valyl-tRNA synthetase

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Synonym

valyl-tRNA synthetase, ValRS, valyl-tRNA synthetase 2, Valine--tRNA ligase, VARS, G7A, VARS2, Protein G7a, Valyl-tRNA synthetase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:91.30 cerebellum:50.40 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:164.60 artery/aorta:60 vein:- lymphnode:111.20 peripheral blood:145.70 spleen:37.80 thymus:77.30 bone marrow:19.70 adipose:- bone:51.20 skin:48
GeneChip cerebrum:6.47 cerebellum:6.29 brain stem:6.55 corpus callosum/glia:6.33 pineal gland:- peripheral nerve:6.26 spine:6.36 retina:- eye:- artery/aorta:6.27 vein:6.60 lymphnode:6.24 peripheral blood:- spleen:6.21 thymus:6.16 bone marrow:6.65 adipose:6.46 bone:- skin:6.45
CAGE cerebrum:3.40 cerebellum:- brain stem:3.33 corpus callosum/glia:3.19 pineal gland:3.35 peripheral nerve:- spine:3.47 retina:- eye:- artery/aorta:3.30 vein:3.14 lymphnode:3.86 peripheral blood:- spleen:3.75 thymus:3.36 bone marrow:- adipose:3.27 bone:- skin:-
RNA-seq cerebrum:2.73 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.31 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.86 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:47.40 prostate:67.60 ovary:37.30 testis:177.40 heart:12.80 muscle:- esophagus:- stomach:276.10 intestine:- colon:118.70     liver/hepato:63.30        lung:29.30    bladder:- kidney:187.10 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:62.20 breast:74.30 salivary:-
GeneChip uterus:6.27 placenta:6.22 prostate:6.10 ovary:6.28 testis:6.78 heart:6.52 muscle:6.60 esophagus:6.39 stomach:6.36 intestine:6.60 colon:6.53 liver/hepato:6.40 lung:6.29 bladder:- kidney:6.36 pituitary:6.52 thyroid/parathyroid:6.31 adrenal gland:6.49 pancreas:6.99 breast:5.95 salivary:6.43
CAGE uterus:3.05 placenta:3.23 prostate:3.07 ovary:3.41 testis:4.86 heart:3.41 muscle:4.37 esophagus:3.50 stomach:- intestine:3.14 colon:3.41     liver/hepato:4.08    lung:3.46 bladder:3.16 kidney:3.41 pituitary:3.43 thyroid/parathyroid:2.89 adrenal gland:- pancreas:4.03 breast:4.05 salivary:3.22
RNA-seq uterus:- placenta:- prostate:3.11 ovary:3.79 testis:4.71 heart:2.13 muscle:5.29 esophagus:- stomach:- intestine:- colon:2.82     liver/hepato:3.57        lung:2.84    bladder:- kidney:3.31 pituitary:- thyroid/parathyroid:3.81 adrenal gland:4.28 pancreas:- breast:3.20 salivary:-

Gene Information

IDs

Refseq ID NM_006295
Gene ID 7407
Unigene ID Hs.520026
Probe set ID 201796_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000096171
ENSG00000204394
ENSG00000226589
GTEx ID ENSG00000096171
ENSG00000204394
ENSG00000226589

Orthologous Gene

Mouse[1]  NM_011690
Rat[1]  NM_053292

Chromosomal Region

HSCHR6_MHC_APD  [31,756,648  -  31,775,083]
HSCHR6_MHC_QBL  [31,749,636  -  31,753,979]
HSCHR6_MHC_COX  [31,732,662  -  31,751,095]
HSCHR6_MHC_SSTO  [31,735,249  -  31,752,710]
6p21.33  [31,745,295  -  31,763,730]
HSCHR6_MHC_MCF  [31,821,595  -  31,840,030]
HSCHR6_MHC_DBB  [31,727,480  -  31,745,915]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1898367
2477242
2556394
3169261
8294461
8428657
8666263
12477932
14574404
14656967
15161933
15489334
15779907
16229838
17353931
18781797
19380743
19615732
19738201
19851445
19913121
20562859
20628086
21078624
21139048
21145461
21319273
21532573
21890473
21906983
21963094
22053931
22268729
22505724
22623428
22797925
22863883
22939629
23000965
23602568
24457600
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0010467  gene expression
GO:0006414  translational elongation
GO:0006418  tRNA aminoacylation for protein translation
GO:0006438  valyl-tRNA aminoacylation

Cellular Component

GO:0005829  cytosol
GO:0005622  intracellular
GO:0005739  mitochondrion

Molecular Function

GO:0005524  ATP binding
GO:0004832  valine-tRNA ligase activity