ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

Synonym

Ubiquitin thioesterase L1, Neuron cytoplasmic protein 9.5, Ubiquitin carboxyl-terminal hydrolase isozyme L1, PGP 9.5, PARK5, UCH-L1, Uch-L1, PGP9.5, UCHL1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:507.20

cerebellum:125.90

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:214.70

spine:1796.70

retina:237.30

eye:352.60

artery/aorta:60

vein:199.90

lymphnode:30.30

peripheral blood:-

spleen:-

thymus:-

bone marrow:39.40

adipose:-

bone:12.80

skin:153.60

GeneChip

cerebrum:11.05

cerebellum:9.36

brain stem:11.77

corpus callosum/glia:8.91

pineal gland:-

peripheral nerve:12.12

spine:10.40

retina:-

eye:-

artery/aorta:7.65

vein:7.39

lymphnode:5.80

peripheral blood:-

spleen:5.10

thymus:5.89

bone marrow:5.56

adipose:6.92

bone:-

skin:6.28

CAGE

cerebrum:6.21

cerebellum:-

brain stem:6.13

corpus callosum/glia:5.27

pineal gland:4.55

peripheral nerve:-

spine:5.75

retina:-

eye:-

artery/aorta:3.38

vein:3.08

lymphnode:1.86

peripheral blood:-

spleen:1.54

thymus:1.78

bone marrow:-

adipose:3.47

bone:-

skin:-

RNA-seq

cerebrum:8.82

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.92

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.50

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:82

placenta:3.60

prostate:67.60

ovary:260.80

testis:34.60

heart:89.40

muscle:-

esophagus:-

stomach:-

intestine:-

colon:42.40

liver/hepato:-

lung:19.60

bladder:-

kidney:124.80

pituitary:116

thyroid/parathyroid:-

adrenal gland:253.90

pancreas:586.80

breast:9.30

salivary:-

GeneChip

uterus:6.49

placenta:5.50

prostate:7.01

ovary:6.84

testis:7.25

heart:6.11

muscle:7.06

esophagus:6.43

stomach:6.33

intestine:7.10

colon:7.21

liver/hepato:4.77

lung:5.79

bladder:-

kidney:7.88

pituitary:10.36

thyroid/parathyroid:5.85

adrenal gland:6.48

pancreas:7.12

breast:5.93

salivary:4.98

CAGE

uterus:2.78

placenta:2.21

prostate:3.56

ovary:3.77

testis:3.44

heart:2.76

muscle:2.56

esophagus:2.78

stomach:-

intestine:3.18

colon:3.35

liver/hepato:0.63

lung:1.95

bladder:3.81

kidney:4.67

pituitary:5.64

thyroid/parathyroid:1.83

adrenal gland:-

pancreas:2.48

breast:2.59

salivary:1.28

RNA-seq

uterus:-

placenta:-

prostate:5.42

ovary:5.02

testis:4.63

heart:2.49

muscle:2.33

esophagus:-

stomach:-

intestine:-

colon:5.41

liver/hepato:0.47

lung:2.98

bladder:-

kidney:6.03

pituitary:-

thyroid/parathyroid:4.27

adrenal gland:2.69

pancreas:-

breast:6.44

salivary:-

IDs

Refseq ID	NM_004181
Gene ID	7345
Unigene ID	Hs.518731
Probe set ID	201387_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000154277
GTEx ID	ENSG00000154277

Orthologous Gene

Mouse[1]	NM_011670
Rat [0]

Chromosomal Region

4p13 [41,258,430 - 41,270,472]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001578

Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1

Gene Ontology (GO ID)

Biological Process

GO:0007628	adult walking behavior
GO:0007412	axon target recognition
GO:0019896	axon transport of mitochondrion
GO:0008219	cell death
GO:0008283	cell proliferation
GO:0042755	eating behavior
GO:0048747	muscle fiber development
GO:0043407	negative regulation of MAP kinase activity
GO:0050905	neuromuscular process
GO:0016579	protein deubiquitination
GO:0006950	response to stress
GO:0019233	sensory perception of pain
GO:0006511	ubiquitin-dependent protein catabolic process

Cellular Component

GO:0030424	axon
GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005789	endoplasmic reticulum membrane
GO:0005730	nucleolus
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0031694	alpha-2A adrenergic receptor binding
GO:0004197	cysteine-type endopeptidase activity
GO:0016874	ligase activity
GO:0008242	omega peptidase activity
GO:0005515	protein binding
GO:0043130	ubiquitin binding
GO:0004221	ubiquitin thiolesterase activity

ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function