807]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000608	Ubiquitin-conjugating enzyme, E2
IPR016135	Ubiquitin-conjugating enzyme/RWD-like

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0019221	cytokine-mediated signaling pathway
GO:0033523	histone H2B ubiquitination
GO:0010390	histone monoubiquitination
GO:0032020	ISG15-protein conjugation
GO:0000278	mitotic cell cycle
GO:0007094	mitotic cell cycle spindle assembly checkpoint
GO:0051436	negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0051437	positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0070936	protein K48-linked ubiquitination
GO:0000209	protein polyubiquitination
GO:0016567	protein ubiquitination
GO:0051439	regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0006511	ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005829	cytosol
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0000151	ubiquitin ligase complex

Molecular Function

GO:0005524	ATP binding
GO:0042296	ISG15 ligase activity
GO:0005515	protein binding
GO:0004842	ubiquitin-protein ligase activity

ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function