tryptophanyl-tRNA synthetase

Synonym

Tryptophanyl-tRNA synthetase, TrpRS, IFI53, tryptophanyl-tRNA synthetase, Tryptophan--tRNA ligase, WARS, IFP53, hWRS, GAMMA-2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:296.30

cerebellum:163.70

brain stem:-

corpus callosum/glia:1866.30

pineal gland:445

peripheral nerve:61.30

spine:112.30

retina:-

eye:152.80

artery/aorta:1438.80

vein:199.90

lymphnode:283.10

peripheral blood:1275.30

spleen:1418

thymus:309.20

bone marrow:78.70

adipose:766.30

bone:1279.50

skin:504

GeneChip

cerebrum:7.09

cerebellum:6.64

brain stem:7.29

corpus callosum/glia:6.44

pineal gland:-

peripheral nerve:7.82

spine:6.97

retina:-

eye:-

artery/aorta:7.92

vein:7.43

lymphnode:7.89

peripheral blood:-

spleen:8.58

thymus:7.35

bone marrow:7.23

adipose:7.78

bone:-

skin:7.36

CAGE

cerebrum:4.25

cerebellum:-

brain stem:4.20

corpus callosum/glia:4.10

pineal gland:4.19

peripheral nerve:-

spine:3.99

retina:-

eye:-

artery/aorta:4.05

vein:4.46

lymphnode:4.46

peripheral blood:-

spleen:5.39

thymus:4.33

bone marrow:-

adipose:5.25

bone:-

skin:-

RNA-seq

cerebrum:3.48

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.74

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:565

placenta:812.40

prostate:180.20

ovary:74.50

testis:272.60

heart:332.10

muscle:100.50

esophagus:342.80

stomach:616

intestine:842.40

colon:135.70

liver/hepato:147.80

lung:782

bladder:1130.50

kidney:249.50

pituitary:116

thyroid/parathyroid:818.70

adrenal gland:152.40

pancreas:106.70

breast:111.50

salivary:-

GeneChip

uterus:7.18

placenta:8.87

prostate:7.49

ovary:7.10

testis:8.33

heart:7.94

muscle:7.68

esophagus:7.15

stomach:7.82

intestine:7.61

colon:7.60

liver/hepato:6.71

lung:9.67

bladder:-

kidney:7.27

pituitary:7.40

thyroid/parathyroid:7.93

adrenal gland:7.52

pancreas:6.82

breast:7.33

salivary:6.88

CAGE

uterus:4.04

placenta:5.77

prostate:4.20

ovary:3.98

testis:4.77

heart:4.94

muscle:4.50

esophagus:4.24

stomach:-

intestine:4.21

colon:3.80

liver/hepato:4.20

lung:5.66

bladder:4.03

kidney:4.62

pituitary:4.23

thyroid/parathyroid:6.45

adrenal gland:-

pancreas:3.98

breast:3.58

salivary:4.43

RNA-seq

uterus:-

placenta:-

prostate:4.36

ovary:3.63

testis:4.52

heart:4.66

muscle:4.66

esophagus:-

stomach:-

intestine:-

colon:1.29

liver/hepato:2.91

lung:6.83

bladder:-

kidney:3.84

pituitary:-

thyroid/parathyroid:4.00

adrenal gland:4.53

pancreas:-

breast:3.80

salivary:-

IDs

Refseq ID	NM_173701
Gene ID	7453
Unigene ID	Hs.497599
Probe set ID	200629_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000140105
GTEx ID	ENSG00000140105

Orthologous Gene

Mouse[10]	NM_001164314, NM_001164488, NM_011710
Rat[1]	NM_001013170, NM_001164488, NM_011710

Chromosomal Region

14q32.2 [100,800,125 - 100,843,142]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR009068	S15/NS1, RNA-binding
IPR000738	WHEP-TRS

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0010467	gene expression
GO:0008285	negative regulation of cell proliferation
GO:0045765	regulation of angiogenesis
GO:0006412	translation
GO:0006418	tRNA aminoacylation for protein translation
GO:0006436	tryptophanyl-tRNA aminoacylation

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol

Molecular Function

GO:0005524	ATP binding
GO:0005515	protein binding
GO:0004830	tryptophan-tRNA ligase activity

tryptophanyl-tRNA synthetase

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function