wingless-type MMTV integration site family, member 1

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Synonym

WNT1, Proto-oncogene protein Wnt-1 precursor, INT1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:3.84

cerebellum:3.74

brain stem:3.90

corpus callosum/glia:3.63

pineal gland:-

peripheral nerve:3.69

spine:3.53

retina:-

eye:-

artery/aorta:3.93

vein:3.97

lymphnode:3.68

peripheral blood:-

spleen:3.44

thymus:3.53

bone marrow:3.82

adipose:3.93

bone:-

skin:4.10

CAGE

cerebrum:0.01

cerebellum:-

brain stem:0.03

corpus callosum/glia:0

pineal gland:0

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:0

vein:0

lymphnode:0.17

peripheral blood:-

spleen:0.09

thymus:0

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0.05

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.30

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:3.63

placenta:3.80

prostate:3.65

ovary:3.62

testis:3.76

heart:3.81

muscle:3.97

esophagus:3.65

stomach:3.55

intestine:3.73

colon:3.66

liver/hepato:3.71

lung:3.81

bladder:-

kidney:3.78

pituitary:3.78

thyroid/parathyroid:3.55

adrenal gland:3.69

pancreas:3.66

breast:3.73

salivary:3.67

CAGE

uterus:0

placenta:1.63

prostate:0

ovary:0

testis:0.04

heart:0

muscle:0

esophagus:0

stomach:-

intestine:0.33

colon:0.12

liver/hepato:0

lung:0

bladder:0.09

kidney:0

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.01

ovary:0.02

testis:0.67

heart:0

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0

liver/hepato:0

lung:0.12

bladder:-

kidney:0

pituitary:-

thyroid/parathyroid:0.00

adrenal gland:0.24

pancreas:-

breast:0.01

salivary:-

IDs

Refseq ID	NM_005430
Gene ID	7471
Unigene ID	Hs.248164
Probe set ID	208570_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000125084
GTEx ID	ENSG00000125084

Orthologous Gene

Mouse[1]	NM_021279
Rat[1]	NM_001105714

Chromosomal Region

12q13.12 [49,372,398 - 49,375,459]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR005816	Secreted growth factor Wnt protein
IPR005817	Wnt superfamily
IPR009139	Wnt-1 protein

Gene Ontology (GO ID)

Biological Process

GO:0060348	bone development
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0045165	cell fate commitment
GO:0007267	cell-cell signaling
GO:0071375	cellular response to peptide hormone stimulus
GO:0021551	central nervous system morphogenesis
GO:0021588	cerebellum formation
GO:0021536	diencephalon development
GO:0042770	DNA damage response, signal transduction
GO:0000578	embryonic axis specification
GO:0021797	forebrain anterior/posterior pattern formation
GO:0071425	hemopoietic stem cell proliferation
GO:0070365	hepatocyte differentiation
GO:0042472	inner ear morphogenesis
GO:0030901	midbrain development
GO:0022004	midbrain-hindbrain boundary maturation during brain development
GO:0007520	myoblast fusion
GO:0030514	negative regulation of BMP signaling pathway
GO:0022408	negative regulation of cell-cell adhesion
GO:0010812	negative regulation of cell-substrate adhesion
GO:0045599	negative regulation of fat cell differentiation
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030182	neuron differentiation
GO:0048664	neuron fate determination
GO:0031100	organ regeneration
GO:0008284	positive regulation of cell proliferation
GO:0048146	positive regulation of fibroblast proliferation
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway
GO:0010592	positive regulation of lamellipodium assembly
GO:0045747	positive regulation of Notch signaling pathway
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0051091	positive regulation of transcription factor activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0009611	response to wounding
GO:0060061	Spemann organizer formation
GO:0021527	spinal cord association neuron differentiation
GO:0033077	T cell differentiation in the thymus
GO:0030579	ubiquitin-dependent SMAD protein catabolic process
GO:0016055	Wnt receptor signaling pathway
GO:0060070	Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0005788	endoplasmic reticulum lumen
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005796	Golgi lumen
GO:0005886	plasma membrane
GO:0005578	proteinaceous extracellular matrix

Molecular Function

GO:0005125	cytokine activity
GO:0044212	DNA regulatory region binding
GO:0005109	frizzled binding
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0048018	receptor agonist activity

wingless-type MMTV integration site family, member 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function